FI103974B1 - Menetelmä proteiinin puhdistamiseksi - Google Patents

Menetelmä proteiinin puhdistamiseksi

Info

Publication number
FI103974B1
FI103974B1 FI902017A FI902017A FI103974B1 FI 103974 B1 FI103974 B1 FI 103974B1 FI 902017 A FI902017 A FI 902017A FI 902017 A FI902017 A FI 902017A FI 103974 B1 FI103974 B1 FI 103974B1
Authority
FI
Finland
Prior art keywords
disclosed
purifying
protein
technique
impurities
Prior art date
Application number
FI902017A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI902017A0 (fi
FI103974B (fi
Inventor
David Naveh
John Chu-Tay Tang
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22340970&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI103974(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of FI902017A0 publication Critical patent/FI902017A0/fi
Application granted granted Critical
Publication of FI103974B publication Critical patent/FI103974B/fi
Publication of FI103974B1 publication Critical patent/FI103974B1/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/26—Cation exchangers for chromatographic processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
FI902017A 1987-10-23 1990-04-23 Menetelmä proteiinin puhdistamiseksi FI103974B1 (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11188687A 1987-10-23 1987-10-23
US11188687 1987-10-23
US8803589 1988-10-19
PCT/US1988/003589 WO1989003840A1 (en) 1987-10-23 1988-10-19 Method of purifying protein

Publications (3)

Publication Number Publication Date
FI902017A0 FI902017A0 (fi) 1990-04-23
FI103974B FI103974B (fi) 1999-10-29
FI103974B1 true FI103974B1 (fi) 1999-10-29

Family

ID=22340970

Family Applications (1)

Application Number Title Priority Date Filing Date
FI902017A FI103974B1 (fi) 1987-10-23 1990-04-23 Menetelmä proteiinin puhdistamiseksi

Country Status (21)

Country Link
EP (2) EP0313343B2 (es)
JP (1) JPH0788395B2 (es)
KR (1) KR930008447B1 (es)
CN (1) CN1031943C (es)
AT (1) ATE121418T1 (es)
AU (1) AU626008B2 (es)
DE (1) DE3853610T3 (es)
DK (1) DK99690D0 (es)
ES (1) ES2070855T5 (es)
FI (1) FI103974B1 (es)
HU (1) HU204537B (es)
IE (1) IE72219B1 (es)
IL (1) IL88118A (es)
MY (1) MY108512A (es)
NO (1) NO303451B1 (es)
NZ (1) NZ226651A (es)
OA (1) OA09787A (es)
PT (1) PT88813B (es)
TN (1) TNSN88111A1 (es)
WO (1) WO1989003840A1 (es)
ZA (1) ZA887862B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0719860B1 (en) * 1988-05-13 2009-12-16 Amgen Inc. Process for isolating and purifying G-CSF
US7217689B1 (en) 1989-10-13 2007-05-15 Amgen Inc. Glycosylation analogs of erythropoietin
US5110913A (en) * 1990-05-25 1992-05-05 Miles Inc. Antibody purification method
US5463029A (en) * 1992-11-23 1995-10-31 Immunex Corporation Purification of fusion proteins comprising GM-CSF and IL-3
WO1995007703A1 (en) * 1993-09-15 1995-03-23 Alpha Therapeutic Corp. Alpha1-acid glycoprotein purification process and product
US5808011A (en) * 1996-07-01 1998-09-15 Biopure Corporation Method for chromatographic removal of prions
US7304150B1 (en) 1998-10-23 2007-12-04 Amgen Inc. Methods and compositions for the prevention and treatment of anemia
DE60005806T2 (de) 1999-04-08 2004-08-05 Genentech, Inc., South San Francisco Zusammensetzung auf basis gegensätzlich geladener polypeptide
CN100522989C (zh) 2002-09-11 2009-08-05 中外制药株式会社 纯化蛋白质的方法
DE10360841A1 (de) * 2003-12-20 2005-07-14 Henkel Kgaa Helle, stabile, staub- und geruchsarme Enzymgranulate
ES2797480T3 (es) * 2005-03-11 2020-12-02 Wyeth Llc Un procedimiento de cromatografía de reparto débil
SE529259C2 (sv) * 2005-08-31 2007-06-12 Ge Healthcare Bio Sciences Ab Tillverkning av kromarografimatriser, en kromarografimatris, en vätskekromatografikolonn, prcess för att isolera målföreningar och användning av en kromarografimatris för vätskekromatografi
WO2008055310A1 (en) * 2006-11-10 2008-05-15 Murray Goulburn Co-Operative Co. Limited Process for the preparation of angiogenin
CN101556260B (zh) * 2009-05-25 2012-01-11 北京理工大学 固定化pH梯度毛细管等电聚焦测定微生物等电点的方法
CN101556261B (zh) * 2009-05-25 2012-01-11 北京理工大学 微管内等电聚焦和剪断吹出培养测定微生物等电点的方法
WO2013075740A1 (en) * 2011-11-23 2013-05-30 Sanofi Antibody purification method
JP6605202B2 (ja) * 2011-12-22 2019-11-13 ジェネンテック， インコーポレイテッド イオン交換膜クロマトグラフィー
TWI631132B (zh) 2013-05-06 2018-08-01 賽諾菲公司 用於純化抗體之連續多步驟方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4658018A (en) * 1984-03-13 1987-04-14 Immunex Corporation Process for producing homogeneous colony stimulating factor
IL76360A0 (en) * 1984-09-26 1986-01-31 Takeda Chemical Industries Ltd Mutual separation of proteins
ZA872781B (en) * 1986-05-19 1987-10-05 Immunology Ventures B-cell stimulating factor

Also Published As

Publication number Publication date
AU2624788A (en) 1989-05-23
JPH0788395B2 (ja) 1995-09-27
IL88118A (en) 1993-06-10
ES2070855T3 (es) 1995-06-16
AU626008B2 (en) 1992-07-23
DK99690A (da) 1990-04-23
MY108512A (en) 1996-10-31
OA09787A (en) 1994-04-15
IE72219B1 (en) 1997-04-09
DE3853610T3 (de) 2004-05-13
FI902017A0 (fi) 1990-04-23
DE3853610D1 (de) 1995-05-24
DK99690D0 (da) 1990-04-23
FI103974B (fi) 1999-10-29
NZ226651A (en) 1990-09-26
KR890701618A (ko) 1989-12-22
TNSN88111A1 (fr) 1990-07-10
EP0313343B2 (en) 2003-07-23
PT88813B (pt) 1993-01-29
DE3853610T2 (de) 1995-08-31
EP0391934A1 (en) 1990-10-17
NO303451B1 (no) 1998-07-13
ES2070855T5 (es) 2004-03-01
ZA887862B (en) 1989-06-28
IE883168L (en) 1989-04-23
EP0313343B1 (en) 1995-04-19
EP0313343A1 (en) 1989-04-26
HU886264D0 (en) 1990-07-28
CN1032661A (zh) 1989-05-03
NO901769L (no) 1990-04-20
JPH03500649A (ja) 1991-02-14
ATE121418T1 (de) 1995-05-15
KR930008447B1 (ko) 1993-09-04
IL88118A0 (en) 1989-06-30
HU204537B (en) 1992-01-28
WO1989003840A1 (en) 1989-05-05
NO901769D0 (no) 1990-04-20
CN1031943C (zh) 1996-06-05
HUT52783A (en) 1990-08-28

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: SCHERING CORPORATION