FI112361B - Menetelmä terapeuttisesti käyttökelpoisten D-vitamiinin johdannaisten valmistamiseksi - Google Patents
Menetelmä terapeuttisesti käyttökelpoisten D-vitamiinin johdannaisten valmistamiseksi Download PDFInfo
- Publication number
- FI112361B FI112361B FI955316A FI955316A FI112361B FI 112361 B FI112361 B FI 112361B FI 955316 A FI955316 A FI 955316A FI 955316 A FI955316 A FI 955316A FI 112361 B FI112361 B FI 112361B
- Authority
- FI
- Finland
- Prior art keywords
- dihydroxy
- secochola
- group
- homo
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939309422A GB9309422D0 (en) | 1993-05-07 | 1993-05-07 | Chemical compounds |
GB9309422 | 1993-05-07 | ||
GB9400975 | 1994-05-06 | ||
PCT/GB1994/000975 WO1994026707A1 (en) | 1993-05-07 | 1994-05-06 | Vitamin d amide derivatives |
Publications (3)
Publication Number | Publication Date |
---|---|
FI955316A0 FI955316A0 (fi) | 1995-11-06 |
FI955316A FI955316A (fi) | 1995-12-22 |
FI112361B true FI112361B (fi) | 2003-11-28 |
Family
ID=10735089
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI955316A FI112361B (fi) | 1993-05-07 | 1995-11-06 | Menetelmä terapeuttisesti käyttökelpoisten D-vitamiinin johdannaisten valmistamiseksi |
Country Status (20)
Country | Link |
---|---|
US (1) | US5756733A (no) |
EP (1) | EP0696275B1 (no) |
JP (1) | JP3703099B2 (no) |
KR (1) | KR100321414B1 (no) |
CN (1) | CN1093852C (no) |
AT (1) | ATE169617T1 (no) |
AU (1) | AU678246B2 (no) |
CA (1) | CA2162272A1 (no) |
CZ (1) | CZ291238B6 (no) |
DE (1) | DE69412476T2 (no) |
DK (1) | DK0696275T3 (no) |
ES (1) | ES2122275T3 (no) |
FI (1) | FI112361B (no) |
GB (1) | GB9309422D0 (no) |
HU (1) | HUT74165A (no) |
IL (1) | IL109595A (no) |
NO (1) | NO309187B1 (no) |
NZ (1) | NZ265665A (no) |
WO (1) | WO1994026707A1 (no) |
ZA (1) | ZA943162B (no) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9405715D0 (en) * | 1994-03-23 | 1994-05-11 | Res Inst Medicine Chem | Chemical compounds |
MX9709875A (es) * | 1995-06-06 | 1998-03-31 | Pfizer | N-(indol-2-carbonil)-glicinamidas substituidas y derivados como inhibidores de glicogeno fosforilasa, composiciones que las contienen y uso de las mismas. |
DE19619036A1 (de) * | 1996-04-30 | 1997-11-13 | Schering Ag | Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln |
GB9623569D0 (en) * | 1996-11-13 | 1997-01-08 | Immunodiagnostic Systems Ltd | Vitamin D immumoassay systems |
US6043385A (en) * | 1997-12-16 | 2000-03-28 | Hoffman-La Roche Inc. | Vitamin D derivatives |
GB9804861D0 (en) * | 1998-03-06 | 1998-04-29 | Res Inst Medicine Chem | Chemical compounds |
US6531460B1 (en) * | 1998-10-23 | 2003-03-11 | Teijin Limited | Vitamin D, derivatives and remedies for inflammatory respiratory diseases containing the same |
NZ513441A (en) * | 1999-02-08 | 2004-01-30 | Alza Corp | Stable non-aqueous single phase viscous drug delivery vehicles comprising a polymer a solvent and a surfactant |
DE19935771A1 (de) * | 1999-07-23 | 2001-02-01 | Schering Ag | Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln |
NZ517978A (en) | 1999-09-29 | 2003-11-28 | Colotech As | Composition comprising ASA, calcium and 1,25 DHC for the prevention of colorectal cancer |
US6703380B2 (en) | 1999-09-29 | 2004-03-09 | Colotech A/S | Prevention of cancer |
US6989377B2 (en) | 1999-12-21 | 2006-01-24 | Wisconsin Alumni Research Foundation | Treating vitamin D responsive diseases |
US6358939B1 (en) | 1999-12-21 | 2002-03-19 | Northern Lights Pharmaceuticals, Llc | Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease |
CN101462994B (zh) * | 2000-06-15 | 2012-11-28 | 中外制药株式会社 | 维生素d衍生物 |
CA2411409C (en) | 2000-06-15 | 2011-05-17 | Chugai Seiyaku Kabushiki Kaisha | Vitamin d derivatives |
US6277877B1 (en) | 2000-08-15 | 2001-08-21 | Pfizer, Inc. | Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors |
CN1649845A (zh) * | 2002-04-26 | 2005-08-03 | 先灵公司 | 蝇蕈碱拮抗剂 |
WO2007142158A1 (ja) * | 2006-06-02 | 2007-12-13 | Nippon Shinyaku Co., Ltd. | 9,10-セコプレグナン誘導体及び医薬 |
WO2009117831A1 (en) * | 2008-03-27 | 2009-10-01 | The Royal Institution For The Advancement Of Learning/Mcgill University | Hybrid molecules having mixed vitamin d receptor agonism and histone deacetylase inhibitory properties |
CN107019795A (zh) * | 2009-01-27 | 2017-08-08 | 博格有限责任公司 | 用于减轻与化疗有关的副作用的维生素d3化合物 |
MX366076B (es) | 2009-08-14 | 2019-06-27 | Berg Llc | Vitamina d3 y analogos de la misma para tratar alopecia. |
WO2012151058A1 (en) | 2011-05-03 | 2012-11-08 | Wisconsin Alumni Research Foundation | (20s)-24-(p-toluenesulfonyloxy)-25,26,27-trinorvitamin d3 analogs and their uses |
WO2012158794A1 (en) | 2011-05-17 | 2012-11-22 | Wisconsin Alumni Research Foundation | N-cyclopropyl-(20r)-2-methylene-19,26,27-trinor-25-aza-vitamin d analogs and their uses |
NZ714801A (en) | 2013-05-29 | 2021-07-30 | Berg Llc | Preventing or mitigating chemotherapy induced alopecia using vitamin d |
US9338493B2 (en) | 2014-06-30 | 2016-05-10 | Apple Inc. | Intelligent automated assistant for TV user interactions |
US10548908B2 (en) | 2016-09-15 | 2020-02-04 | Nostopharma, LLC | Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8929059D0 (en) * | 1989-12-22 | 1990-02-28 | Leo Pharm Prod Ltd | Chemical compounds |
AU664213B2 (en) * | 1991-11-07 | 1995-11-09 | Research Institute For Medicine And Chemistry Inc. | Vitamin D amide derivatives |
-
1993
- 1993-05-07 GB GB939309422A patent/GB9309422D0/en active Pending
-
1994
- 1994-05-06 JP JP52511994A patent/JP3703099B2/ja not_active Expired - Fee Related
- 1994-05-06 WO PCT/GB1994/000975 patent/WO1994026707A1/en active IP Right Grant
- 1994-05-06 AT AT94914472T patent/ATE169617T1/de not_active IP Right Cessation
- 1994-05-06 CN CN94192435A patent/CN1093852C/zh not_active Expired - Fee Related
- 1994-05-06 DE DE69412476T patent/DE69412476T2/de not_active Expired - Fee Related
- 1994-05-06 EP EP94914472A patent/EP0696275B1/en not_active Expired - Lifetime
- 1994-05-06 CA CA002162272A patent/CA2162272A1/en not_active Abandoned
- 1994-05-06 ES ES94914472T patent/ES2122275T3/es not_active Expired - Lifetime
- 1994-05-06 AU AU66832/94A patent/AU678246B2/en not_active Ceased
- 1994-05-06 DK DK94914472T patent/DK0696275T3/da active
- 1994-05-06 CZ CZ19952903A patent/CZ291238B6/cs not_active IP Right Cessation
- 1994-05-06 ZA ZA943162A patent/ZA943162B/xx unknown
- 1994-05-06 KR KR1019950704980A patent/KR100321414B1/ko not_active IP Right Cessation
- 1994-05-06 NZ NZ265665A patent/NZ265665A/en unknown
- 1994-05-06 US US08/532,799 patent/US5756733A/en not_active Expired - Fee Related
- 1994-05-06 HU HU9503190A patent/HUT74165A/hu unknown
- 1994-05-08 IL IL10959594A patent/IL109595A/xx not_active IP Right Cessation
-
1995
- 1995-11-06 FI FI955316A patent/FI112361B/fi not_active IP Right Cessation
- 1995-11-06 NO NO954426A patent/NO309187B1/no unknown
Also Published As
Publication number | Publication date |
---|---|
CZ291238B6 (cs) | 2003-01-15 |
AU6683294A (en) | 1994-12-12 |
HUT74165A (en) | 1996-11-28 |
DE69412476T2 (de) | 1999-03-11 |
NO954426L (no) | 1996-01-08 |
NO309187B1 (no) | 2000-12-27 |
CZ290395A3 (en) | 1996-06-12 |
ATE169617T1 (de) | 1998-08-15 |
FI955316A0 (fi) | 1995-11-06 |
JPH08509971A (ja) | 1996-10-22 |
AU678246B2 (en) | 1997-05-22 |
EP0696275B1 (en) | 1998-08-12 |
WO1994026707A1 (en) | 1994-11-24 |
HU9503190D0 (en) | 1996-01-29 |
US5756733A (en) | 1998-05-26 |
NO954426D0 (no) | 1995-11-06 |
CA2162272A1 (en) | 1994-11-24 |
JP3703099B2 (ja) | 2005-10-05 |
IL109595A (en) | 1999-04-11 |
ZA943162B (en) | 1995-04-13 |
NZ265665A (en) | 1997-05-26 |
IL109595A0 (en) | 1994-08-26 |
DK0696275T3 (da) | 1998-11-09 |
FI955316A (fi) | 1995-12-22 |
ES2122275T3 (es) | 1998-12-16 |
CN1125436A (zh) | 1996-06-26 |
CN1093852C (zh) | 2002-11-06 |
EP0696275A1 (en) | 1996-02-14 |
GB9309422D0 (en) | 1993-06-23 |
KR100321414B1 (ko) | 2002-12-05 |
DE69412476D1 (de) | 1998-09-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MA | Patent expired |