NO145619C - Analogifremgangsmaate til fremstilling av terapeutisk aktive 1,3-dihydrospiro (isobenzofuran-1,4`-piperidiner) - Google Patents

Analogifremgangsmaate til fremstilling av terapeutisk aktive 1,3-dihydrospiro (isobenzofuran-1,4`-piperidiner)

Info

Publication number
NO145619C
NO145619C NO761487A NO761487A NO145619C NO 145619 C NO145619 C NO 145619C NO 761487 A NO761487 A NO 761487A NO 761487 A NO761487 A NO 761487A NO 145619 C NO145619 C NO 145619C
Authority
NO
Norway
Prior art keywords
dihydrospiro
isobenzofuran
piperidines
preparation
therapeutic active
Prior art date
Application number
NO761487A
Other languages
English (en)
Norwegian (no)
Other versions
NO761487L (de
NO145619B (no
Inventor
Solomon Samuel Klioze
Victor John Bauer
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO761487L publication Critical patent/NO761487L/no
Publication of NO145619B publication Critical patent/NO145619B/no
Publication of NO145619C publication Critical patent/NO145619C/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO761487A 1975-04-30 1976-04-29 Analogifremgangsmaate til fremstilling av terapeutisk aktive 1,3-dihydrospiro (isobenzofuran-1,4`-piperidiner) NO145619C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/573,145 US4024263A (en) 1975-04-30 1975-04-30 1,3-Dihydrospiro[isobenzofuran-1,4'-piperidine]s

Publications (3)

Publication Number Publication Date
NO761487L NO761487L (de) 1976-11-02
NO145619B NO145619B (no) 1982-01-18
NO145619C true NO145619C (no) 1982-04-28

Family

ID=24290832

Family Applications (1)

Application Number Title Priority Date Filing Date
NO761487A NO145619C (no) 1975-04-30 1976-04-29 Analogifremgangsmaate til fremstilling av terapeutisk aktive 1,3-dihydrospiro (isobenzofuran-1,4`-piperidiner)

Country Status (27)

Country Link
US (1) US4024263A (de)
JP (1) JPS51133273A (de)
AT (1) AT362371B (de)
AU (1) AU498793B2 (de)
BE (1) BE841354A (de)
CA (1) CA1067081A (de)
CH (2) CH626620A5 (de)
DE (1) DE2618579A1 (de)
DK (1) DK192076A (de)
EG (1) EG12288A (de)
ES (2) ES447327A1 (de)
FI (1) FI60014C (de)
FR (1) FR2309226A1 (de)
GB (1) GB1548311A (de)
GR (1) GR59332B (de)
HU (1) HU174754B (de)
IE (1) IE42994B1 (de)
IL (1) IL49477A (de)
LU (1) LU74859A1 (de)
NL (1) NL7604352A (de)
NO (1) NO145619C (de)
NZ (1) NZ180719A (de)
OA (1) OA05319A (de)
PH (1) PH12917A (de)
PT (1) PT65057B (de)
SE (3) SE7604941L (de)
ZA (1) ZA762578B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268515A (en) * 1980-02-04 1981-05-19 Hoechst-Roussel Pharmaceuticals Inc. Spiro[dihydrobenzofuran-piperidines and-pyrrolidines], pharmaceutical compositions thereof and methods of use thereof
US8785634B2 (en) * 2010-04-26 2014-07-22 Merck Sharp & Dohme Corp Spiropiperidine prolylcarboxypeptidase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3200118A (en) * 1961-10-31 1965-08-10 Geschickter Fund Med Res Spirocyclic hydrazine imides
US3686186A (en) * 1970-10-05 1972-08-22 William J Houlihan Substituted isochroman or phthalan piperidenes
US3745165A (en) * 1970-10-05 1973-07-10 Sandoz Ag Substituted isochroman or phthalan piperidenes
US3959475A (en) * 1973-12-12 1976-05-25 American Hoechst Corporation Substituted 1,3-dihydrospiro(isobenzofuran)s

Also Published As

Publication number Publication date
ATA314976A (de) 1980-10-15
IE42994B1 (en) 1980-12-03
JPS51133273A (en) 1976-11-18
CH626622A5 (de) 1981-11-30
NZ180719A (en) 1978-04-03
FR2309226B1 (de) 1978-08-25
PT65057A (fr) 1976-05-01
PH12917A (en) 1979-10-10
PT65057B (fr) 1978-01-03
IL49477A0 (en) 1976-06-30
NO761487L (de) 1976-11-02
ZA762578B (en) 1977-04-27
FI60014B (fi) 1981-07-31
AU1346876A (en) 1977-11-03
BE841354A (fr) 1976-11-03
ES447327A1 (es) 1977-11-01
FI761180A (de) 1976-10-31
CH626620A5 (de) 1981-11-30
IE42994L (en) 1976-10-30
SE8006597L (sv) 1980-09-19
IL49477A (en) 1978-08-31
OA05319A (fr) 1981-02-28
US4024263A (en) 1977-05-17
NO145619B (no) 1982-01-18
AU498793B2 (en) 1979-03-22
FR2309226A1 (fr) 1976-11-26
AT362371B (de) 1981-05-11
CA1067081A (en) 1979-11-27
GB1548311A (en) 1979-07-11
DE2618579A1 (de) 1976-11-18
ES459821A1 (es) 1978-04-01
LU74859A1 (de) 1977-02-08
EG12288A (en) 1981-06-30
SE8006598L (sv) 1980-09-19
GR59332B (en) 1977-12-14
SE7604941L (sv) 1976-10-31
HU174754B (hu) 1980-03-28
NL7604352A (nl) 1976-11-02
DK192076A (da) 1976-10-31
FI60014C (fi) 1981-11-10

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