FI3654989T3 - Kladribiinin käyttö neuromuskulaarisen autoimmuunisairauden hoitoon - Google Patents

Kladribiinin käyttö neuromuskulaarisen autoimmuunisairauden hoitoon Download PDF

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Publication number
FI3654989T3
FI3654989T3 FIEP18739593.4T FI18739593T FI3654989T3 FI 3654989 T3 FI3654989 T3 FI 3654989T3 FI 18739593 T FI18739593 T FI 18739593T FI 3654989 T3 FI3654989 T3 FI 3654989T3
Authority
FI
Finland
Prior art keywords
cladribine
composition
use according
unit dosage
treatment
Prior art date
Application number
FIEP18739593.4T
Other languages
English (en)
Finnish (fi)
Inventor
Konrad Rejdak
Original Assignee
Chord Therapeutics Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chord Therapeutics Sa filed Critical Chord Therapeutics Sa
Application granted granted Critical
Publication of FI3654989T3 publication Critical patent/FI3654989T3/fi

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
FIEP18739593.4T 2017-07-21 2018-06-28 Kladribiinin käyttö neuromuskulaarisen autoimmuunisairauden hoitoon FI3654989T3 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1711800.1A GB2564717A (en) 2017-07-21 2017-07-21 Use of cladribine for treating autoimmune neuromuscular disease
PCT/GB2018/051801 WO2019016505A1 (en) 2017-07-21 2018-06-28 USE OF CLADRIBINE FOR THE TREATMENT OF AUTOIMMUNE NEUROMUSCULAR DISEASE

Publications (1)

Publication Number Publication Date
FI3654989T3 true FI3654989T3 (fi) 2024-03-21

Family

ID=59771723

Family Applications (1)

Application Number Title Priority Date Filing Date
FIEP18739593.4T FI3654989T3 (fi) 2017-07-21 2018-06-28 Kladribiinin käyttö neuromuskulaarisen autoimmuunisairauden hoitoon

Country Status (16)

Country Link
US (2) US12171775B2 (enExample)
EP (2) EP4292663A3 (enExample)
JP (1) JP7186214B2 (enExample)
CA (1) CA3095893A1 (enExample)
DK (1) DK3654989T3 (enExample)
ES (1) ES2974423T3 (enExample)
FI (1) FI3654989T3 (enExample)
GB (1) GB2564717A (enExample)
HR (1) HRP20240282T1 (enExample)
HU (1) HUE066238T2 (enExample)
LT (1) LT3654989T (enExample)
PL (1) PL3654989T3 (enExample)
PT (1) PT3654989T (enExample)
RS (1) RS65246B1 (enExample)
SI (1) SI3654989T1 (enExample)
WO (1) WO2019016505A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2601786A (en) 2020-12-10 2022-06-15 Chord Therapeutics S A R L Use of cladribine for treating immune brain disease
WO2025125527A1 (en) 2023-12-14 2025-06-19 Ares Trading S.A. Cladribine regimen for treating myasthenia gravis

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1269659A (en) 1984-08-06 1990-05-29 Brigham Young University Method for the production of 2'-deoxyadenosine compounds
US5310732A (en) 1986-02-03 1994-05-10 The Scripps Research Institute 2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis
US5208327A (en) 1991-12-18 1993-05-04 Ortho Pharmaceutical Corporation Intermediates useful in a synthesis of 2-chloro-2'-deoxyadenosine
EP1200102A1 (en) * 1999-07-22 2002-05-02 Supergen, Inc. Methods for treating autoimmune diseases
EP1556010A4 (en) * 2002-10-31 2007-12-05 Supergen Inc PHARMACEUTICAL FORMULATIONS; WHICH ARE ADDRESSED TO CERTAIN REGIONS OF THE STOMACH-DARM TRAKTS
EP1567945A2 (en) * 2002-11-22 2005-08-31 Transclick, Inc. System and method for speech translation using remote devices
MEP34508A (en) 2003-03-28 2011-02-10 Ares Trading Sa Cladribine formulations for improved oral and transmucosal delivery
EP1827461B1 (en) 2004-12-22 2012-02-29 Merck Serono SA Cladribine regimen for treating multiple sclerosis
EP2026832B1 (en) * 2006-05-24 2012-05-02 Merck Serono SA Combination of interferon-beta and a cladribine regimen for treating multiple sclerosis

Also Published As

Publication number Publication date
HUE066238T2 (hu) 2024-07-28
ES2974423T3 (es) 2024-06-27
US20200163986A1 (en) 2020-05-28
HRP20240282T1 (hr) 2024-05-10
US20250302858A1 (en) 2025-10-02
EP4292663A3 (en) 2024-03-20
GB201711800D0 (en) 2017-09-06
RS65246B1 (sr) 2024-03-29
EP3654989B1 (en) 2024-01-03
GB2564717A (en) 2019-01-23
PT3654989T (pt) 2024-02-28
DK3654989T3 (da) 2024-02-26
LT3654989T (lt) 2024-03-25
EP3654989A1 (en) 2020-05-27
JP2020527156A (ja) 2020-09-03
US12171775B2 (en) 2024-12-24
WO2019016505A1 (en) 2019-01-24
SI3654989T1 (sl) 2024-06-28
PL3654989T3 (pl) 2024-05-20
CA3095893A1 (en) 2019-01-24
JP7186214B2 (ja) 2022-12-08
EP4292663A2 (en) 2023-12-20

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