FI44906C - Analogiamenetelmä terapeuttisesti aktiivisten 11beta, 21-dihydroksi-3, 20-dionien tai 21-hydroksi-3,11,20-trioni-pregna-1,4-dieeni-(17alfa,16 alfa-d)-2'-metyylioksatsoliinien tai näiden 21-esterien valmistamiseks i - Google Patents

Analogiamenetelmä terapeuttisesti aktiivisten 11beta, 21-dihydroksi-3, 20-dionien tai 21-hydroksi-3,11,20-trioni-pregna-1,4-dieeni-(17alfa,16 alfa-d)-2'-metyylioksatsoliinien tai näiden 21-esterien valmistamiseks i

Info

Publication number
FI44906C
FI44906C FI660986A FI98666A FI44906C FI 44906 C FI44906 C FI 44906C FI 660986 A FI660986 A FI 660986A FI 98666 A FI98666 A FI 98666A FI 44906 C FI44906 C FI 44906C
Authority
FI
Finland
Prior art keywords
methyloxazolines
16alpha
11beta
17alpha
pregna
Prior art date
Application number
FI660986A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI44906B (fr
Inventor
Nathansohn Gian Giancomo
Winters Giorgio
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of FI44906B publication Critical patent/FI44906B/fi
Application granted granted Critical
Publication of FI44906C publication Critical patent/FI44906C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0027—Azides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/0025—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa substituted in position 16
    • C07J7/0035—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa substituted in position 16 by a hydroxy group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0057—Nitrogen and oxygen
    • C07J71/0068—Nitrogen and oxygen at position 16(17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Machines (AREA)
FI660986A 1965-04-22 1966-04-16 Analogiamenetelmä terapeuttisesti aktiivisten 11beta, 21-dihydroksi-3, 20-dionien tai 21-hydroksi-3,11,20-trioni-pregna-1,4-dieeni-(17alfa,16 alfa-d)-2'-metyylioksatsoliinien tai näiden 21-esterien valmistamiseks i FI44906C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB17027/65A GB1077392A (en) 1965-04-22 1965-04-22 New steroids
GB3586565 1965-08-20

Publications (2)

Publication Number Publication Date
FI44906B FI44906B (fr) 1971-11-01
FI44906C true FI44906C (fi) 1972-02-10

Family

ID=26252388

Family Applications (2)

Application Number Title Priority Date Filing Date
FI660986A FI44906C (fi) 1965-04-22 1966-04-16 Analogiamenetelmä terapeuttisesti aktiivisten 11beta, 21-dihydroksi-3, 20-dionien tai 21-hydroksi-3,11,20-trioni-pregna-1,4-dieeni-(17alfa,16 alfa-d)-2'-metyylioksatsoliinien tai näiden 21-esterien valmistamiseks i
FI660985A FI44905C (fi) 1965-04-22 1966-04-16 Menetelmä 20-okso-pregnaani-, 20-okso-4-pregneeni- tai 20-okso-5(6)-pr egneeni-(17alfa, 16alfa-d)-oksatsoliinien valmistamiseksi

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI660985A FI44905C (fi) 1965-04-22 1966-04-16 Menetelmä 20-okso-pregnaani-, 20-okso-4-pregneeni- tai 20-okso-5(6)-pr egneeni-(17alfa, 16alfa-d)-oksatsoliinien valmistamiseksi

Country Status (15)

Country Link
US (2) US3436389A (fr)
AT (2) AT265539B (fr)
BE (2) BE679820A (fr)
BR (2) BR6678805D0 (fr)
CH (2) CH453351A (fr)
DE (3) DE1568950A1 (fr)
DK (2) DK117631B (fr)
ES (1) ES325755A1 (fr)
FI (2) FI44906C (fr)
FR (1) FR5645M (fr)
GB (1) GB1077392A (fr)
IL (2) IL25493A (fr)
NL (3) NL6605174A (fr)
NO (2) NO127346B (fr)
SE (2) SE323674B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1119081A (en) * 1966-01-11 1968-07-10 Lepetit Spa New steroids
IT1141930B (it) * 1980-04-28 1986-10-08 Lepetit Spa Esteri idrosolubili di steroido-ossazoli e loro composizioni farmaceutiche
IT1134455B (it) * 1980-11-26 1986-08-13 Lepetit Spa Procedimento per la preparazione di derivati 16alfa-idrossi-17alfa-aminopregnanici
JP2007504123A (ja) * 2003-08-29 2007-03-01 ランバクシー ラボラトリーズ リミテッド Ｉｖ型ホスホジエステラーゼの阻害剤
US20070259874A1 (en) * 2003-11-26 2007-11-08 Palle Venkata P Phosphodiesterase Inhibitors
US20080009535A1 (en) * 2004-08-30 2008-01-10 Sarala Balachandran Inhibitors of phosphodiesterase type-IV
WO2007031838A1 (fr) 2005-09-16 2007-03-22 Ranbaxy Laboratories Limited Pyrazolo[3,4-b]pyridines substituees en tant qu'inhibiteurs de la phosphodiesterase
WO2007045980A1 (fr) * 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Compositions d'inhibiteurs de la phosphodiesterase de type iv
US20090221664A1 (en) 2005-10-19 2009-09-03 Abhijit Ray Pharmaceutical compositions of muscarinic receptor antagonists
US20110021473A1 (en) * 2006-09-22 2011-01-27 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type-iv
WO2008035316A2 (fr) * 2006-09-22 2008-03-27 Ranbaxy Laboratories Limited Inhibiteurs de phosphodiestérase
CN101177443B (zh) * 2006-11-09 2011-08-03 天津药业研究院有限公司 新的甾体化合物及其应用
US20080207659A1 (en) * 2007-02-15 2008-08-28 Asit Kumar Chakraborti Inhibitors of phosphodiesterase type 4
US20110130403A1 (en) * 2007-03-14 2011-06-02 Ranbaxy Laboratories Limited Pyrazolo [3, 4-b] pyridine derivatives as phosphodiesterase inhibitors
MX2009009793A (es) 2007-03-14 2009-10-16 Ranbaxy Lab Ltd Derivados de pirazolo (3,4-b) piridina como inhibidores de fosfodiesterasa.
EP2111861A1 (fr) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Compositions d'inhibiteurs de type IV de la phosphodiestérase

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2874154A (en) * 1954-10-15 1959-02-17 Syntex Sa Process for the production of 20-keto-21-iodo steroids
US2923721A (en) * 1955-12-13 1960-02-02 Lab Francais Chimiotherapie Method of preparing 3-keto delta1, 4 steroids
DE1223376B (de) * 1963-12-14 1966-08-25 Hoechst Ag Verfahren zur Herstellung von 17alpha-Cyan-16alpha-hydroxy-steroiden der Pregnanreihe
US3349084A (en) * 1965-05-17 1967-10-24 Upjohn Co Steroidal [16, 17-d]-2'-isoxazolines of the pregnane series

Also Published As

Publication number Publication date
NO127346B (fr) 1973-06-12
FI44905B (fr) 1971-11-01
BR6679615D0 (pt) 1973-10-23
DE1793662A1 (de) 1972-08-03
DE1568951A1 (de) 1970-06-18
NO128152B (fr) 1973-10-08
IL25494A (en) 1970-03-22
SE323675B (fr) 1970-05-11
DK117631B (da) 1970-05-19
SE323674B (fr) 1970-05-11
FI44905C (fi) 1972-02-10
AT260440B (de) 1968-03-11
FI44906B (fr) 1971-11-01
DE1793662B2 (de) 1973-04-19
GB1077392A (en) 1967-07-26
US3436389A (en) 1969-04-01
DE1793662C3 (de) 1973-11-08
FR5645M (fr) 1967-12-26
DE1568950A1 (de) 1970-11-26
US3413286A (en) 1968-11-26
BE679820A (fr) 1966-10-03
AT265539B (de) 1968-10-10
BR6678805D0 (pt) 1973-09-18
NL6605375A (fr) 1966-10-24
ES325755A1 (es) 1967-02-16
IL25493A (en) 1969-12-31
DK116870B (da) 1970-02-23
NL128816C (fr)
NL6605174A (fr) 1966-10-24
CH453351A (fr) 1968-06-14
CH471833A (fr) 1969-04-30
BE679821A (fr) 1966-10-03

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