FI59799B - Nytt foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-piperazin-1-yl)-kinazolin foer anvaendning som ett antihypertensivt medel - Google Patents

Nytt foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-piperazin-1-yl)-kinazolin foer anvaendning som ett antihypertensivt medel Download PDF

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Publication number
FI59799B
FI59799B FI3514/74A FI351474A FI59799B FI 59799 B FI59799 B FI 59799B FI 3514/74 A FI3514/74 A FI 3514/74A FI 351474 A FI351474 A FI 351474A FI 59799 B FI59799 B FI 59799B
Authority
FI
Finland
Prior art keywords
amino
furoyl
piperazin
quinazoline
reaction
Prior art date
Application number
FI3514/74A
Other languages
English (en)
Finnish (fi)
Other versions
FI351474A (sv
Inventor
Han-Juergen Ernst Hess
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI351474A publication Critical patent/FI351474A/fi
Application granted granted Critical
Publication of FI59799B publication Critical patent/FI59799B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
FI3514/74A 1973-12-05 1974-12-04 Nytt foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-piperazin-1-yl)-kinazolin foer anvaendning som ett antihypertensivt medel FI59799B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/421,992 US3935213A (en) 1973-12-05 1973-12-05 Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives
US42199273 1973-12-05

Publications (2)

Publication Number Publication Date
FI351474A FI351474A (sv) 1975-06-06
FI59799B true FI59799B (fi) 1981-06-30

Family

ID=23672938

Family Applications (1)

Application Number Title Priority Date Filing Date
FI3514/74A FI59799B (fi) 1973-12-05 1974-12-04 Nytt foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-piperazin-1-yl)-kinazolin foer anvaendning som ett antihypertensivt medel

Country Status (32)

Country Link
US (1) US3935213A (sv)
JP (1) JPS5093987A (sv)
AR (1) AR207766A1 (sv)
AT (1) AT342598B (sv)
BE (1) BE822873A (sv)
CA (1) CA1010866A (sv)
CH (1) CH587843A5 (sv)
CS (1) CS189678B2 (sv)
DD (1) DD114950A5 (sv)
DE (1) DE2457911A1 (sv)
DK (1) DK135376B (sv)
EG (1) EG11404A (sv)
ES (1) ES432483A1 (sv)
FI (1) FI59799B (sv)
FR (1) FR2253750B1 (sv)
GB (1) GB1464583A (sv)
HK (1) HK28379A (sv)
IE (1) IE40204B1 (sv)
IL (1) IL46102A (sv)
IN (1) IN140460B (sv)
KE (1) KE2933A (sv)
LU (1) LU71427A1 (sv)
MY (1) MY7900247A (sv)
NL (1) NL7415793A (sv)
NO (1) NO141898C (sv)
PH (1) PH10594A (sv)
PL (1) PL94120B1 (sv)
RO (1) RO65957A (sv)
SE (1) SE411348B (sv)
SU (1) SU563914A3 (sv)
YU (1) YU36948B (sv)
ZA (1) ZA747593B (sv)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4001237A (en) * 1976-02-18 1977-01-04 Bristol-Myers Company Oxazole, isoxazole, thiazole and isothiazole amides
US4060615A (en) * 1976-02-18 1977-11-29 Mead Johnson & Company 2-Piperazinyl-6,7-dimethoxyquinazolines
US4001238A (en) * 1976-02-18 1977-01-04 Bristol-Myers Company 1,3,4-oxadiazole amides
SE435380B (sv) 1976-06-15 1984-09-24 Pfizer Forfarande for framstellning av kinazolinforeningar
US4062844A (en) * 1976-09-20 1977-12-13 Pfizer Inc. Process for preparing hypotensive 2-(4-aroylpiperazin-1-yl)-amino-6,7-dimethoxyquinazolines
FI58125C (fi) * 1976-12-15 1985-01-02 Orion Yhtymae Oy Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolin med blodtryckssaenkande vekan
FI58124C (fi) * 1976-12-15 1980-12-10 Orion Yhtymae Oy Ny mellanprodukt 3,4-dimetoxi-6-(4-(2-furoyl)-1-piperazinyltiokarbamido)-bensonitril foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolin med blodtryckssaenkande verkan
US4138561A (en) * 1977-09-30 1979-02-06 Bristol-Myers Company Cyanocarboxamidines and quinazoline process
IN151190B (sv) * 1978-05-18 1983-03-05 Pfizer
FI67699C (fi) * 1979-01-31 1985-05-10 Orion Yhtymae Oy Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan
US4426382A (en) 1980-02-13 1984-01-17 Sankyo Company Limited 4-Amino-6,7-dimethoxy-2-piperazinylquinazoline derivatives, their preparation and use
US4351832A (en) * 1980-04-18 1982-09-28 American Home Products Corporation 2-(Piperazinyl)-4-pyrimidinamines
US4333937A (en) * 1980-04-18 1982-06-08 American Home Products Corp. 2-(Piperazinyl)-4-pyrimioinamines
FI70411C (fi) * 1980-12-29 1986-09-19 Pfizer Foerfarande foer framstaellning av nya antihypertensiva 4-amino-6,7-dimetoxi-2-piperazinokinazolin derivat
FI79107C (sv) * 1984-06-25 1989-11-10 Orion Yhtymae Oy Förfarande för framställning av stabil -form av prazosinhydroklorid.
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
EP0794178A4 (en) * 1994-11-25 1998-02-25 Nippon Chemiphar Co CHINAZOLIN DERIVATIVES
US6313294B1 (en) 1998-02-04 2001-11-06 Development Center For Biotechnology Process for preparing amides
US20070086958A1 (en) * 2005-10-14 2007-04-19 Medafor, Incorporated Formation of medically useful gels comprising microporous particles and methods of use
US20070087061A1 (en) * 2005-10-14 2007-04-19 Medafor, Incorporated Method and composition for creating and/or activating a platelet-rich gel by contact with a porous particulate material, for use in wound care, tissue adhesion, or as a matrix for delivery of therapeutic components

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines

Also Published As

Publication number Publication date
FR2253750B1 (sv) 1977-10-28
BE822873A (fr) 1975-06-03
FR2253750A1 (sv) 1975-07-04
EG11404A (en) 1978-03-29
CA1010866A (en) 1977-05-24
NL7415793A (nl) 1975-06-09
DK629874A (sv) 1975-07-21
GB1464583A (en) 1977-02-16
NO141898C (no) 1980-06-04
LU71427A1 (sv) 1975-08-20
NO141898B (no) 1980-02-18
IN140460B (sv) 1976-11-13
FI351474A (sv) 1975-06-06
MY7900247A (en) 1979-12-31
CH587843A5 (sv) 1977-05-13
HK28379A (en) 1979-05-11
ZA747593B (en) 1975-12-31
IL46102A (en) 1977-12-30
JPS5093987A (sv) 1975-07-26
DK135376C (sv) 1977-09-26
DD114950A5 (sv) 1975-09-05
YU317874A (en) 1982-06-18
DE2457911A1 (de) 1975-06-12
ATA970274A (de) 1977-08-15
RO65957A (fr) 1979-07-15
PL94120B1 (sv) 1977-07-30
AT342598B (de) 1978-04-10
DK135376B (da) 1977-04-18
AU7553874A (en) 1976-05-20
SE7413960L (sv) 1975-06-06
NO744382L (sv) 1975-06-30
KE2933A (en) 1979-03-30
SU563914A3 (ru) 1977-06-30
YU36948B (en) 1984-08-31
AR207766A1 (es) 1976-10-29
ES432483A1 (es) 1976-11-16
SE411348B (sv) 1979-12-17
PH10594A (en) 1977-07-15
IL46102A0 (en) 1975-02-10
US3935213A (en) 1976-01-27
IE40204B1 (en) 1979-04-11
IE40204L (en) 1975-06-05
CS189678B2 (en) 1979-04-30

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