FI60014C - Foerfarande foer framstaellning av terapeutiskt anvaendbara n-substituerade 1,3-dihydro-3-fenylspiro(isobensofuran-1,4'-piperidiner) - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara n-substituerade 1,3-dihydro-3-fenylspiro(isobensofuran-1,4'-piperidiner) Download PDF

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Publication number
FI60014C
FI60014C FI761180A FI761180A FI60014C FI 60014 C FI60014 C FI 60014C FI 761180 A FI761180 A FI 761180A FI 761180 A FI761180 A FI 761180A FI 60014 C FI60014 C FI 60014C
Authority
FI
Finland
Prior art keywords
formula
dihydro
isobenzofuran
optionally
amino
Prior art date
Application number
FI761180A
Other languages
English (en)
Finnish (fi)
Other versions
FI60014B (fi
FI761180A (de
Inventor
Solomon Samuel Klioze
Victor John Bauer
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI761180A publication Critical patent/FI761180A/fi
Priority to FI802236A priority Critical patent/FI62092C/fi
Priority to FI802237A priority patent/FI802237A/fi
Publication of FI60014B publication Critical patent/FI60014B/fi
Application granted granted Critical
Publication of FI60014C publication Critical patent/FI60014C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI761180A 1975-04-30 1976-04-28 Foerfarande foer framstaellning av terapeutiskt anvaendbara n-substituerade 1,3-dihydro-3-fenylspiro(isobensofuran-1,4'-piperidiner) FI60014C (fi)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FI802236A FI62092C (fi) 1975-04-30 1980-07-14 Foerfarande foer framstaellning av terapeutiskt anvaendbara 1'bensoyloxi- och hydroxi-1,3-fenyl(isobenzofuran-1,4'-pipe riin)derivat
FI802237A FI802237A (fi) 1975-04-30 1980-07-14 Foerfarande foer framstaellning av terapeutiskt anvaendbara n-substituerade 1,3-dihydrospiro/isobenzofuran-1,4'-piperidiner

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/573,145 US4024263A (en) 1975-04-30 1975-04-30 1,3-Dihydrospiro[isobenzofuran-1,4'-piperidine]s
US57314575 1975-04-30

Publications (3)

Publication Number Publication Date
FI761180A FI761180A (de) 1976-10-31
FI60014B FI60014B (fi) 1981-07-31
FI60014C true FI60014C (fi) 1981-11-10

Family

ID=24290832

Family Applications (1)

Application Number Title Priority Date Filing Date
FI761180A FI60014C (fi) 1975-04-30 1976-04-28 Foerfarande foer framstaellning av terapeutiskt anvaendbara n-substituerade 1,3-dihydro-3-fenylspiro(isobensofuran-1,4'-piperidiner)

Country Status (27)

Country Link
US (1) US4024263A (de)
JP (1) JPS51133273A (de)
AT (1) AT362371B (de)
AU (1) AU498793B2 (de)
BE (1) BE841354A (de)
CA (1) CA1067081A (de)
CH (2) CH626620A5 (de)
DE (1) DE2618579A1 (de)
DK (1) DK192076A (de)
EG (1) EG12288A (de)
ES (2) ES447327A1 (de)
FI (1) FI60014C (de)
FR (1) FR2309226A1 (de)
GB (1) GB1548311A (de)
GR (1) GR59332B (de)
HU (1) HU174754B (de)
IE (1) IE42994B1 (de)
IL (1) IL49477A (de)
LU (1) LU74859A1 (de)
NL (1) NL7604352A (de)
NO (1) NO145619C (de)
NZ (1) NZ180719A (de)
OA (1) OA05319A (de)
PH (1) PH12917A (de)
PT (1) PT65057B (de)
SE (3) SE7604941L (de)
ZA (1) ZA762578B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268515A (en) * 1980-02-04 1981-05-19 Hoechst-Roussel Pharmaceuticals Inc. Spiro[dihydrobenzofuran-piperidines and-pyrrolidines], pharmaceutical compositions thereof and methods of use thereof
WO2011137024A1 (en) * 2010-04-26 2011-11-03 Merck Sharp & Dohme Corp. Novel spiropiperidine prolylcarboxypeptidase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3200118A (en) * 1961-10-31 1965-08-10 Geschickter Fund Med Res Spirocyclic hydrazine imides
US3686186A (en) * 1970-10-05 1972-08-22 William J Houlihan Substituted isochroman or phthalan piperidenes
US3745165A (en) * 1970-10-05 1973-07-10 Sandoz Ag Substituted isochroman or phthalan piperidenes
US3959475A (en) * 1973-12-12 1976-05-25 American Hoechst Corporation Substituted 1,3-dihydrospiro(isobenzofuran)s

Also Published As

Publication number Publication date
FI60014B (fi) 1981-07-31
GR59332B (en) 1977-12-14
IL49477A0 (en) 1976-06-30
CH626620A5 (de) 1981-11-30
AT362371B (de) 1981-05-11
HU174754B (hu) 1980-03-28
AU1346876A (en) 1977-11-03
FR2309226B1 (de) 1978-08-25
ATA314976A (de) 1980-10-15
IE42994L (en) 1976-10-30
AU498793B2 (en) 1979-03-22
JPS51133273A (en) 1976-11-18
CA1067081A (en) 1979-11-27
BE841354A (fr) 1976-11-03
US4024263A (en) 1977-05-17
OA05319A (fr) 1981-02-28
DE2618579A1 (de) 1976-11-18
DK192076A (da) 1976-10-31
PH12917A (en) 1979-10-10
IE42994B1 (en) 1980-12-03
NZ180719A (en) 1978-04-03
IL49477A (en) 1978-08-31
NO145619B (no) 1982-01-18
ES447327A1 (es) 1977-11-01
SE8006597L (sv) 1980-09-19
LU74859A1 (de) 1977-02-08
CH626622A5 (de) 1981-11-30
NO145619C (no) 1982-04-28
ES459821A1 (es) 1978-04-01
FR2309226A1 (fr) 1976-11-26
SE8006598L (sv) 1980-09-19
GB1548311A (en) 1979-07-11
ZA762578B (en) 1977-04-27
PT65057A (fr) 1976-05-01
NO761487L (de) 1976-11-02
NL7604352A (nl) 1976-11-02
SE7604941L (sv) 1976-10-31
EG12288A (en) 1981-06-30
FI761180A (de) 1976-10-31
PT65057B (fr) 1978-01-03

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MM Patent lapsed

Owner name: HOECHST AG