FI20065431A - Modifioitu beeta-laktamaasi ja menetelmä sen valmistamiseksi - Google Patents

Modifioitu beeta-laktamaasi ja menetelmä sen valmistamiseksi Download PDF

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Publication number
FI20065431A
FI20065431A FI20065431A FI20065431A FI20065431A FI 20065431 A FI20065431 A FI 20065431A FI 20065431 A FI20065431 A FI 20065431A FI 20065431 A FI20065431 A FI 20065431A FI 20065431 A FI20065431 A FI 20065431A
Authority
FI
Finland
Prior art keywords
lactamase
preparation
modified beta
beta
modified
Prior art date
Application number
FI20065431A
Other languages
English (en)
Swedish (sv)
Other versions
FI119190B (fi
FI20065431A0 (fi
Inventor
Susanna Kaeaeriaeinen
Nina Wickstrand
Pertti Koski
Original Assignee
Ipsat Therapies Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsat Therapies Oy filed Critical Ipsat Therapies Oy
Publication of FI20065431A0 publication Critical patent/FI20065431A0/fi
Priority to FI20065431A priority Critical patent/FI119190B/fi
Priority to CA2659691A priority patent/CA2659691C/en
Priority to EP07765926.6A priority patent/EP2038411B1/en
Priority to NZ573696A priority patent/NZ573696A/en
Priority to RU2009101795/10A priority patent/RU2009101795A/ru
Priority to CNA200780023477XA priority patent/CN101484577A/zh
Priority to US12/304,874 priority patent/US7989192B2/en
Priority to BRPI0713726-5A priority patent/BRPI0713726B1/pt
Priority to KR1020097001283A priority patent/KR101609243B1/ko
Priority to PCT/FI2007/050372 priority patent/WO2007147945A1/en
Priority to JP2009515904A priority patent/JP5306191B2/ja
Priority to ES07765926.6T priority patent/ES2452321T3/es
Priority to AU2007262916A priority patent/AU2007262916B2/en
Publication of FI20065431A publication Critical patent/FI20065431A/fi
Application granted granted Critical
Publication of FI119190B publication Critical patent/FI119190B/fi
Priority to ZA200810460A priority patent/ZA200810460B/xx
Priority to NO20090297A priority patent/NO342006B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FI20065431A 2006-06-21 2006-06-21 Modifioitu beta-laktamaasi ja menetelmä sen valmistamiseksi FI119190B (fi)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FI20065431A FI119190B (fi) 2006-06-21 2006-06-21 Modifioitu beta-laktamaasi ja menetelmä sen valmistamiseksi
KR1020097001283A KR101609243B1 (ko) 2006-06-21 2007-06-19 변형 베타-락타마제 및 이의 제조 방법
JP2009515904A JP5306191B2 (ja) 2006-06-21 2007-06-19 β‐ラクタマーゼ修飾体およびその調製方法
NZ573696A NZ573696A (en) 2006-06-21 2007-06-19 Modified beta-lactamase and method for its preparation
RU2009101795/10A RU2009101795A (ru) 2006-06-21 2007-06-19 Модифицированная бета-лактамаза и способ ее получения
CNA200780023477XA CN101484577A (zh) 2006-06-21 2007-06-19 经修饰的β-内酰胺酶及其制备方法
US12/304,874 US7989192B2 (en) 2006-06-21 2007-06-19 Modified beta-lactamase and method for its preparation
BRPI0713726-5A BRPI0713726B1 (pt) 2006-06-21 2007-06-19 Proteínas metalo-beta-lactamase modificadas, seu uso, métodos para preparação das referidas proteínas e para a produção de uma preparação homogênea de enzima metalo-beta- lactamase, molécula de nucleotídeo, vetor de expressão e microrganismo transgênico
CA2659691A CA2659691C (en) 2006-06-21 2007-06-19 Modified beta-lactamase and method for its preparation
PCT/FI2007/050372 WO2007147945A1 (en) 2006-06-21 2007-06-19 Modified beta-lactamase and method for its preparation
EP07765926.6A EP2038411B1 (en) 2006-06-21 2007-06-19 Modified beta-lactamase and method for its preparation
ES07765926.6T ES2452321T3 (es) 2006-06-21 2007-06-19 Beta-lactamasa modificada y método para su preparación
AU2007262916A AU2007262916B2 (en) 2006-06-21 2007-06-19 Modified beta-lactamase and method for its preparation
ZA200810460A ZA200810460B (en) 2006-06-21 2008-12-10 Modified beta-lactamase and method for its preparation
NO20090297A NO342006B1 (no) 2006-06-21 2009-01-19 Modifisert beta-laktamase og fremgangsmåte for fremstilling derav

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20065431 2006-06-21
FI20065431A FI119190B (fi) 2006-06-21 2006-06-21 Modifioitu beta-laktamaasi ja menetelmä sen valmistamiseksi

Publications (3)

Publication Number Publication Date
FI20065431A0 FI20065431A0 (fi) 2006-06-21
FI20065431A true FI20065431A (fi) 2007-12-22
FI119190B FI119190B (fi) 2008-08-29

Family

ID=36651526

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20065431A FI119190B (fi) 2006-06-21 2006-06-21 Modifioitu beta-laktamaasi ja menetelmä sen valmistamiseksi

Country Status (15)

Country Link
US (1) US7989192B2 (fi)
EP (1) EP2038411B1 (fi)
JP (1) JP5306191B2 (fi)
KR (1) KR101609243B1 (fi)
CN (1) CN101484577A (fi)
AU (1) AU2007262916B2 (fi)
BR (1) BRPI0713726B1 (fi)
CA (1) CA2659691C (fi)
ES (1) ES2452321T3 (fi)
FI (1) FI119190B (fi)
NO (1) NO342006B1 (fi)
NZ (1) NZ573696A (fi)
RU (1) RU2009101795A (fi)
WO (1) WO2007147945A1 (fi)
ZA (1) ZA200810460B (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20105572A0 (fi) 2010-05-24 2010-05-24 Prevab R Lcc Muokattu beeta-laktamaasi ja siihen liittyvät menetelmät ja käytöt
EP2582380A4 (en) * 2010-06-16 2014-03-05 Abbvie Inc COMPARISON OF PROTEIN SAMPLES
EP2689250A1 (en) 2011-03-23 2014-01-29 AbbVie Inc. Methods and systems for the analysis of protein samples
WO2012143534A2 (fr) * 2011-04-21 2012-10-26 Biomerieux Inc. Procede de detection d'au moins un mecanisme de resistance aux cephalosporines par spectrometrie de masse
JP6685925B2 (ja) * 2014-04-17 2020-04-22 シンセティック バイオロジクス，インコーポレイテッド 治療用として改善された特性を有するβ−ラクタマーゼ
AU2015308897B2 (en) * 2014-08-28 2021-03-04 Theriva Biologics, Inc. E. coli-based production of beta-lactamase
CA2962959C (en) 2014-10-08 2023-04-04 Synthetic Biologics, Inc. Beta-lactamase formulations and uses thereof
FR3027307B1 (fr) 2014-10-16 2016-11-04 Azurrx Sas Molecule proteique hybride apte a inhiber au moins un antibiotique et composition pharmaceutique la comportant
EP3236993B1 (en) 2014-12-23 2023-09-13 Theriva Biologics, Inc. Methods and compositions for inhibiting or preventing adverse effects of oral antibiotics
US20160250304A1 (en) * 2015-02-23 2016-09-01 Synthetic Biologics, Inc. Carbapenemases for use with antibiotics for the protection of the intestinal microbiome
US10709773B2 (en) 2015-03-06 2020-07-14 Synthetic Biologics, Inc. Safe and effective beta-lactamase dosing for microbiome protection
US10988749B2 (en) 2016-02-23 2021-04-27 Da Volterra Beta-lactamase variants
CA3013166A1 (en) 2016-02-23 2017-08-31 Da Volterra Beta-lactamase variants
CA3106433A1 (en) 2018-08-05 2020-02-13 Da Volterra Compositions for the treatment of graft versus host disease
BR112021002106A2 (pt) 2018-08-05 2021-06-01 Da Volterra método para aprimorar a eficácia de agente anticâncer
US20220154156A1 (en) * 2019-03-11 2022-05-19 Regents Of The University Of Minnesota Proteins and methods for disrupting bacterial communication
WO2021137645A1 (ko) * 2019-12-30 2021-07-08 (재)씨젠의료재단 카바페넴 항생제에 대한 내성을 가지는 병원성 균주의 직접 검출 방법
EP4148136A1 (en) 2021-09-08 2023-03-15 Da Volterra An engineered yeast cell for the delivery of antibiotic-inactivating enzymes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI920206A0 (fi) 1992-01-17 1992-01-17 Pekka Untamo Heino Medicinsk anvaendning, medicinskt foerfarande och preparat.
FI112666B (fi) 2001-11-06 2003-12-31 Ipsat Therapies Oy Itiöimätön Bacillus subtilis, sen valmistus ja käyttö
FR2843302B1 (fr) 2002-08-09 2004-10-22 Centre Nat Rech Scient Forme galenique pour la delivrance colique de principes actifs

Also Published As

Publication number Publication date
AU2007262916B2 (en) 2013-12-05
CN101484577A (zh) 2009-07-15
US20090181004A1 (en) 2009-07-16
ZA200810460B (en) 2009-12-30
WO2007147945A8 (en) 2009-07-30
US7989192B2 (en) 2011-08-02
KR20090046787A (ko) 2009-05-11
BRPI0713726B1 (pt) 2023-01-10
EP2038411B1 (en) 2014-02-26
ES2452321T3 (es) 2014-03-31
FI119190B (fi) 2008-08-29
EP2038411A1 (en) 2009-03-25
RU2009101795A (ru) 2010-07-27
CA2659691A1 (en) 2007-12-27
NZ573696A (en) 2011-09-30
WO2007147945A1 (en) 2007-12-27
JP2009540814A (ja) 2009-11-26
JP5306191B2 (ja) 2013-10-02
AU2007262916A1 (en) 2007-12-27
CA2659691C (en) 2015-05-19
KR101609243B1 (ko) 2016-04-05
FI20065431A0 (fi) 2006-06-21
NO20090297L (no) 2009-01-19
NO342006B1 (no) 2018-03-12
BRPI0713726A2 (pt) 2012-10-30
EP2038411A4 (en) 2010-04-07

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