FI121507B - DNA-kodande människopapillomavirus typ 6A - Google Patents
DNA-kodande människopapillomavirus typ 6A Download PDFInfo
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- FI121507B FI121507B FI971203A FI971203A FI121507B FI 121507 B FI121507 B FI 121507B FI 971203 A FI971203 A FI 971203A FI 971203 A FI971203 A FI 971203A FI 121507 B FI121507 B FI 121507B
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Claims (7)
1. Isolerat DNA, som kodar ett HPV6a-protein, var-vid HPV6a-proteinet väljs frän en grupp, som bestär av föl- 5 jande: HPV6a L2 (vilket kodas av nukleotider 4380-5804 i sekvens nr 2), HPV6a El (vilket kodas av nukleotider 717-2781 i sekvens nr 2),
10 HPV6a E2 (vilket kodas av nukleotider 2697-3829 i sekvens nr 2), HPVöa E4 (vilket kodas av nukleotider 3242-3584 i sekvens nr 2), HPV6a E5 (vilket kodas av nukleotider 3888-4163 i 15 sekvens nr 2), HPV6a E6 (vilket kodas av nukleotider 32-554 i sekvens nr 2) och HPV6a E7 (vilket kodas av nukleotider 442-826 i sekvens nr 2) , 20 varvid DNA är under transkriptionell kontroll av en hetero-logisk promotor.
2. Vektor, som omfattar ett DNA som kodar ett hu-mant papillomavirus 6a (HPV6a) -protein, varvid DNA:t bestär av en sekvens, som väljs frän en grupp, som bestär av 25 de följande: HPVöa L2 (nukleotider 4380-5804 i sekvens nr 2), HPVöa El (nukleotider 717-2781 i sekvens nr 2), HPVöa E2 (nukleotider 2697-3829 i sekvens nr 2), HPV6a E4 (nukleotider 3242-3584 i sekvens nr 2),
30 HPVöa E5 (nukleotider 3888-4163 i sekvens nr 2), HPV6a E6 (nukleotider 32-554 i sekvens nr 2) och HPV6a E7 (nukleotider 442-826 i sekvens nr 2).
3. Värdcell, som omfattar en vektor enligt patent- krav 2.
4. Värdcell enligt patentkrav 3, vilken väljs frän en grupp som bestär av följande: jäst-, insekt- och dägg- dj ursceller.
5. Värdcell enligt patentkrav 4, vilken är en jäst- 5 cell.
6. Förfarande för uttryckning av ett protein av hu-mant papillomavirus typ 6a i en värd, vilket förfarande om-fattar, att man a) inför en vektor, som omfattar ett DNA, som kodar 10 ett HPV6a-protein, som väljs frän en grupp, som bestär av följande: HPV6a L2 (nukleotider 4380-5804 i sekvens nr 2), HPV6a El (nukleotider 717-2781 i sekvens nr 2), HPVöa E2 (nukleotider 2697-3829 i sekvens nr 2),
15 HPV6a E4 (nukleotider 3242-3584 i sekvens nr 2), HPV6a E5 (nukleotider 3888-4163 i sekvens nr 2), HPV6a E6 (nukleotider 32-554 i sekvens nr 2) och HPV6a E7 (nukleotider 442-826 i sekvens nr 2), och b) odlar värdcellen i förhällanden, vilka tilläter 20 expression av HPVöa-proteinet frän vektorn.
7. Förfarande enligt patentkrav 6, varvid värdcellen väljs frän en grupp, som bestär av följande: jäst-, insekt- och däggdjursceller.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31046894A | 1994-09-22 | 1994-09-22 | |
| US31046894 | 1994-09-22 | ||
| US9511859 | 1995-09-18 | ||
| PCT/US1995/011859 WO1996009375A1 (en) | 1994-09-22 | 1995-09-18 | Dna encoding human papillomavirus type 6a |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI971203A0 FI971203A0 (sv) | 1997-03-21 |
| FI971203A FI971203A (sv) | 1997-03-21 |
| FI121507B true FI121507B (sv) | 2010-12-15 |
Family
ID=23202654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI971203A FI121507B (sv) | 1994-09-22 | 1997-03-21 | DNA-kodande människopapillomavirus typ 6A |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6290965B1 (sv) |
| EP (1) | EP0782615A4 (sv) |
| JP (1) | JPH10506014A (sv) |
| AU (1) | AU694269B2 (sv) |
| BG (1) | BG101338A (sv) |
| BR (1) | BR9509076A (sv) |
| CA (1) | CA2200582C (sv) |
| CZ (1) | CZ87597A3 (sv) |
| FI (1) | FI121507B (sv) |
| HU (1) | HUT77337A (sv) |
| NO (1) | NO971347L (sv) |
| NZ (1) | NZ293461A (sv) |
| PL (1) | PL319294A1 (sv) |
| RU (1) | RU2177999C2 (sv) |
| SK (1) | SK35897A3 (sv) |
| WO (1) | WO1996009375A1 (sv) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6962981B1 (en) * | 1996-03-25 | 2005-11-08 | Medarex, Inc. | Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen |
| GB9621091D0 (en) | 1996-10-09 | 1996-11-27 | Fondation Pour Le Perfectionem | Attenuated microorganisms strains and their uses |
| ES2262333T3 (es) * | 1998-08-14 | 2006-11-16 | MERCK & CO., INC. | Procedimiento para purificar particulas similares a virus de papilomavirus humano. |
| CN1100835C (zh) * | 1998-10-30 | 2003-02-05 | 中国科学院感光化学研究所 | 加入纳米无机化合物粒子的钛溶胶－凝胶涂料及其制法和用途 |
| GB0017990D0 (en) * | 2000-07-21 | 2000-09-13 | Glaxo Group Ltd | Papilloma virus sequences |
| WO2004081178A2 (en) * | 2003-03-06 | 2004-09-23 | Indiana University Research And Technology Corporation | Methods and composition for producing infectious hpv stocks |
| IL156670A0 (en) * | 2003-06-26 | 2004-01-04 | Zvi Zolotariov | Aloe suppositories |
| US20080160040A1 (en) * | 2004-04-15 | 2008-07-03 | Ghim Shin-Je | Plant-produced compositions for treating papillomavirus infection and related methods |
| JP5020825B2 (ja) | 2004-12-08 | 2012-09-05 | ジェン−プローブ・インコーポレーテッド | 複数型のヒトパピローマウイルスに由来する核酸の検出 |
| US8084207B2 (en) * | 2005-03-03 | 2011-12-27 | Ibis Bioscience, Inc. | Compositions for use in identification of papillomavirus |
| US20070031826A1 (en) * | 2005-08-05 | 2007-02-08 | My Gene | Diagnostic kit for determining the genotype of a human papilloma virus and method of using thereof |
| AU2006295040A1 (en) * | 2005-09-08 | 2007-04-05 | Kentucky Bioprocessing, Llc | Modified tobacco mosaic virus particles as scaffolds for display of protein antigens for vaccine applications |
| EP2059262B1 (en) * | 2006-08-28 | 2013-08-21 | Sungkyunkwan University Foundation for Corporate Collaboration | A dna vaccine for treating or preventing cervical cancer comprising a gene encoding hpv protein |
| CA2709894C (en) | 2007-12-21 | 2017-10-24 | Novartis Ag | Mammalian expression vector |
| EP2576840B1 (en) | 2010-05-25 | 2018-10-17 | QIAGEN Gaithersburg, Inc. | Fast results hybrid capture assay and associated strategically-truncated probes |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE380871T1 (de) * | 1992-06-25 | 2007-12-15 | Univ Georgetown | Papillomavirus vakzine |
| SK147696A3 (en) * | 1994-05-16 | 1997-08-06 | Merck & Co Inc | Isolated and purified protein of papillomavirus, a capside, a viral particle, pharmaceutical composition comprising its, a method of making them and their use |
| AR004464A1 (es) * | 1994-11-14 | 1998-12-16 | Merck Sharp & Dohme | Un metodo para producir una proteina de capside de papilomavirus |
| IL117591A0 (en) * | 1995-03-30 | 1996-07-23 | Merck & Co Inc | Synthetic DNA encoding human papillomavirus type 11 L1 protein |
-
1995
- 1995-09-18 NZ NZ293461A patent/NZ293461A/en unknown
- 1995-09-18 EP EP95933148A patent/EP0782615A4/en not_active Ceased
- 1995-09-18 WO PCT/US1995/011859 patent/WO1996009375A1/en not_active Application Discontinuation
- 1995-09-18 CA CA002200582A patent/CA2200582C/en not_active Expired - Lifetime
- 1995-09-18 SK SK358-97A patent/SK35897A3/sk unknown
- 1995-09-18 BR BR9509076A patent/BR9509076A/pt not_active Application Discontinuation
- 1995-09-18 PL PL95319294A patent/PL319294A1/xx unknown
- 1995-09-18 AU AU35918/95A patent/AU694269B2/en not_active Expired
- 1995-09-18 JP JP8511012A patent/JPH10506014A/ja active Pending
- 1995-09-18 RU RU97106340/13A patent/RU2177999C2/ru active
- 1995-09-18 HU HU9702290A patent/HUT77337A/hu unknown
- 1995-09-18 CZ CZ97875A patent/CZ87597A3/cs unknown
-
1997
- 1997-03-18 BG BG101338A patent/BG101338A/xx unknown
- 1997-03-21 NO NO971347A patent/NO971347L/no not_active Application Discontinuation
- 1997-03-21 FI FI971203A patent/FI121507B/sv not_active IP Right Cessation
-
2000
- 2000-03-08 US US09/521,526 patent/US6290965B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH10506014A (ja) | 1998-06-16 |
| MX9702209A (es) | 1997-07-31 |
| AU3591895A (en) | 1996-04-09 |
| CA2200582C (en) | 2007-03-27 |
| CA2200582A1 (en) | 1996-03-28 |
| AU694269B2 (en) | 1998-07-16 |
| PL319294A1 (en) | 1997-08-04 |
| EP0782615A1 (en) | 1997-07-09 |
| FI971203A0 (sv) | 1997-03-21 |
| BR9509076A (pt) | 1998-07-14 |
| WO1996009375A1 (en) | 1996-03-28 |
| HUT77337A (hu) | 1998-03-30 |
| FI971203A (sv) | 1997-03-21 |
| RU2177999C2 (ru) | 2002-01-10 |
| CZ87597A3 (cs) | 1998-01-14 |
| NO971347L (no) | 1997-05-21 |
| US6290965B1 (en) | 2001-09-18 |
| SK35897A3 (en) | 1998-02-04 |
| BG101338A (en) | 1997-10-31 |
| NO971347D0 (no) | 1997-03-21 |
| EP0782615A4 (en) | 2001-08-22 |
| NZ293461A (en) | 1998-04-27 |
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