FI58919C - Foerfarande foer framstaellning av pyrazolo(5,1-a)isokinoliner och 5,6-dihydropyrazolo(5,1-a)isokinoliner med antireproduktiv aktivitet - Google Patents

Foerfarande foer framstaellning av pyrazolo(5,1-a)isokinoliner och 5,6-dihydropyrazolo(5,1-a)isokinoliner med antireproduktiv aktivitet Download PDF

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Publication number
FI58919C
FI58919C FI753046A FI753046A FI58919C FI 58919 C FI58919 C FI 58919C FI 753046 A FI753046 A FI 753046A FI 753046 A FI753046 A FI 753046A FI 58919 C FI58919 C FI 58919C
Authority
FI
Finland
Prior art keywords
formula
group
isoquinoline
alkoxy
pyrazolo
Prior art date
Application number
FI753046A
Other languages
English (en)
Finnish (fi)
Other versions
FI753046A (ru
FI58919B (fi
Inventor
Amedeo Omodei-Sale
Emilio Toia
Giulio Galliani
Leonard J Lerner
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of FI753046A publication Critical patent/FI753046A/fi
Application granted granted Critical
Publication of FI58919B publication Critical patent/FI58919B/fi
Publication of FI58919C publication Critical patent/FI58919C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Peptides Or Proteins (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
FI753046A 1974-11-23 1975-10-31 Foerfarande foer framstaellning av pyrazolo(5,1-a)isokinoliner och 5,6-dihydropyrazolo(5,1-a)isokinoliner med antireproduktiv aktivitet FI58919C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB5085574 1974-11-23
GB50855/74A GB1484615A (en) 1974-11-23 1974-11-23 Tricyclic n-containing derivatives

Publications (3)

Publication Number Publication Date
FI753046A FI753046A (ru) 1976-05-24
FI58919B FI58919B (fi) 1981-01-30
FI58919C true FI58919C (fi) 1981-05-11

Family

ID=10457662

Family Applications (2)

Application Number Title Priority Date Filing Date
FI753045A FI58918C (fi) 1974-11-23 1975-10-31 Foerfarande foer framstaellning av imidazo(2,1-a)isokinoliner och 5,6-dihydro-imidazo(2,1-a)isokinoliner med antireproduktiv aktivitet
FI753046A FI58919C (fi) 1974-11-23 1975-10-31 Foerfarande foer framstaellning av pyrazolo(5,1-a)isokinoliner och 5,6-dihydropyrazolo(5,1-a)isokinoliner med antireproduktiv aktivitet

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI753045A FI58918C (fi) 1974-11-23 1975-10-31 Foerfarande foer framstaellning av imidazo(2,1-a)isokinoliner och 5,6-dihydro-imidazo(2,1-a)isokinoliner med antireproduktiv aktivitet

Country Status (25)

Country Link
US (1) US4075342A (ru)
JP (1) JPS5516513B2 (ru)
AR (2) AR210476A1 (ru)
AT (2) AT344176B (ru)
BE (1) BE835836A (ru)
CA (2) CA1068273A (ru)
CH (2) CH614444A5 (ru)
DD (2) DD122818A5 (ru)
DE (1) DE2551868C2 (ru)
DK (2) DK522275A (ru)
ES (2) ES442864A1 (ru)
FI (2) FI58918C (ru)
FR (1) FR2291747A1 (ru)
GB (1) GB1484615A (ru)
GR (2) GR58292B (ru)
IE (1) IE43567B1 (ru)
IL (1) IL48389A (ru)
IN (2) IN142014B (ru)
LU (2) LU73850A1 (ru)
NL (1) NL165741C (ru)
NO (2) NO143577C (ru)
SE (2) SE421620B (ru)
SU (3) SU578883A3 (ru)
YU (1) YU37328B (ru)
ZA (1) ZA756792B (ru)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4075343A (en) * 1976-09-13 1978-02-21 Pfizer Inc. Anti-allergenic 5-alkoxyimidazo[1,2-A]quinoline-2-carboxylic acids and derivatives thereof
US4313950A (en) * 1978-10-30 1982-02-02 Gruppo Lepetit S.P.A. Antireproductive tricyclic ortho-fused nitrogen containing compounds
GR70248B (ru) * 1978-10-30 1982-09-01 Lepetit Spa
DE2964567D1 (en) * 1978-12-21 1983-02-24 Lepetit Spa New 3h-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them
US4644002A (en) * 1979-02-09 1987-02-17 Roussel Uclaf Imidazo[2,1-C]quinolines, useful as antiallergic agents
IT1150955B (it) * 1980-06-06 1986-12-17 Lepetit Spa Derivati 3h-naft(1.2-d)-imidazolici il procedimento per la loro preparazione, il loro uso come agenti antiinfiammatori e le composizioni farmaceutiche che li contengono
DE3314843A1 (de) * 1983-04-23 1984-10-25 Beiersdorf Ag, 2000 Hamburg 1-amidino-2,3,3a,8-tetrahydro-1h-pyrazolo (5,1-a)isoindol, verfahren zu dessen herstellung, diese verbindung enthaltende zubereitungen und zwischenprodukte
GB8415540D0 (en) * 1984-06-18 1984-07-25 Fujisawa Pharmaceutical Co Imidazoisoquinoline compounds
EP0607076A1 (fr) * 1993-01-15 1994-07-20 Synthelabo Dérivés de 9h-imidazo 1,2-a benzimidazole-3-acétamide à activité GABA
WO1996025411A1 (en) * 1995-02-15 1996-08-22 Neurogen Corporation Certain bridged 4-phenyl-2-aminomethylimidazoles; new dopamine receptor subtype specific ligands
US5948912A (en) * 1995-02-15 1999-09-07 Neurogen Corporation Certain bridged 4-phenyl-2-aminomethylimidazoles; new dopamine receptor subtype specific ligands
TW416953B (en) 1996-09-25 2001-01-01 Takeda Chemical Industries Ltd Tricyclic compounds for eliciting a prostaglandin I2 receptor agonistic effect, their production and use
KR100749794B1 (ko) * 2001-04-19 2007-08-17 에자이 알앤드디 매니지먼트 가부시키가이샤 2-이미노피롤리딘 유도체
JPWO2002098863A1 (ja) * 2001-06-05 2004-09-16 藤沢薬品工業株式会社 縮合イミダゾール誘導体
CN100439336C (zh) * 2003-02-19 2008-12-03 卫材R&D管理有限公司 制备环状苯甲脒衍生物的方法
WO2006033943A2 (en) * 2004-09-17 2006-03-30 Exelixis, Inc Pyrazole kinase modulators and methods of use
WO2017155942A2 (en) * 2016-03-07 2017-09-14 Northwestern University Substituted heterocycles as c-myc targeting agents
US11142504B2 (en) 2016-03-07 2021-10-12 Northwestern University Substituted heterocycles as c-MYC targeting agents
US11420957B2 (en) 2019-06-17 2022-08-23 Northwestern University Substituted heterocycles as c-MYC targeting agents
CN110294758B (zh) * 2019-07-06 2021-10-22 湘潭大学 2-取代5，6-二氢吡唑并[5，1-α]异喹啉、衍生物及其合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1244501A (en) * 1968-03-09 1971-09-02 Aspro Nicholas Ltd Heterocyclic amines
GB1347493A (en) * 1971-02-11 1974-02-27 Aspro Nicholas Ltd Benzazine derivatives

Also Published As

Publication number Publication date
NO143577B (no) 1980-12-01
FI58918C (fi) 1981-05-11
DE2551868A1 (de) 1976-08-12
AT346332B (de) 1978-11-10
NL7512848A (nl) 1976-05-25
DD122819A5 (ru) 1976-11-05
ATA884575A (de) 1977-11-15
CH614208A5 (ru) 1979-11-15
SU569290A3 (ru) 1977-08-15
NO753853L (ru) 1976-05-25
FI753045A (ru) 1976-05-24
IE43567B1 (en) 1981-04-08
CH614444A5 (ru) 1979-11-30
DK522275A (da) 1976-05-24
US4075342A (en) 1978-02-21
DD122818A5 (ru) 1976-11-05
YU37328B (en) 1984-08-31
GR58293B (en) 1977-09-20
SU582764A3 (ru) 1977-11-30
NL165741C (nl) 1981-05-15
CA1068274A (en) 1979-12-18
IL48389A0 (en) 1975-12-31
NO143578B (no) 1980-12-01
BE835836A (fr) 1976-03-16
AT344176B (de) 1978-07-10
YU292775A (en) 1983-04-27
AU8620475A (en) 1977-05-05
AR209459A1 (es) 1977-04-29
GB1484615A (en) 1977-09-01
IE43567L (en) 1976-05-23
AR210476A1 (es) 1977-08-15
FI753046A (ru) 1976-05-24
LU73849A1 (ru) 1976-06-11
DE2551868C2 (de) 1982-07-15
ATA884675A (de) 1978-03-15
GR58292B (en) 1977-09-20
JPS5175098A (ru) 1976-06-29
DK152756C (da) 1988-09-26
IN142014B (ru) 1977-05-21
FI58919B (fi) 1981-01-30
DK522175A (da) 1976-05-24
DK152756B (da) 1988-05-09
JPS5516513B2 (ru) 1980-05-02
ZA756792B (en) 1976-10-27
SE421619B (sv) 1982-01-18
FR2291747B1 (ru) 1978-11-17
NO753854L (ru) 1976-05-25
FR2291747A1 (fr) 1976-06-18
SE421620B (sv) 1982-01-18
SE7513137L (sv) 1976-05-24
LU73850A1 (ru) 1976-06-11
SU578883A3 (ru) 1977-10-30
ES442864A1 (es) 1977-08-16
IN141710B (ru) 1977-04-09
SE7513138L (sv) 1976-05-24
IL48389A (en) 1979-01-31
ES442863A1 (es) 1977-08-16
NO143577C (no) 1981-03-11
FI58918B (fi) 1981-01-30
NL165741B (nl) 1980-12-15
NO143578C (no) 1981-03-11
CA1068273A (en) 1979-12-18

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Owner name: GRUPPO LEPETIT S.P.A.