DK4188457T3 - Konjugat eller salt deraf omfattende en Gastrin-frigivende peptidreceptorantagonist og anvendelser deraf - Google Patents

Konjugat eller salt deraf omfattende en Gastrin-frigivende peptidreceptorantagonist og anvendelser deraf Download PDF

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Publication number
DK4188457T3
DK4188457T3 DK21778502.1T DK21778502T DK4188457T3 DK 4188457 T3 DK4188457 T3 DK 4188457T3 DK 21778502 T DK21778502 T DK 21778502T DK 4188457 T3 DK4188457 T3 DK 4188457T3
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DK
Denmark
Prior art keywords
gastrin
conjugate
salt
receptor antagonist
peptide receptor
Prior art date
Application number
DK21778502.1T
Other languages
Danish (da)
English (en)
Inventor
Julien Torgue
Tania Stallons
Amy Wong
Amal Saidi
Original Assignee
Orano Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orano Med filed Critical Orano Med
Application granted granted Critical
Publication of DK4188457T3 publication Critical patent/DK4188457T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK21778502.1T 2020-09-28 2021-09-22 Konjugat eller salt deraf omfattende en Gastrin-frigivende peptidreceptorantagonist og anvendelser deraf DK4188457T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20306109.8A EP3973999A1 (en) 2020-09-28 2020-09-28 Conjugate or its salt comprising a gastrin-releasing peptide receptor antagonist and uses thereof
PCT/EP2021/076107 WO2022063850A1 (en) 2020-09-28 2021-09-22 Conjugate or its salt comprising a gastrin-releasing peptide receptor antagonist and uses thereof

Publications (1)

Publication Number Publication Date
DK4188457T3 true DK4188457T3 (da) 2024-08-26

Family

ID=74180915

Family Applications (1)

Application Number Title Priority Date Filing Date
DK21778502.1T DK4188457T3 (da) 2020-09-28 2021-09-22 Konjugat eller salt deraf omfattende en Gastrin-frigivende peptidreceptorantagonist og anvendelser deraf

Country Status (21)

Country Link
US (1) US20230372552A1 (enExample)
EP (2) EP3973999A1 (enExample)
JP (1) JP7824281B2 (enExample)
KR (1) KR20230078690A (enExample)
CN (1) CN116322798A (enExample)
AU (1) AU2021348219A1 (enExample)
BR (1) BR112023003690A2 (enExample)
CA (1) CA3189680A1 (enExample)
DK (1) DK4188457T3 (enExample)
ES (1) ES2989009T3 (enExample)
FI (1) FI4188457T3 (enExample)
HR (1) HRP20241285T1 (enExample)
HU (1) HUE068360T2 (enExample)
IL (1) IL300486A (enExample)
LT (1) LT4188457T (enExample)
PL (1) PL4188457T3 (enExample)
PT (1) PT4188457T (enExample)
RS (1) RS65994B1 (enExample)
SI (1) SI4188457T1 (enExample)
SM (1) SMT202400392T1 (enExample)
WO (1) WO2022063850A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025163082A1 (en) 2024-01-31 2025-08-07 Molecular Partners Ag Dll3-specific binding constructs and their use in radiotherapy
WO2026150109A1 (en) 2025-01-10 2026-07-16 Molecular Partners Ag Mesothelin-specific binding constructs and their use in radiotherapy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2100900A1 (en) 2008-03-07 2009-09-16 Universitätsspital Basel Bombesin analog peptide antagonist conjugates
US20150217006A1 (en) * 2014-02-06 2015-08-06 Immunomedics, Inc. Al-f-18-labeled, al-f-19-labeled and ga-68-labeled gastrin-releasing peptide receptor (grpr)-antagonists for imaging of prostate cancer
CA3050094C (en) 2017-01-12 2024-01-02 Radiomedix Inc. Treatment of cancer cells overexpressing somatostatin receptors using ocreotide derivatives chelated to radioisotopes

Also Published As

Publication number Publication date
EP4188457B1 (en) 2024-07-03
CN116322798A (zh) 2023-06-23
EP3973999A1 (en) 2022-03-30
EP4188457A1 (en) 2023-06-07
ES2989009T3 (es) 2024-11-25
JP7824281B2 (ja) 2026-03-04
PL4188457T3 (pl) 2025-01-07
AU2021348219A1 (en) 2023-03-09
WO2022063850A1 (en) 2022-03-31
LT4188457T (lt) 2024-12-27
SI4188457T1 (sl) 2025-01-31
SMT202400392T1 (it) 2024-11-15
HUE068360T2 (hu) 2024-12-28
JP2023542218A (ja) 2023-10-05
RS65994B1 (sr) 2024-10-31
BR112023003690A2 (pt) 2023-04-04
CA3189680A1 (en) 2022-03-31
IL300486A (en) 2023-04-01
HRP20241285T1 (hr) 2025-01-03
US20230372552A1 (en) 2023-11-23
KR20230078690A (ko) 2023-06-02
FI4188457T3 (fi) 2024-09-23
PT4188457T (pt) 2024-09-10

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