SMT202400392T1 - Coniugato o il suo sale comprensivo di un antagonista del recettore del peptide di rilascio della gastrina e relativi usi - Google Patents

Coniugato o il suo sale comprensivo di un antagonista del recettore del peptide di rilascio della gastrina e relativi usi

Info

Publication number
SMT202400392T1
SMT202400392T1 SM20240392T SMT202400392T SMT202400392T1 SM T202400392 T1 SMT202400392 T1 SM T202400392T1 SM 20240392 T SM20240392 T SM 20240392T SM T202400392 T SMT202400392 T SM T202400392T SM T202400392 T1 SMT202400392 T1 SM T202400392T1
Authority
SM
San Marino
Prior art keywords
gastrin
conjugate
salt
receptor antagonist
peptide receptor
Prior art date
Application number
SM20240392T
Other languages
English (en)
Italian (it)
Inventor
Amal Saidi
Julien Torgue
Tania Stallons
Amy Wong
Original Assignee
Orano Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orano Med filed Critical Orano Med
Publication of SMT202400392T1 publication Critical patent/SMT202400392T1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SM20240392T 2020-09-28 2021-09-22 Coniugato o il suo sale comprensivo di un antagonista del recettore del peptide di rilascio della gastrina e relativi usi SMT202400392T1 (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20306109.8A EP3973999A1 (en) 2020-09-28 2020-09-28 Conjugate or its salt comprising a gastrin-releasing peptide receptor antagonist and uses thereof
EP21778502.1A EP4188457B1 (en) 2020-09-28 2021-09-22 Conjugate or its salt comprising a gastrin-releasing peptide receptor antagonist and uses thereof
PCT/EP2021/076107 WO2022063850A1 (en) 2020-09-28 2021-09-22 Conjugate or its salt comprising a gastrin-releasing peptide receptor antagonist and uses thereof

Publications (1)

Publication Number Publication Date
SMT202400392T1 true SMT202400392T1 (it) 2024-11-15

Family

ID=74180915

Family Applications (1)

Application Number Title Priority Date Filing Date
SM20240392T SMT202400392T1 (it) 2020-09-28 2021-09-22 Coniugato o il suo sale comprensivo di un antagonista del recettore del peptide di rilascio della gastrina e relativi usi

Country Status (21)

Country Link
US (1) US20230372552A1 (enExample)
EP (2) EP3973999A1 (enExample)
JP (1) JP7824281B2 (enExample)
KR (1) KR20230078690A (enExample)
CN (1) CN116322798A (enExample)
AU (1) AU2021348219A1 (enExample)
BR (1) BR112023003690A2 (enExample)
CA (1) CA3189680A1 (enExample)
DK (1) DK4188457T3 (enExample)
ES (1) ES2989009T3 (enExample)
FI (1) FI4188457T3 (enExample)
HR (1) HRP20241285T1 (enExample)
HU (1) HUE068360T2 (enExample)
IL (1) IL300486A (enExample)
LT (1) LT4188457T (enExample)
PL (1) PL4188457T3 (enExample)
PT (1) PT4188457T (enExample)
RS (1) RS65994B1 (enExample)
SI (1) SI4188457T1 (enExample)
SM (1) SMT202400392T1 (enExample)
WO (1) WO2022063850A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025163082A1 (en) 2024-01-31 2025-08-07 Molecular Partners Ag Dll3-specific binding constructs and their use in radiotherapy
WO2026150109A1 (en) 2025-01-10 2026-07-16 Molecular Partners Ag Mesothelin-specific binding constructs and their use in radiotherapy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2100900A1 (en) 2008-03-07 2009-09-16 Universitätsspital Basel Bombesin analog peptide antagonist conjugates
US20150217006A1 (en) * 2014-02-06 2015-08-06 Immunomedics, Inc. Al-f-18-labeled, al-f-19-labeled and ga-68-labeled gastrin-releasing peptide receptor (grpr)-antagonists for imaging of prostate cancer
CA3050094C (en) 2017-01-12 2024-01-02 Radiomedix Inc. Treatment of cancer cells overexpressing somatostatin receptors using ocreotide derivatives chelated to radioisotopes

Also Published As

Publication number Publication date
EP4188457B1 (en) 2024-07-03
CN116322798A (zh) 2023-06-23
EP3973999A1 (en) 2022-03-30
EP4188457A1 (en) 2023-06-07
ES2989009T3 (es) 2024-11-25
JP7824281B2 (ja) 2026-03-04
PL4188457T3 (pl) 2025-01-07
AU2021348219A1 (en) 2023-03-09
WO2022063850A1 (en) 2022-03-31
LT4188457T (lt) 2024-12-27
SI4188457T1 (sl) 2025-01-31
HUE068360T2 (hu) 2024-12-28
JP2023542218A (ja) 2023-10-05
RS65994B1 (sr) 2024-10-31
BR112023003690A2 (pt) 2023-04-04
CA3189680A1 (en) 2022-03-31
DK4188457T3 (da) 2024-08-26
IL300486A (en) 2023-04-01
HRP20241285T1 (hr) 2025-01-03
US20230372552A1 (en) 2023-11-23
KR20230078690A (ko) 2023-06-02
FI4188457T3 (fi) 2024-09-23
PT4188457T (pt) 2024-09-10

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