FI120499B - Förfaranden som anknyter till Grb3-3-gen eller dess varianter - Google Patents
Förfaranden som anknyter till Grb3-3-gen eller dess varianter Download PDFInfo
- Publication number
- FI120499B FI120499B FI961202A FI961202A FI120499B FI 120499 B FI120499 B FI 120499B FI 961202 A FI961202 A FI 961202A FI 961202 A FI961202 A FI 961202A FI 120499 B FI120499 B FI 120499B
- Authority
- FI
- Finland
- Prior art keywords
- grb3
- sequence
- vector
- grb2
- gene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Claims (8)
1. Förfarande för framställning av en vektor, kännetecknat av att tili en lämplig vektor tillsätts 5 en nukleotidsekvens, som representeras av sekvens-id- nummer 1.
2. Förfarande för framställning av en vektor, kännetecknat av att tili den lämpliga vektorn tili" sätts en nukleotidsekvens, som representeras av sekvens- 10 id-nummer 1 och som förmär inhibera ätminstone delvis ex-primering av proteinet Grb2 eller Grb3-3.
3. Förfarande enligt patentkrav 1 eller 2, kännetecknat av att vektorn är en virusvektor.
4. Förfarande enligt patentkrav 3, känneteck- 15 nat av att vektorn har erhällits frän adenovirus, retrovirus, AAV:er HSV-virus, CMV eller kokoppsvaccin.
5. Förfarande enligt patentkrav 3 eller 4, kännetecknat av att vektorn är ett för replikation brist-fälligt virus. 20
6. Förfarande för framställning av en nukleotid sekvens, som representeras av sekvens-id-nummer 1, kännetecknat av att ett lämpligt utgängsmaterial sällas med en sond, som representeras av sekvens-id-nummer 2, och den önskade nukleotidsekvensen isoleras. 25
7. Förfarande för framställning av en nukleotid sekvens, som representeras av sekvens-id-nummer 1 och som förmär inhibera ätminstone delvis exprimering av proteinet Grb2 eller Grb3-3, kännetecknat av att ett lämpligt utgängsmaterial sällas med en lämplig sond och den önskade 30 nukleotidsekvensen isoleras.
8. Förfarande enligt patentkrav 6 eller 7, kännetecknat av att den erhällna nukleotidsekvensen dess-utom komplexeras i DEAE-dextran, tumaproteiner eller lipi-der, som sadan eller vidare inkluderad i liposomer.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9310971 | 1993-09-15 | ||
FR9310971A FR2710074B1 (fr) | 1993-09-15 | 1993-09-15 | Gène GRB3-3, ses variants et leurs utilisations. |
FR9400542 | 1994-05-09 | ||
PCT/FR1994/000542 WO1995007981A1 (fr) | 1993-09-15 | 1994-05-09 | Gene grb3-3, ses variants et leurs utilisations |
Publications (3)
Publication Number | Publication Date |
---|---|
FI961202A FI961202A (sv) | 1996-03-14 |
FI961202A0 FI961202A0 (sv) | 1996-03-14 |
FI120499B true FI120499B (sv) | 2009-11-13 |
Family
ID=9450882
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI961202A FI120499B (sv) | 1993-09-15 | 1996-03-14 | Förfaranden som anknyter till Grb3-3-gen eller dess varianter |
Country Status (27)
Country | Link |
---|---|
US (2) | USRE37952E1 (sv) |
EP (1) | EP0719328B1 (sv) |
JP (1) | JP3794697B2 (sv) |
KR (1) | KR100330477B1 (sv) |
CN (1) | CN1098930C (sv) |
AT (1) | ATE196926T1 (sv) |
AU (1) | AU698819B2 (sv) |
BR (1) | BR9407693A (sv) |
CA (1) | CA2169938A1 (sv) |
CZ (1) | CZ288882B6 (sv) |
DE (1) | DE69426121T2 (sv) |
DK (1) | DK0719328T3 (sv) |
ES (1) | ES2152313T3 (sv) |
FI (1) | FI120499B (sv) |
FR (1) | FR2710074B1 (sv) |
GR (1) | GR3034600T3 (sv) |
HU (1) | HU221516B (sv) |
IL (2) | IL126756A (sv) |
NO (1) | NO319144B1 (sv) |
NZ (1) | NZ266162A (sv) |
PL (1) | PL178402B1 (sv) |
PT (1) | PT719328E (sv) |
RU (1) | RU2159815C2 (sv) |
SK (1) | SK281123B6 (sv) |
UA (1) | UA46715C2 (sv) |
WO (1) | WO1995007981A1 (sv) |
ZA (1) | ZA947059B (sv) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2732348B1 (fr) * | 1995-03-31 | 1997-04-30 | Rhone Poulenc Rorer Sa | Systeme d'expression conditionnel |
US6171800B1 (en) | 1995-06-07 | 2001-01-09 | Biogen, Inc. | Method of making and binding CAIP polypeptides |
US5837844A (en) * | 1995-06-07 | 1998-11-17 | Biogen, Inc. | CAIP-like gene family |
US6423824B1 (en) | 1995-06-07 | 2002-07-23 | Biogen, Inc. | CAIP-like gene family |
US5855911A (en) * | 1995-08-29 | 1999-01-05 | Board Of Regents, The University Of Texas System | Liposomal phosphodiester, phosphorothioate, and P-ethoxy oligonucleotides |
WO1997049808A1 (en) * | 1996-06-27 | 1997-12-31 | Biogen, Inc. | The caip-like gene family |
US7309692B1 (en) * | 1996-07-08 | 2007-12-18 | Board Of Regents, The University Of Texas System | Inhibition of chronic myelogenous leukemic cell growth by liposomal-antisense oligodeoxy-nucleotides targeting to GRB2 or CRK1 |
US6977244B2 (en) * | 1996-10-04 | 2005-12-20 | Board Of Regents, The University Of Texas Systems | Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides |
US7704962B1 (en) | 1997-10-03 | 2010-04-27 | Board Of Regents, The University Of Texas System | Small oligonucleotides with anti-tumor activity |
US7285288B1 (en) | 1997-10-03 | 2007-10-23 | Board Of Regents, The University Of Texas System | Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides |
EP0998945A1 (en) * | 1998-09-30 | 2000-05-10 | Transgene S.A. | Use of magnesium (Mg2+) for the enhancement of gene delivery in gene therapy |
NZ553687A (en) | 2000-03-30 | 2010-03-26 | Whitehead Biomedical Inst | RNA sequence-specific mediators of RNA interference |
EP1873259B1 (en) | 2000-12-01 | 2012-01-25 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | RNA interference mediated by 21 and 22nt RNAs |
WO2003061386A1 (en) * | 2002-01-03 | 2003-07-31 | Board Of Regents, The University Of Texas System | Wt1 antisense oligos for the inhibition of breast cancer |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU667803B2 (en) * | 1991-01-18 | 1996-04-18 | New York University | A receptor tyrosine kinase target protein cDNA cloning method and hGRB proteins |
AU5136093A (en) * | 1992-09-25 | 1994-04-26 | Warner-Lambert Company | Peptide antagonists of sh2 binding and therapeutic uses thereof |
-
1993
- 1993-09-15 FR FR9310971A patent/FR2710074B1/fr not_active Expired - Fee Related
-
1994
- 1994-05-09 AT AT94915598T patent/ATE196926T1/de not_active IP Right Cessation
- 1994-05-09 CA CA002169938A patent/CA2169938A1/fr not_active Abandoned
- 1994-05-09 US US09/641,640 patent/USRE37952E1/en not_active Expired - Fee Related
- 1994-05-09 AU AU67247/94A patent/AU698819B2/en not_active Ceased
- 1994-05-09 DE DE69426121T patent/DE69426121T2/de not_active Expired - Fee Related
- 1994-05-09 JP JP50901595A patent/JP3794697B2/ja not_active Expired - Fee Related
- 1994-05-09 PL PL94313445A patent/PL178402B1/pl not_active IP Right Cessation
- 1994-05-09 WO PCT/FR1994/000542 patent/WO1995007981A1/fr active IP Right Grant
- 1994-05-09 KR KR1019960701323A patent/KR100330477B1/ko not_active IP Right Cessation
- 1994-05-09 CN CN94193814A patent/CN1098930C/zh not_active Expired - Fee Related
- 1994-05-09 SK SK345-96A patent/SK281123B6/sk not_active IP Right Cessation
- 1994-05-09 HU HU9600668A patent/HU221516B/hu not_active IP Right Cessation
- 1994-05-09 US US08/612,857 patent/US5831048A/en not_active Ceased
- 1994-05-09 PT PT94915598T patent/PT719328E/pt unknown
- 1994-05-09 DK DK94915598T patent/DK0719328T3/da active
- 1994-05-09 BR BR9407693A patent/BR9407693A/pt not_active Application Discontinuation
- 1994-05-09 CZ CZ1996758A patent/CZ288882B6/cs not_active IP Right Cessation
- 1994-05-09 UA UA96030994A patent/UA46715C2/uk unknown
- 1994-05-09 EP EP94915598A patent/EP0719328B1/fr not_active Expired - Lifetime
- 1994-05-09 NZ NZ266162A patent/NZ266162A/en not_active IP Right Cessation
- 1994-05-09 RU RU96107888/13A patent/RU2159815C2/ru active
- 1994-05-09 ES ES94915598T patent/ES2152313T3/es not_active Expired - Lifetime
- 1994-09-12 IL IL126756A patent/IL126756A/en not_active IP Right Cessation
- 1994-09-12 IL IL11094294A patent/IL110942A/en not_active IP Right Cessation
- 1994-09-13 ZA ZA947059A patent/ZA947059B/xx unknown
-
1996
- 1996-03-08 NO NO19960965A patent/NO319144B1/no not_active IP Right Cessation
- 1996-03-14 FI FI961202A patent/FI120499B/sv active IP Right Grant
-
2000
- 2000-10-12 GR GR20000401514T patent/GR3034600T3/el not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Transfer of assignment of patent |
Owner name: AVENTIS PHARMA S.A. |
|
FG | Patent granted |
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