FI107878B - Farmaseuttinen menetelmä - Google Patents

Farmaseuttinen menetelmä Download PDF

Info

Publication number
FI107878B
FI107878B FI941046A FI941046A FI107878B FI 107878 B FI107878 B FI 107878B FI 941046 A FI941046 A FI 941046A FI 941046 A FI941046 A FI 941046A FI 107878 B FI107878 B FI 107878B
Authority
FI
Finland
Prior art keywords
weight
isobutylphenyl
propionic acid
starch
ibuprofen
Prior art date
Application number
FI941046A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI941046A7 (fi
FI941046A0 (fi
Inventor
Graham John Atkin
Peter Drew
John Leslie Turner
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of FI941046A7 publication Critical patent/FI941046A7/fi
Publication of FI941046A0 publication Critical patent/FI941046A0/fi
Application granted granted Critical
Publication of FI107878B publication Critical patent/FI107878B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
FI941046A 1991-09-06 1994-03-04 Farmaseuttinen menetelmä FI107878B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9119052 1991-09-06
GB919119052A GB9119052D0 (en) 1991-09-06 1991-09-06 Pharmaceutical compositions
PCT/EP1992/001953 WO1993004676A1 (en) 1991-09-06 1992-08-25 High content ibuprofen agglomerates and process to prepare them
EP9201953 1992-08-25

Publications (3)

Publication Number Publication Date
FI941046A7 FI941046A7 (fi) 1994-03-04
FI941046A0 FI941046A0 (fi) 1994-03-04
FI107878B true FI107878B (fi) 2001-10-31

Family

ID=10700981

Family Applications (1)

Application Number Title Priority Date Filing Date
FI941046A FI107878B (fi) 1991-09-06 1994-03-04 Farmaseuttinen menetelmä

Country Status (16)

Country Link
US (1) US5512302A (cg-RX-API-DMAC7.html)
EP (1) EP0602112B1 (cg-RX-API-DMAC7.html)
JP (1) JP3444597B2 (cg-RX-API-DMAC7.html)
KR (1) KR100253046B1 (cg-RX-API-DMAC7.html)
AT (1) ATE353213T1 (cg-RX-API-DMAC7.html)
AU (1) AU655673B2 (cg-RX-API-DMAC7.html)
CA (1) CA2116956C (cg-RX-API-DMAC7.html)
CZ (1) CZ282271B6 (cg-RX-API-DMAC7.html)
DE (1) DE69233678T2 (cg-RX-API-DMAC7.html)
FI (1) FI107878B (cg-RX-API-DMAC7.html)
GB (1) GB9119052D0 (cg-RX-API-DMAC7.html)
IL (1) IL103005A (cg-RX-API-DMAC7.html)
IN (1) IN174169B (cg-RX-API-DMAC7.html)
RU (1) RU2123841C1 (cg-RX-API-DMAC7.html)
WO (1) WO1993004676A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA926709B (cg-RX-API-DMAC7.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI101039B (fi) * 1992-10-09 1998-04-15 Eeva Kristoffersson Menetelmä lääkepellettien valmistamiseksi
DE19814256A1 (de) * 1998-03-31 1999-10-07 Asta Medica Ag Feste, schnellzerfallende Cetirizin-Formulierungen
HUP0104606A3 (en) * 1998-12-18 2003-01-28 Basf Ag A pharmaceutical mixture comprising a profen
US6726929B1 (en) 1998-12-18 2004-04-27 Basf Aktiengesellschaft Pharmaceutical mixture comprising a profen
US6251945B1 (en) * 1999-01-14 2001-06-26 Knoll Aktiengesellschaft Pharmaceutical mixture comprising a combination of a profen and other active compounds
DE19901692C2 (de) * 1999-01-18 2002-06-20 Gruenenthal Gmbh Verfahren zur Herstellung von Pellets mit einem Gehalt von bis zu 90 Gew.% eines pharmazeutischen Wirkstoffes
DE10003757A1 (de) * 2000-01-28 2001-08-02 Knoll Ag Ibuprofen-Wirkstoffzubereitung
RU2164796C1 (ru) * 2000-05-25 2001-04-10 Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" Противогистаминное средство и способ его получения
US6962715B2 (en) * 2001-10-24 2005-11-08 Hewlett-Packard Development Company, L.P. Method and dosage form for dispensing a bioactive substance
US20040173146A1 (en) * 2001-06-07 2004-09-09 Figueroa Iddys D. Application of a bioactive agent to a delivery substrate
US20040173147A1 (en) * 2001-06-07 2004-09-09 Figueroa Iddys D. Application of a bioactive agent to a delivery substrate
DE10153934A1 (de) * 2001-11-06 2003-05-22 Basf Ag Verfahren zur Kristallisation von Profenen
GB0312419D0 (en) * 2003-05-30 2003-07-02 Boots Healthcare Int Ltd Use of a compound in the treatment of sleep disorders and the like, in providing refreshedness on waking and a method for the treatment of grogginess
RU2254854C2 (ru) * 2003-09-08 2005-06-27 Открытое акционерное общество "Акционерное курганское общество медицинских препаратов и изделий "Синтез" Анальгезирующий, жаропонижающий, противовоспалительный препарат и способ его получения
US20050203482A1 (en) * 2004-03-15 2005-09-15 Chinea Vanessa I. Pharmaceutical dispensing apparatus and method
US20050202051A1 (en) * 2004-03-15 2005-09-15 Chinea Vanessa I. Pharmaceutical vehicle
JP2008266270A (ja) * 2007-04-25 2008-11-06 Kowa Co イブプロフェン、トラネキサム酸及び糖アルコールを含有する固形製剤
PT3220916T (pt) 2014-11-17 2023-06-26 Eisai R&D Man Co Ltd Método para tratamento de cancro com n-((4,6-dimetil-2-oxo-1,2-di-hidropiridina-3-il)metil)-5-(etil(tetrahidro-2h-piran-4-il) amino)-4-metil-4'-(morfolinometil)-[1,1'-bifenilo]-3-carboxamida

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2058288T3 (es) * 1987-07-08 1994-11-01 American Home Prod Composiciones de ibuprofen secadas por atomizacion.
US5240712A (en) * 1987-07-17 1993-08-31 The Boots Company Plc Therapeutic agents
US4837031A (en) * 1987-09-17 1989-06-06 Mallinckrodt, Inc. Compositions containing ibuprofen
US4911921A (en) * 1989-02-02 1990-03-27 Mallinckrodt, Inc. High ibuprofen content granulations
US5266723A (en) * 1989-05-16 1993-11-30 Medice, Ltd., Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg Process for the preparation of optically active 2-aryl-alkanoic acids, especially 2-aryl-propionic acids
US5087454A (en) * 1990-07-30 1992-02-11 American Home Products Corporation Ibuprofen tablet
US5260337A (en) * 1992-07-29 1993-11-09 Merck & Co., Inc. Ibuprofen-muscle relaxant combinations
US5332834A (en) * 1992-12-02 1994-07-26 Hoechst Celanese Corporation Racemization of an enantomerically enriched α-aryl carboxylic acid

Also Published As

Publication number Publication date
WO1993004676A1 (en) 1993-03-18
DE69233678T2 (de) 2008-01-24
JPH06510532A (ja) 1994-11-24
IL103005A0 (en) 1993-01-31
EP0602112B1 (en) 2007-02-07
EP0602112A1 (en) 1994-06-22
CA2116956A1 (en) 1993-03-18
AU655673B2 (en) 1995-01-05
ATE353213T1 (de) 2007-02-15
US5512302A (en) 1996-04-30
GB9119052D0 (en) 1991-10-23
AU2487092A (en) 1993-04-05
DE69233678D1 (de) 2007-03-22
FI941046A7 (fi) 1994-03-04
KR100253046B1 (ko) 2000-05-01
CA2116956C (en) 2002-07-16
CZ49994A3 (en) 1994-07-13
RU2123841C1 (ru) 1998-12-27
ZA926709B (en) 1993-04-28
FI941046A0 (fi) 1994-03-04
IN174169B (cg-RX-API-DMAC7.html) 1994-10-01
CZ282271B6 (cs) 1997-06-11
IL103005A (en) 1996-01-19
JP3444597B2 (ja) 2003-09-08

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Owner name: RECKITT BENCKISER HEALTHCARE (UK) LIMITED

Free format text: RECKITT BENCKISER HEALTHCARE (UK) LIMITED