FI20065431A - Modifioitu beeta-laktamaasi ja menetelmä sen valmistamiseksi - Google Patents

Modifioitu beeta-laktamaasi ja menetelmä sen valmistamiseksi Download PDF

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Publication number
FI20065431A
FI20065431A FI20065431A FI20065431A FI20065431A FI 20065431 A FI20065431 A FI 20065431A FI 20065431 A FI20065431 A FI 20065431A FI 20065431 A FI20065431 A FI 20065431A FI 20065431 A FI20065431 A FI 20065431A
Authority
FI
Finland
Prior art keywords
lactamase
preparation
modified beta
beta
modified
Prior art date
Application number
FI20065431A
Other languages
English (en)
Swedish (sv)
Other versions
FI119190B (fi
FI20065431A0 (fi
Inventor
Susanna Kaeaeriaeinen
Nina Wickstrand
Pertti Koski
Original Assignee
Ipsat Therapies Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsat Therapies Oy filed Critical Ipsat Therapies Oy
Publication of FI20065431A0 publication Critical patent/FI20065431A0/fi
Priority to FI20065431A priority Critical patent/FI119190B/fi
Priority to ES07765926.6T priority patent/ES2452321T3/es
Priority to AU2007262916A priority patent/AU2007262916B2/en
Priority to PCT/FI2007/050372 priority patent/WO2007147945A1/en
Priority to KR1020097001283A priority patent/KR101609243B1/ko
Priority to CA2659691A priority patent/CA2659691C/en
Priority to BRPI0713726-5A priority patent/BRPI0713726B1/pt
Priority to JP2009515904A priority patent/JP5306191B2/ja
Priority to CNA200780023477XA priority patent/CN101484577A/zh
Priority to RU2009101795/10A priority patent/RU2009101795A/ru
Priority to EP07765926.6A priority patent/EP2038411B1/en
Priority to NZ573696A priority patent/NZ573696A/en
Priority to US12/304,874 priority patent/US7989192B2/en
Publication of FI20065431A publication Critical patent/FI20065431A/fi
Application granted granted Critical
Publication of FI119190B publication Critical patent/FI119190B/fi
Priority to ZA200810460A priority patent/ZA200810460B/xx
Priority to NO20090297A priority patent/NO342006B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
FI20065431A 2006-06-21 2006-06-21 Modifioitu beta-laktamaasi ja menetelmä sen valmistamiseksi FI119190B (fi)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FI20065431A FI119190B (fi) 2006-06-21 2006-06-21 Modifioitu beta-laktamaasi ja menetelmä sen valmistamiseksi
CNA200780023477XA CN101484577A (zh) 2006-06-21 2007-06-19 经修饰的β-内酰胺酶及其制备方法
EP07765926.6A EP2038411B1 (en) 2006-06-21 2007-06-19 Modified beta-lactamase and method for its preparation
PCT/FI2007/050372 WO2007147945A1 (en) 2006-06-21 2007-06-19 Modified beta-lactamase and method for its preparation
KR1020097001283A KR101609243B1 (ko) 2006-06-21 2007-06-19 변형 베타-락타마제 및 이의 제조 방법
CA2659691A CA2659691C (en) 2006-06-21 2007-06-19 Modified beta-lactamase and method for its preparation
BRPI0713726-5A BRPI0713726B1 (pt) 2006-06-21 2007-06-19 Proteínas metalo-beta-lactamase modificadas, seu uso, métodos para preparação das referidas proteínas e para a produção de uma preparação homogênea de enzima metalo-beta- lactamase, molécula de nucleotídeo, vetor de expressão e microrganismo transgênico
JP2009515904A JP5306191B2 (ja) 2006-06-21 2007-06-19 β‐ラクタマーゼ修飾体およびその調製方法
ES07765926.6T ES2452321T3 (es) 2006-06-21 2007-06-19 Beta-lactamasa modificada y método para su preparación
RU2009101795/10A RU2009101795A (ru) 2006-06-21 2007-06-19 Модифицированная бета-лактамаза и способ ее получения
AU2007262916A AU2007262916B2 (en) 2006-06-21 2007-06-19 Modified beta-lactamase and method for its preparation
NZ573696A NZ573696A (en) 2006-06-21 2007-06-19 Modified beta-lactamase and method for its preparation
US12/304,874 US7989192B2 (en) 2006-06-21 2007-06-19 Modified beta-lactamase and method for its preparation
ZA200810460A ZA200810460B (en) 2006-06-21 2008-12-10 Modified beta-lactamase and method for its preparation
NO20090297A NO342006B1 (no) 2006-06-21 2009-01-19 Modifisert beta-laktamase og fremgangsmåte for fremstilling derav

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20065431A FI119190B (fi) 2006-06-21 2006-06-21 Modifioitu beta-laktamaasi ja menetelmä sen valmistamiseksi
FI20065431 2006-06-21

Publications (3)

Publication Number Publication Date
FI20065431A0 FI20065431A0 (fi) 2006-06-21
FI20065431A true FI20065431A (fi) 2007-12-22
FI119190B FI119190B (fi) 2008-08-29

Family

ID=36651526

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20065431A FI119190B (fi) 2006-06-21 2006-06-21 Modifioitu beta-laktamaasi ja menetelmä sen valmistamiseksi

Country Status (15)

Country Link
US (1) US7989192B2 (fi)
EP (1) EP2038411B1 (fi)
JP (1) JP5306191B2 (fi)
KR (1) KR101609243B1 (fi)
CN (1) CN101484577A (fi)
AU (1) AU2007262916B2 (fi)
BR (1) BRPI0713726B1 (fi)
CA (1) CA2659691C (fi)
ES (1) ES2452321T3 (fi)
FI (1) FI119190B (fi)
NO (1) NO342006B1 (fi)
NZ (1) NZ573696A (fi)
RU (1) RU2009101795A (fi)
WO (1) WO2007147945A1 (fi)
ZA (1) ZA200810460B (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20105572A0 (fi) * 2010-05-24 2010-05-24 Prevab R Lcc Muokattu beeta-laktamaasi ja siihen liittyvät menetelmät ja käytöt
AU2011268310A1 (en) * 2010-06-16 2013-01-10 Abbvie Inc. Comparison of protein samples
EP2689250A1 (en) 2011-03-23 2014-01-29 AbbVie Inc. Methods and systems for the analysis of protein samples
CA2833454C (en) * 2011-04-21 2020-03-10 Biomerieux Inc. Method of detecting at least one mechanism of resistance to cephalosporins by mass spectrometry
KR102360582B1 (ko) 2014-04-17 2022-02-08 신세틱 바이오로직스, 인코퍼레이티드 치료법을 위한 개선된 특성을 지니는 베타-락타마제
AU2015308897B2 (en) 2014-08-28 2021-03-04 Theriva Biologics, Inc. E. coli-based production of beta-lactamase
MX2017004473A (es) 2014-10-08 2017-10-12 Synthetic Biologics Inc Formulaciones de betalactamasa y usos de las mismas.
FR3027307B1 (fr) 2014-10-16 2016-11-04 Azurrx Sas Molecule proteique hybride apte a inhiber au moins un antibiotique et composition pharmaceutique la comportant
WO2016105498A1 (en) 2014-12-23 2016-06-30 Synthetic Biologics, Inc. Methods and compositions for inhibiting or preventing adverse effects of oral antibiotics
AU2016222936B2 (en) 2015-02-23 2022-01-06 Theriva Biologics, Inc. Carbapenemases for use with antibiotics for the protection of the intestinal microbiome
KR20170122776A (ko) 2015-03-06 2017-11-06 신세틱 바이오로직스, 인코퍼레이티드 마이크로바이옴 보호를 위한 안전하고 유효한 베타-락타마제 투약
US10982205B2 (en) 2016-02-23 2021-04-20 Da Volterra Beta-lactamase variants
WO2017144495A1 (en) 2016-02-23 2017-08-31 Da Volterra Beta-lactamase variants
MX2021001393A (es) 2018-08-05 2021-04-12 Da Volterra Composiciones para el tratamiento de la enfermedad de injerto contra huesped.
EP3829637A1 (en) 2018-08-05 2021-06-09 Da Volterra Method for improving anticancer agent efficacy
US20220154156A1 (en) * 2019-03-11 2022-05-19 Regents Of The University Of Minnesota Proteins and methods for disrupting bacterial communication
WO2021137645A1 (ko) * 2019-12-30 2021-07-08 (재)씨젠의료재단 카바페넴 항생제에 대한 내성을 가지는 병원성 균주의 직접 검출 방법
EP4148136A1 (en) 2021-09-08 2023-03-15 Da Volterra An engineered yeast cell for the delivery of antibiotic-inactivating enzymes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI920206A0 (fi) 1992-01-17 1992-01-17 Pekka Untamo Heino Medicinsk anvaendning, medicinskt foerfarande och preparat.
FI112666B (fi) 2001-11-06 2003-12-31 Ipsat Therapies Oy Itiöimätön Bacillus subtilis, sen valmistus ja käyttö
FR2843302B1 (fr) * 2002-08-09 2004-10-22 Centre Nat Rech Scient Forme galenique pour la delivrance colique de principes actifs

Also Published As

Publication number Publication date
AU2007262916A1 (en) 2007-12-27
KR101609243B1 (ko) 2016-04-05
EP2038411A4 (en) 2010-04-07
JP2009540814A (ja) 2009-11-26
BRPI0713726B1 (pt) 2023-01-10
US20090181004A1 (en) 2009-07-16
BRPI0713726A2 (pt) 2012-10-30
JP5306191B2 (ja) 2013-10-02
US7989192B2 (en) 2011-08-02
NO20090297L (no) 2009-01-19
AU2007262916B2 (en) 2013-12-05
ZA200810460B (en) 2009-12-30
CN101484577A (zh) 2009-07-15
EP2038411A1 (en) 2009-03-25
CA2659691A1 (en) 2007-12-27
FI119190B (fi) 2008-08-29
EP2038411B1 (en) 2014-02-26
FI20065431A0 (fi) 2006-06-21
CA2659691C (en) 2015-05-19
RU2009101795A (ru) 2010-07-27
NZ573696A (en) 2011-09-30
NO342006B1 (no) 2018-03-12
WO2007147945A1 (en) 2007-12-27
KR20090046787A (ko) 2009-05-11
WO2007147945A8 (en) 2009-07-30
ES2452321T3 (es) 2014-03-31

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