FI56378C - Foerfarande foer framstaellning av terapeutiskt aktiva 1-(4-bromfenyl)-1-pyridyl-3-dimetylamino-prop-1-enderivat - Google Patents
Foerfarande foer framstaellning av terapeutiskt aktiva 1-(4-bromfenyl)-1-pyridyl-3-dimetylamino-prop-1-enderivat Download PDFInfo
- Publication number
- FI56378C FI56378C FI858/72A FI85872A FI56378C FI 56378 C FI56378 C FI 56378C FI 858/72 A FI858/72 A FI 858/72A FI 85872 A FI85872 A FI 85872A FI 56378 C FI56378 C FI 56378C
- Authority
- FI
- Finland
- Prior art keywords
- pyridyl
- bromophenyl
- dimethylamino
- tyramine
- compound
- Prior art date
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- 239000002270 dispersing agent Substances 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 125000004005 formimidoyl group Chemical group [H]\N=C(/[H])* 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000005457 ice water Substances 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 230000007574 infarction Effects 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 238000007912 intraperitoneal administration Methods 0.000 description 1
- 239000007928 intraperitoneal injection Substances 0.000 description 1
- 239000012263 liquid product Substances 0.000 description 1
- 150000002641 lithium Chemical group 0.000 description 1
- 229910052744 lithium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 239000000395 magnesium oxide Substances 0.000 description 1
- CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 description 1
- 229940057948 magnesium stearate Drugs 0.000 description 1
- AXZKOIWUVFPNLO-UHFFFAOYSA-N magnesium;oxygen(2-) Chemical compound [O-2].[Mg+2] AXZKOIWUVFPNLO-UHFFFAOYSA-N 0.000 description 1
- 229910000372 mercury(II) sulfate Inorganic materials 0.000 description 1
- 239000012452 mother liquor Substances 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- TVMXDCGIABBOFY-UHFFFAOYSA-N octane Chemical compound CCCCCCCC TVMXDCGIABBOFY-UHFFFAOYSA-N 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 229940100691 oral capsule Drugs 0.000 description 1
- 239000006186 oral dosage form Substances 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- CHKVPAROMQMJNQ-UHFFFAOYSA-M potassium bisulfate Chemical compound [K+].OS([O-])(=O)=O CHKVPAROMQMJNQ-UHFFFAOYSA-M 0.000 description 1
- 239000001120 potassium sulphate Substances 0.000 description 1
- 230000001020 rhythmical effect Effects 0.000 description 1
- 229940081974 saccharin Drugs 0.000 description 1
- 235000019204 saccharin Nutrition 0.000 description 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 235000017550 sodium carbonate Nutrition 0.000 description 1
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 229940114926 stearate Drugs 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- 235000011149 sulphuric acid Nutrition 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 150000003512 tertiary amines Chemical class 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 125000003258 trimethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 description 1
- DZGWFCGJZKJUFP-UHFFFAOYSA-O tyraminium Chemical compound [NH3+]CCC1=CC=C(O)C=C1 DZGWFCGJZKJUFP-UHFFFAOYSA-O 0.000 description 1
- 239000002966 varnish Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI791621A FI60706C (fi) | 1971-04-28 | 1979-05-22 | Foerfarande foer framstaellning av terapeutiskt aktiva 1-fenyl-1-pyridyl-3-dimetylamino-prop-1-en-derivat |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE549671 | 1971-04-28 | ||
| SE05496/71A SE361663B (enrdf_load_stackoverflow) | 1971-04-28 | 1971-04-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI56378B FI56378B (fi) | 1979-09-28 |
| FI56378C true FI56378C (fi) | 1980-01-10 |
Family
ID=20266610
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI858/72A FI56378C (fi) | 1971-04-28 | 1972-03-28 | Foerfarande foer framstaellning av terapeutiskt aktiva 1-(4-bromfenyl)-1-pyridyl-3-dimetylamino-prop-1-enderivat |
Country Status (22)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE409706B (sv) * | 1976-05-21 | 1979-09-03 | Astra Pharma Prod | Forfarande for framstellning av n,n-dimetyl-3-(4-bromfenyl)-3-3(3-pyridyl)-allylamin dihydroklorid monohydrat |
| SE7909514L (sv) * | 1979-11-16 | 1981-05-17 | Astra Laekemedel Ab | Nya halofenyl-pyridyl-allylaminderivat |
| CA1327795C (en) * | 1987-08-14 | 1994-03-15 | Jules Freedman | Antidepressants which are aryloxy inadanamines |
| US5585388A (en) * | 1995-04-07 | 1996-12-17 | Sibia Neurosciences, Inc. | Substituted pyridines useful as modulators of acetylcholine receptors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2712020A (en) * | 1948-07-20 | 1955-06-28 | Burroughs Wellcome Co | Heterocyclic allylamines |
-
1971
- 1971-04-28 SE SE05496/71A patent/SE361663B/xx unknown
-
1972
- 1972-03-06 ZA ZA721503A patent/ZA721503B/xx unknown
- 1972-03-23 BE BE781105A patent/BE781105A/xx not_active IP Right Cessation
- 1972-03-28 FI FI858/72A patent/FI56378C/fi active
- 1972-04-05 NO NO1147/72A patent/NO135590C/no unknown
- 1972-04-10 AU AU40965/72A patent/AU469519B2/en not_active Expired
- 1972-04-12 FR FR7212835A patent/FR2134379B1/fr not_active Expired
- 1972-04-19 ES ES401908A patent/ES401908A1/es not_active Expired
- 1972-04-21 CH CH593872A patent/CH577474A5/xx not_active IP Right Cessation
- 1972-04-24 AT AT357372A patent/AT319242B/de not_active IP Right Cessation
- 1972-04-24 SU SU1777511A patent/SU422146A3/ru active
- 1972-04-26 DE DE2220333A patent/DE2220333C3/de not_active Expired
- 1972-04-26 DK DK205772AA patent/DK138987B/da unknown
- 1972-04-27 CY CY876A patent/CY876A/xx unknown
- 1972-04-27 BR BR2598/72A patent/BR7202598D0/pt unknown
- 1972-04-27 CA CA140,717A patent/CA974999A/en not_active Expired
- 1972-04-27 GB GB1958872A patent/GB1366241A/en not_active Expired
- 1972-04-27 IE IE555/72A patent/IE36330B1/xx unknown
- 1972-04-28 NL NLAANVRAGE7205850,A patent/NL170731C/xx not_active IP Right Cessation
- 1972-04-28 JP JP4602272A patent/JPS5512424B1/ja active Pending
-
1976
- 1976-11-04 HK HK695/76*UA patent/HK69576A/xx unknown
-
1980
- 1980-02-15 IT IT47915/80A patent/IT1188904B/it active
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