FI4188457T3 - Gastriinia vapauttavan peptidin reseptorin antagonistia käsittävä konjugaatti tai sen suola ja sen käyttötapoja - Google Patents

Gastriinia vapauttavan peptidin reseptorin antagonistia käsittävä konjugaatti tai sen suola ja sen käyttötapoja Download PDF

Info

Publication number
FI4188457T3
FI4188457T3 FIEP21778502.1T FI21778502T FI4188457T3 FI 4188457 T3 FI4188457 T3 FI 4188457T3 FI 21778502 T FI21778502 T FI 21778502T FI 4188457 T3 FI4188457 T3 FI 4188457T3
Authority
FI
Finland
Prior art keywords
conjugate
radionuclide
salt
chelating agent
gastrin
Prior art date
Application number
FIEP21778502.1T
Other languages
English (en)
Finnish (fi)
Inventor
Julien Torgue
Tania Stallons
Amy Wong
Amal Saidi
Original Assignee
Orano Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orano Med filed Critical Orano Med
Application granted granted Critical
Publication of FI4188457T3 publication Critical patent/FI4188457T3/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02Linear peptides containing at least one abnormal peptide link
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FIEP21778502.1T 2020-09-28 2021-09-22 Gastriinia vapauttavan peptidin reseptorin antagonistia käsittävä konjugaatti tai sen suola ja sen käyttötapoja FI4188457T3 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20306109.8A EP3973999A1 (en) 2020-09-28 2020-09-28 Conjugate or its salt comprising a gastrin-releasing peptide receptor antagonist and uses thereof
PCT/EP2021/076107 WO2022063850A1 (en) 2020-09-28 2021-09-22 Conjugate or its salt comprising a gastrin-releasing peptide receptor antagonist and uses thereof

Publications (1)

Publication Number Publication Date
FI4188457T3 true FI4188457T3 (fi) 2024-09-23

Family

ID=74180915

Family Applications (1)

Application Number Title Priority Date Filing Date
FIEP21778502.1T FI4188457T3 (fi) 2020-09-28 2021-09-22 Gastriinia vapauttavan peptidin reseptorin antagonistia käsittävä konjugaatti tai sen suola ja sen käyttötapoja

Country Status (21)

Country Link
US (1) US20230372552A1 (enExample)
EP (2) EP3973999A1 (enExample)
JP (1) JP7824281B2 (enExample)
KR (1) KR20230078690A (enExample)
CN (1) CN116322798A (enExample)
AU (1) AU2021348219A1 (enExample)
BR (1) BR112023003690A2 (enExample)
CA (1) CA3189680A1 (enExample)
DK (1) DK4188457T3 (enExample)
ES (1) ES2989009T3 (enExample)
FI (1) FI4188457T3 (enExample)
HR (1) HRP20241285T1 (enExample)
HU (1) HUE068360T2 (enExample)
IL (1) IL300486A (enExample)
LT (1) LT4188457T (enExample)
PL (1) PL4188457T3 (enExample)
PT (1) PT4188457T (enExample)
RS (1) RS65994B1 (enExample)
SI (1) SI4188457T1 (enExample)
SM (1) SMT202400392T1 (enExample)
WO (1) WO2022063850A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025163083A1 (en) 2024-01-31 2025-08-07 Molecular Partners Ag Recobminant dll3 binding proteins and their use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2100900A1 (en) 2008-03-07 2009-09-16 Universitätsspital Basel Bombesin analog peptide antagonist conjugates
US20150217006A1 (en) * 2014-02-06 2015-08-06 Immunomedics, Inc. Al-f-18-labeled, al-f-19-labeled and ga-68-labeled gastrin-releasing peptide receptor (grpr)-antagonists for imaging of prostate cancer
HRP20231458T1 (hr) * 2017-01-12 2024-05-10 Radiomedix Inc. Liječenje stanica raka koje prekomjerno eksprimiraju receptore za somatostatin primjenom derivata oktreotida keliranih sa radioizotopima

Also Published As

Publication number Publication date
JP7824281B2 (ja) 2026-03-04
AU2021348219A1 (en) 2023-03-09
KR20230078690A (ko) 2023-06-02
SI4188457T1 (sl) 2025-01-31
LT4188457T (lt) 2024-12-27
SMT202400392T1 (it) 2024-11-15
PT4188457T (pt) 2024-09-10
CN116322798A (zh) 2023-06-23
WO2022063850A1 (en) 2022-03-31
DK4188457T3 (da) 2024-08-26
US20230372552A1 (en) 2023-11-23
HRP20241285T1 (hr) 2025-01-03
RS65994B1 (sr) 2024-10-31
PL4188457T3 (pl) 2025-01-07
EP3973999A1 (en) 2022-03-30
BR112023003690A2 (pt) 2023-04-04
ES2989009T3 (es) 2024-11-25
IL300486A (en) 2023-04-01
EP4188457A1 (en) 2023-06-07
HUE068360T2 (hu) 2024-12-28
JP2023542218A (ja) 2023-10-05
CA3189680A1 (en) 2022-03-31
EP4188457B1 (en) 2024-07-03

Similar Documents

Publication Publication Date Title
JP7693751B2 (ja) 陽電子放出断層撮影用の化合物
AU2018382479B2 (en) PSMA ligands for imaging and endoradiotherapy
ES2615805T3 (es) Conjugados de antagonista de péptido análogo de la bombesina
JP6749249B2 (ja) Psmaを標的としたイメージング及び放射線治療のための金属/放射性金属標識psma阻害剤
CA2697949A1 (en) Cancer imaging and treatment
US10786497B2 (en) Discrete PEG constructs
WO2023097038A1 (en) Cleavable radioligands for targeting cell surface receptors and uses thereof
US11639373B2 (en) Therapeutic and diagnostic agents for cancer
US20250288704A1 (en) Cxcr4-ligands for diagnostic and therapeutic use and precursors thereof
JP7027325B2 (ja) 炭酸無水酵素ixを標的とする薬剤および方法
FI4188457T3 (fi) Gastriinia vapauttavan peptidin reseptorin antagonistia käsittävä konjugaatti tai sen suola ja sen käyttötapoja
AU2019338221B2 (en) CXCR4-targeted diagnostic and therapeutic agents with reduced species selectivity
JP2023542218A5 (enExample)
HK1259758A1 (en) Compounds for positron emission tomography
EA044558B1 (ru) Агенты для терапии и диагностики рака
HK1153760A (en) Bombesin analog peptide antagonist conjugates