FI102191B1 - Förfarande för producering av 3-deshydroxicystatin C och en DNA-sekvens för användning vid förfarandet - Google Patents

Förfarande för producering av 3-deshydroxicystatin C och en DNA-sekvens för användning vid förfarandet

Info

Publication number
FI102191B1
FI102191B1 FI895553A FI895553A FI102191B1 FI 102191 B1 FI102191 B1 FI 102191B1 FI 895553 A FI895553 A FI 895553A FI 895553 A FI895553 A FI 895553A FI 102191 B1 FI102191 B1 FI 102191B1
Authority
FI
Finland
Prior art keywords
dehydroxycstatin
producing
dna sequence
cystatin
modified
Prior art date
Application number
FI895553A
Other languages
English (en)
Finnish (fi)
Other versions
FI895553A0 (fi
FI102191B (sv
Inventor
Anders Grubb
Aake Lundwall
Magnus Abrahamson
Henrik Dalboege
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of FI895553A0 publication Critical patent/FI895553A0/fi
Application granted granted Critical
Publication of FI102191B1 publication Critical patent/FI102191B1/sv
Publication of FI102191B publication Critical patent/FI102191B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Electronic Switches (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI895553A 1987-05-22 1989-11-21 Förfarande för producering av 3-deshydroxicystatin C och en DNA-sekven s för användning vid förfarandet FI102191B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK260987A DK260987D0 (da) 1987-05-22 1987-05-22 Fremgangsmaade til fremstilling af et humant protein samt dna-sekvens til anvendelse ved udoevelse af fremgangsmaaden
PCT/DK1988/000082 WO1988009384A1 (en) 1987-05-22 1988-05-20 Method of producing cystatin c or modifications hereof and dna-sequence for use when carrying out the method

Publications (3)

Publication Number Publication Date
FI895553A0 FI895553A0 (fi) 1989-11-21
FI102191B1 true FI102191B1 (sv) 1998-10-30
FI102191B FI102191B (sv) 1998-10-30

Family

ID=8113675

Family Applications (1)

Application Number Title Priority Date Filing Date
FI895553A FI102191B (sv) 1987-05-22 1989-11-21 Förfarande för producering av 3-deshydroxicystatin C och en DNA-sekven s för användning vid förfarandet

Country Status (12)

Country Link
EP (1) EP0362259B1 (sv)
JP (1) JP3011274B2 (sv)
AT (1) ATE135049T1 (sv)
AU (1) AU619750B2 (sv)
CA (1) CA1340862C (sv)
DE (1) DE3855078T2 (sv)
DK (1) DK260987D0 (sv)
ES (1) ES2013337A6 (sv)
FI (1) FI102191B (sv)
IL (1) IL86476A (sv)
NO (1) NO301985B1 (sv)
WO (1) WO1988009384A1 (sv)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2002820A1 (en) * 1988-11-18 1990-05-18 Kazunori Hanada Pharmaceutical use for cystatins
GB9122051D0 (en) * 1991-10-17 1991-11-27 Univ Nottingham Medicines
GB9403819D0 (en) * 1994-02-28 1994-04-20 Univ Leeds Control of parasites
AU738766B2 (en) * 1994-11-21 2001-09-27 University Of Leeds, The Modified proteinase inhibitors
WO1996016173A2 (en) * 1994-11-21 1996-05-30 The University Of Leeds Modified proteinase inhibitors
WO1996039418A1 (en) * 1995-06-05 1996-12-12 Human Genome Sciences, Inc. Human cystatin e
US6011012A (en) 1995-06-05 2000-01-04 Human Genome Sciences, Inc. Human cystatin E
AU5144299A (en) * 1998-08-05 2000-02-28 University Of British Columbia, The Production and use of modified cystatins
CA2354378A1 (en) * 1998-12-11 2000-06-15 The Salk Institute For Biological Studies Co-factors for trophic factors, and methods of use thereof
EP1176200A3 (de) 2000-06-20 2005-01-12 Switch Biotech Aktiengesellschaft Verwendung von Polypeptiden oder diese kodierende Nukleinsäuren zur Diagnose oder Behandlung von Hauterkrankung oder Wundheilung sowie ihre Verwendung zur Indentifizierung von pharmakologisch aktiven Substanzen
SG11201500445SA (en) * 2012-07-31 2015-04-29 Megmilk Snow Brand Co Ltd Novel protein material
CN102895658A (zh) * 2012-08-23 2013-01-30 苏州大学附属第一医院 Cystatin C在治疗蛛网膜下腔出血后发生的脑血管痉挛的应用
CN106119286A (zh) * 2016-08-10 2016-11-16 吴江近岸蛋白质科技有限公司 表达载体及其高效表达和制备人胱抑素c蛋白的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775624A (en) * 1985-02-08 1988-10-04 Eli Lilly And Company Vectors and compounds for expression of human protein C

Also Published As

Publication number Publication date
CA1340862C (en) 1999-12-28
AU1939988A (en) 1988-12-21
FI895553A0 (fi) 1989-11-21
WO1988009384A1 (en) 1988-12-01
FI102191B (sv) 1998-10-30
DK260987D0 (da) 1987-05-22
IL86476A (en) 1994-01-25
NO301985B1 (no) 1998-01-05
JPH03501201A (ja) 1991-03-22
EP0362259A1 (en) 1990-04-11
ES2013337A6 (es) 1990-05-01
DE3855078T2 (de) 1996-07-18
DE3855078D1 (de) 1996-04-11
ATE135049T1 (de) 1996-03-15
NO890260D0 (no) 1989-01-20
NO890260L (no) 1989-01-20
JP3011274B2 (ja) 2000-02-21
EP0362259B1 (en) 1996-03-06
AU619750B2 (en) 1992-02-06
IL86476A0 (en) 1988-11-15

Similar Documents

Publication Publication Date Title
DE3888274D1 (de) Vorrichtung zur intensiven und kontrollierten Herstellung von Mikroorganismen durch Photosynthese.
FI102191B1 (sv) Förfarande för producering av 3-deshydroxicystatin C och en DNA-sekvens för användning vid förfarandet
DE69214438D1 (de) Mehrstufiger bestrahlungsprozess zur herstellung von zusammensetzungen auf acrylbasis, und derartig hergestellte zusammensetzungen
DE69022595D1 (de) Herstellung von kohlefaser-halbfabrikaten.
DE68919466D1 (de) Verfahren zur Herstellung von schraubenförmigen, glasfaserverstärkten Befestigungselementen.
DE3888642D1 (de) Rollflasche zur Züchtung von Zellengewebekulturen.
DE3885067D1 (de) Verfahren zur Herstellung von zusammengesetzten Membranen.
DE69224124D1 (de) Verfahren zur Herstellung von Dihomo-Gamma-Linolensäure und das in dieser enthaltende Lipid
DE3882242D1 (de) Fermentationsverfahren zur herstellung von 2-keto-l-gulonsaeuren.
GR3025718T3 (en) Progenitor b cell stimulating factor.
DE3883408D1 (de) Verfahren zur Herstellung von Avermectinen und die verwendeten Kulturen.
DE3886800D1 (de) Verfahren zur Herstellung von Kautschuklaminaten.
DE3885151D1 (de) Methode zur Herstellung von Methacrylatestern.
DE68908614D1 (de) Vorrichtung zur Herstellung von gebogenen Glasscheiben.
DE68909627D1 (de) Verfahren zur Herstellung von Aktivkohle.
DE69010171D1 (de) Mehrstufenverfahren zur Herstellung von Hexafluoropropylen.
DE59003144D1 (de) Destillationsanlage zur Herstellung von Wasserstoff-Peroxid.
DE3684434D1 (de) Verfahren zur herstellung von 2-keto-d-glukarsaeure.
ES2038974T3 (es) Metodo para incrementar selectivamente la proporcion de componentes principales individuales del complejo antibiotico a/16686.
DE68914236D1 (de) Verfahren zur Herstellung von Natriumhyaluronat durch Gärung.
DE3864512D1 (de) Verfahren zur herstellung von kandis mit gepressten gaszellen.
ATE155170T1 (de) Fermentationsprozess zur herstellung von pyrimidin
DE3850326D1 (de) Verfahren zur Herstellung von metallisierbaren Azofarbstoffen.
ATE81495T1 (de) Verfahren zur herstellung von natriumfluoralkoholaten.
DE3780665D1 (de) Mehrstufiges reduktionsverfahren zur herstellung von ferromagnetischem chromdioxid.

Legal Events

Date Code Title Description
FG Patent granted

Owner name: DAKO A/S

PC Transfer of assignment of patent

Owner name: DAKO DENMARK A/S

Free format text: DAKO DENMARK A/S

MA Patent expired