FI109907B - Menetelmä ginkgolidi B:n valmistamiseksi ginkgolidi C:stä - Google Patents

Menetelmä ginkgolidi B:n valmistamiseksi ginkgolidi C:stä Download PDF

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Publication number
FI109907B
FI109907B FI951903A FI951903A FI109907B FI 109907 B FI109907 B FI 109907B FI 951903 A FI951903 A FI 951903A FI 951903 A FI951903 A FI 951903A FI 109907 B FI109907 B FI 109907B
Authority
FI
Finland
Prior art keywords
ginkgolide
process according
reaction
borohydride
carried out
Prior art date
Application number
FI951903A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI951903A0 (fi
FI951903A (fi
Inventor
Jean-Bernard Cazaux
Michel Dafniet
Jacques Rebollo
Beng-Poon Teng
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of FI951903A0 publication Critical patent/FI951903A0/fi
Publication of FI951903A publication Critical patent/FI951903A/fi
Application granted granted Critical
Publication of FI109907B publication Critical patent/FI109907B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
FI951903A 1994-04-22 1995-04-21 Menetelmä ginkgolidi B:n valmistamiseksi ginkgolidi C:stä FI109907B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9408044A GB9408044D0 (en) 1994-04-22 1994-04-22 Conversion of ginkgolide c to ginkgolide b
GB9408044 1994-04-22

Publications (3)

Publication Number Publication Date
FI951903A0 FI951903A0 (fi) 1995-04-21
FI951903A FI951903A (fi) 1995-10-23
FI109907B true FI109907B (fi) 2002-10-31

Family

ID=10753985

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951903A FI109907B (fi) 1994-04-22 1995-04-21 Menetelmä ginkgolidi B:n valmistamiseksi ginkgolidi C:stä

Country Status (23)

Country Link
US (1) US5599950A (no)
EP (1) EP0680968B1 (no)
JP (1) JP2992575B2 (no)
KR (1) KR950032203A (no)
AT (1) ATE189817T1 (no)
AU (1) AU684338B2 (no)
CA (1) CA2147423C (no)
DE (1) DE69515077T2 (no)
DK (1) DK0680968T3 (no)
DZ (1) DZ1874A1 (no)
ES (1) ES2144585T3 (no)
FI (1) FI109907B (no)
FR (1) FR2719046B1 (no)
GB (2) GB9408044D0 (no)
IE (1) IE80950B1 (no)
MY (1) MY113056A (no)
NO (1) NO310557B1 (no)
NZ (1) NZ270925A (no)
OA (1) OA10145A (no)
RU (1) RU2145326C1 (no)
TN (1) TNSN95041A1 (no)
TW (1) TW300897B (no)
ZA (1) ZA952986B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981902A (en) * 1994-12-15 1999-11-09 Mitsubishi Chemical Corporation Texturing apparatus for magnetic recording medium and magnetic recording medium process thereby
AU4981397A (en) * 1996-10-16 1998-05-11 Merck & Co., Inc. Triterpene derivatives with immunosupressant activity
WO1998016532A1 (en) * 1996-10-16 1998-04-23 Merck & Co., Inc. Triterpene derivatives with immunosuppressant activity
US6100293A (en) * 1997-10-17 2000-08-08 Merck & Co., Inc. Tetracyclic triterpene derivatives with immunosuppressant activity
US6083980A (en) * 1997-10-17 2000-07-04 Merck & Co., Inc. Furanyl, tetracyclic triterpene derivatives with immunosuppressant activity
US6022890A (en) * 1997-11-14 2000-02-08 Merck & Co., Inc. Immunosuppressant tetracyclic triterpenes
US6030621A (en) 1998-03-19 2000-02-29 De Long; Xie Ginkgo biloba composition, method to prepare the same and uses thereof
US6051590A (en) * 1999-05-13 2000-04-18 Merck & Co., Inc. Immunosuppressant tricyclic compounds
US6946283B2 (en) * 2001-01-05 2005-09-20 William Marsh Rice University Ginkgo biloba levopimaradiene synthase
US7238514B2 (en) * 2001-01-05 2007-07-03 William Marsh Rice University Diterpene-producing unicellular organism
FR2823116B1 (fr) * 2001-04-10 2004-11-19 Sod Conseils Rech Applic Procede de preparation d'une extrait de feuilles de ginkgo biloba hautement enrichi en principes actifs
US6693091B2 (en) 2002-03-29 2004-02-17 The Trustees Of Columbia University In The City Of New York Analogs of terpene trilactones from Ginkgo biloba for bioorganic and imaging studies
WO2003082185A2 (en) * 2002-03-29 2003-10-09 The Trustees Of Columbia University In The City Of New York Analogs of terpene trilactones from ginkgo biloba and related compounds and uses thereof
WO2005021496A2 (en) * 2003-08-27 2005-03-10 The Trustees Of Columbia University In The City Of New York Synthesis of derivatives of ginkgolide c
US7763741B2 (en) 2003-11-12 2010-07-27 The Trustees Of Columbia University In The City Of New York Separation of ginkgolides and bilobalide from G. biloba
WO2005092324A1 (en) * 2004-03-19 2005-10-06 The Trustees Of Columbia University In The City Of New York Ginkgolide compounds, compositions, extracts, and uses thereof
US20080306145A1 (en) * 2004-11-23 2008-12-11 The Trustees Of Columbia University In The City Of New York Preparation Of Ginkgolide And F-Seco-Ginkgolide Lactols
US20090221019A1 (en) * 2005-06-22 2009-09-03 Koji Nakanishi Core-Modified Terpene Trilactones From Ginkgo Biloba Extract and Biological Evaluation Thereof
CN102382121A (zh) * 2010-09-02 2012-03-21 秦引林 银杏内酯衍生物及其在制药中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8418424D0 (en) * 1984-07-19 1984-08-22 Scras Inhibition of platelets aggregation
KR940002795B1 (ko) * 1989-06-16 1994-04-02 주식회사 선경인더스트리 은행잎에서 징코라이드를 분리 및 정제하는 방법
GB9107425D0 (en) * 1991-04-09 1991-05-22 Scras Preparation of ginkgolide b

Also Published As

Publication number Publication date
ES2144585T3 (es) 2000-06-16
NZ270925A (en) 1996-03-26
JPH07291975A (ja) 1995-11-07
NO951524D0 (no) 1995-04-21
NO310557B1 (no) 2001-07-23
AU684338B2 (en) 1997-12-11
CA2147423A1 (en) 1995-10-23
RU2145326C1 (ru) 2000-02-10
FI951903A0 (fi) 1995-04-21
OA10145A (fr) 1996-12-18
GB9408044D0 (en) 1994-06-15
ATE189817T1 (de) 2000-03-15
JP2992575B2 (ja) 1999-12-20
EP0680968A1 (fr) 1995-11-08
DE69515077D1 (de) 2000-03-23
US5599950A (en) 1997-02-04
EP0680968B1 (fr) 2000-02-16
CA2147423C (en) 2005-06-21
GB9507801D0 (en) 1995-05-31
FR2719046A1 (fr) 1995-10-27
IE950265A1 (en) 1995-11-01
DZ1874A1 (fr) 2002-02-17
GB2288599A (en) 1995-10-25
AU1656695A (en) 1995-11-02
FI951903A (fi) 1995-10-23
GB2288599B (en) 1998-04-22
MY113056A (en) 2001-11-30
DE69515077T2 (de) 2000-09-14
FR2719046B1 (fr) 1999-03-19
DK0680968T3 (da) 2000-07-31
ZA952986B (en) 1995-12-21
IE80950B1 (en) 1999-07-14
KR950032203A (ko) 1995-12-20
TW300897B (no) 1997-03-21
TNSN95041A1 (fr) 1996-02-06
RU95106678A (ru) 1997-01-10
NO951524L (no) 1995-10-23

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Owner name: IPSEN PHARMA S.A.S.

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