ES8900049A1 - Un procedimiento para preparar nuevas imidazo(1,2-a)pirimidinas' - Google Patents

Un procedimiento para preparar nuevas imidazo(1,2-a)pirimidinas'

Info

Publication number
ES8900049A1
ES8900049A1 ES557324A ES557324A ES8900049A1 ES 8900049 A1 ES8900049 A1 ES 8900049A1 ES 557324 A ES557324 A ES 557324A ES 557324 A ES557324 A ES 557324A ES 8900049 A1 ES8900049 A1 ES 8900049A1
Authority
ES
Spain
Prior art keywords
carbon atoms
alkyl
group
oxadiazol
alkenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES557324A
Other languages
English (en)
Other versions
ES557324A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES557324A0 publication Critical patent/ES557324A0/es
Publication of ES8900049A1 publication Critical patent/ES8900049A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

SE HACE REACCIONAR UN COMPUESTO DE FORMULA GENERAL (I) CON HIDRATO DE HIDRAZINA POR CALENTAMIENTO DE LA MEZCLA DE REACCION EN UN DISOLVENTE ORGANICO A REFLUJO, PARA OBTENER UN COMPUESTO DE FORMULA GENERAL (II) QUE SE HACE REACCIONAR BIEN CON UN ANHIDRO O UN CLORURO DE UN ACIDO OBTENIENDOSE COMO PRODUCTO UN COMPUESTO DE FORMULA GENERAL (III), BIEN CON UN ORTOESTER OBTENIENDOSE UN COMPUESTO DE FORMULA GENERAL (IV). AMBOS COMPUESTOS (III) Y (IV) SE CICLAN TERMICAMENTE PARA OBTENER EL COMPUESTO FINAL DE FORMULA GENERAL (V). LAS COMPOSICIONES FARMACEUTICAS DE ESTE COMPUESTO SE UTILIZAN PARA EL TRATAMIENTO DE LA ANSIEDAD, IRRITABILIDAD, DEPRESION. *FORMULA*
ES557324A 1984-12-19 1987-01-16 Un procedimiento para preparar nuevas imidazo(1,2-a)pirimidinas' Expired ES8900049A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848432073A GB8432073D0 (en) 1984-12-19 1984-12-19 Chemical compounds

Publications (2)

Publication Number Publication Date
ES557324A0 ES557324A0 (es) 1988-11-16
ES8900049A1 true ES8900049A1 (es) 1988-11-16

Family

ID=10571440

Family Applications (2)

Application Number Title Priority Date Filing Date
ES550100A Expired ES8705432A1 (es) 1984-12-19 1985-12-18 Un procedimiento para preparar nuevas imidazo(1,2-a)pirimi- dinas
ES557324A Expired ES8900049A1 (es) 1984-12-19 1987-01-16 Un procedimiento para preparar nuevas imidazo(1,2-a)pirimidinas'

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES550100A Expired ES8705432A1 (es) 1984-12-19 1985-12-18 Un procedimiento para preparar nuevas imidazo(1,2-a)pirimi- dinas

Country Status (16)

Country Link
US (1) US4703049A (es)
EP (1) EP0197230B1 (es)
JP (1) JPS61180786A (es)
AT (1) ATE49971T1 (es)
AU (1) AU581713B2 (es)
CA (1) CA1248528A (es)
DE (1) DE3575726D1 (es)
DK (1) DK588785A (es)
ES (2) ES8705432A1 (es)
FI (1) FI82247C (es)
GB (2) GB8432073D0 (es)
GR (1) GR853021B (es)
HU (1) HU193843B (es)
PT (1) PT81693B (es)
SU (1) SU1650013A3 (es)
ZA (1) ZA859650B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8613591D0 (en) * 1986-06-04 1986-07-09 Roussel Lab Ltd Chemical compounds
DK522187D0 (da) * 1987-10-06 1987-10-06 Ferrosan As Imidozothienopyrimidiner, deres fremstilling og anvendelse
GB8905130D0 (en) * 1989-03-07 1989-04-19 Pfizer Ltd Therapeutic agents
US5185446A (en) * 1990-09-04 1993-02-09 Neurogen Corporation Certain cycloalkyl imidazopyrimidines; a new class of gaba brainreceptor ligands
US5646152A (en) * 1994-06-15 1997-07-08 Pfizer Inc. Methods of administering CRF antagonists
EP3752492B1 (en) * 2018-02-12 2022-12-21 Bayer Aktiengesellschaft Fungicidal oxadiazoles

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
IL69417A (en) * 1982-08-27 1987-12-20 Roussel Uclaf 2-acyl imidazo(1,2-a)pyrimidines,their preparation and pharmaceutical compositions containing them
GB8305245D0 (en) * 1983-02-25 1983-03-30 Fujisawa Pharmaceutical Co Imidazo-heterocyclic compounds

Also Published As

Publication number Publication date
PT81693A (en) 1986-01-01
DK588785A (da) 1986-06-20
ES8705432A1 (es) 1987-05-01
EP0197230A1 (fr) 1986-10-15
HU193843B (en) 1987-12-28
ATE49971T1 (de) 1990-02-15
ES557324A0 (es) 1988-11-16
HUT40437A (en) 1986-12-28
DE3575726D1 (de) 1990-03-08
FI82247C (fi) 1991-02-11
GB8432073D0 (en) 1985-01-30
GR853021B (es) 1986-04-15
FI855060A0 (fi) 1985-12-18
SU1650013A3 (ru) 1991-05-15
GB2170199A (en) 1986-07-30
CA1248528A (en) 1989-01-10
EP0197230B1 (fr) 1990-01-31
ES550100A0 (es) 1987-05-01
GB2170199B (en) 1988-03-16
FI82247B (fi) 1990-10-31
PT81693B (pt) 1988-02-17
FI855060A (fi) 1986-06-20
DK588785D0 (da) 1985-12-18
JPS61180786A (ja) 1986-08-13
GB8531161D0 (en) 1986-01-29
ZA859650B (en) 1987-02-25
AU5148785A (en) 1986-06-26
US4703049A (en) 1987-10-27
AU581713B2 (en) 1989-03-02

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506