FI102191B1 - Menetelmä 3-des-hydroksikystatiini C:n tuottamiseksi ja menetelmässä käytettävä DNA-sekvenssi - Google Patents

Menetelmä 3-des-hydroksikystatiini C:n tuottamiseksi ja menetelmässä käytettävä DNA-sekvenssi

Info

Publication number
FI102191B1
FI102191B1 FI895553A FI895553A FI102191B1 FI 102191 B1 FI102191 B1 FI 102191B1 FI 895553 A FI895553 A FI 895553A FI 895553 A FI895553 A FI 895553A FI 102191 B1 FI102191 B1 FI 102191B1
Authority
FI
Finland
Prior art keywords
dehydroxycstatin
producing
dna sequence
cystatin
modified
Prior art date
Application number
FI895553A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI895553A0 (fi
FI102191B (fi
Inventor
Anders Grubb
Aake Lundwall
Magnus Abrahamson
Henrik Dalboege
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of FI895553A0 publication Critical patent/FI895553A0/fi
Application granted granted Critical
Publication of FI102191B publication Critical patent/FI102191B/fi
Publication of FI102191B1 publication Critical patent/FI102191B1/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI895553A 1987-05-22 1989-11-21 Menetelmä 3-des-hydroksikystatiini C:n tuottamiseksi ja menetelmässä käytettävä DNA-sekvenssi FI102191B1 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK260987A DK260987D0 (da) 1987-05-22 1987-05-22 Fremgangsmaade til fremstilling af et humant protein samt dna-sekvens til anvendelse ved udoevelse af fremgangsmaaden
PCT/DK1988/000082 WO1988009384A1 (fr) 1987-05-22 1988-05-20 Procede de production de cystatine c ou modifications de la cystatine et sequence d'adn destinee a etre utilisee lors de la realisation dudit procede

Publications (3)

Publication Number Publication Date
FI895553A0 FI895553A0 (fi) 1989-11-21
FI102191B FI102191B (fi) 1998-10-30
FI102191B1 true FI102191B1 (fi) 1998-10-30

Family

ID=8113675

Family Applications (1)

Application Number Title Priority Date Filing Date
FI895553A FI102191B1 (fi) 1987-05-22 1989-11-21 Menetelmä 3-des-hydroksikystatiini C:n tuottamiseksi ja menetelmässä käytettävä DNA-sekvenssi

Country Status (12)

Country Link
EP (1) EP0362259B1 (fr)
JP (1) JP3011274B2 (fr)
AT (1) ATE135049T1 (fr)
AU (1) AU619750B2 (fr)
CA (1) CA1340862C (fr)
DE (1) DE3855078T2 (fr)
DK (1) DK260987D0 (fr)
ES (1) ES2013337A6 (fr)
FI (1) FI102191B1 (fr)
IL (1) IL86476A (fr)
NO (1) NO301985B1 (fr)
WO (1) WO1988009384A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2002820A1 (fr) * 1988-11-18 1990-05-18 Kazunori Hanada Utilisation des cystatines en pharmacie
GB9122051D0 (en) * 1991-10-17 1991-11-27 Univ Nottingham Medicines
GB9403819D0 (en) * 1994-02-28 1994-04-20 Univ Leeds Control of parasites
RU2182598C2 (ru) * 1994-11-21 2002-05-20 Новартис Аг Модифицированные ингибиторы протеиназы
AU738766B2 (en) * 1994-11-21 2001-09-27 University Of Leeds, The Modified proteinase inhibitors
EP0842187A4 (fr) * 1995-06-05 2000-04-12 Human Genome Sciences Inc Cystatine e humaine
US6011012A (en) 1995-06-05 2000-01-04 Human Genome Sciences, Inc. Human cystatin E
EP1123399A2 (fr) * 1998-08-05 2001-08-16 The University Of British Columbia Production et utilisation de cystatines modifiees
US6436389B1 (en) * 1998-12-11 2002-08-20 The Salk Institute For Biological Studies Stimulation of cell proliferation by glycosylated cystatin C
EP1176200A3 (fr) 2000-06-20 2005-01-12 Switch Biotech Aktiengesellschaft Utilisation des polypeptides ou leurs acides nucléiques pour le diagnose ou traitement des maladies de la peau ou de la cicatrisation de blessures et leurs utilisations pour l'identification des substances pharmacologiquement actives
EP2880994B1 (fr) * 2012-07-31 2017-06-28 Megmilk Snow Brand Co. Ltd. Nouvelle substance protéique
CN102895658A (zh) * 2012-08-23 2013-01-30 苏州大学附属第一医院 Cystatin C在治疗蛛网膜下腔出血后发生的脑血管痉挛的应用
CN106119286A (zh) * 2016-08-10 2016-11-16 吴江近岸蛋白质科技有限公司 表达载体及其高效表达和制备人胱抑素c蛋白的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775624A (en) * 1985-02-08 1988-10-04 Eli Lilly And Company Vectors and compounds for expression of human protein C

Also Published As

Publication number Publication date
DE3855078T2 (de) 1996-07-18
NO301985B1 (no) 1998-01-05
JP3011274B2 (ja) 2000-02-21
WO1988009384A1 (fr) 1988-12-01
IL86476A0 (en) 1988-11-15
AU619750B2 (en) 1992-02-06
FI895553A0 (fi) 1989-11-21
IL86476A (en) 1994-01-25
ES2013337A6 (es) 1990-05-01
JPH03501201A (ja) 1991-03-22
EP0362259B1 (fr) 1996-03-06
ATE135049T1 (de) 1996-03-15
NO890260L (no) 1989-01-20
EP0362259A1 (fr) 1990-04-11
DK260987D0 (da) 1987-05-22
AU1939988A (en) 1988-12-21
NO890260D0 (no) 1989-01-20
FI102191B (fi) 1998-10-30
DE3855078D1 (de) 1996-04-11
CA1340862C (fr) 1999-12-28

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Owner name: DAKO A/S

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