ES8802231A1 - Un procedimiento para extraer la sustancia quimica activa de la planta del aloe a partir de sus hojas - Google Patents
Un procedimiento para extraer la sustancia quimica activa de la planta del aloe a partir de sus hojasInfo
- Publication number
- ES8802231A1 ES8802231A1 ES557820A ES557820A ES8802231A1 ES 8802231 A1 ES8802231 A1 ES 8802231A1 ES 557820 A ES557820 A ES 557820A ES 557820 A ES557820 A ES 557820A ES 8802231 A1 ES8802231 A1 ES 8802231A1
- Authority
- ES
- Spain
- Prior art keywords
- aloe
- products
- juice
- compositions
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/244—Anthraquinone radicals, e.g. sennosides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Abstract
UNA SUSTANCIA QUIMICA (I) CON MONOMEROS DE MANOSA Y ENLACES BETA (194), PRESENTE EN EL ALOE, SE PREPARA A PARTIR DE ESTA PLANTA, MEDIANTE: A) EL LAVADO DE SUS HOJAS CON UNA SOLUCION BACTERICIDA, Y OPCIONALMENTE LA SEPARACION UNA PRIMERA PORCION EXTREMA DE LA HOJA Y DRENADO, PRESERVADO Y RECOLECCION DE LA SAVIA RICA EN ANTRAQUINONA; B) LA SEPARACION DE LA CORTEZA DE LA HOJA PARA PRODUCIR UNA TIRA DE GEL; C) LA TRITURACION Y MOLIENDA DE LA HOJA CON POSTERIOR DIALIZADO PARA OBTENER EL GEL; D) MOLIENDA DEL GEL PARA OBTENER UN JUGO HOMOGENEO; E) PRECIPITACION DENTRO DEL JUGO OBTENIDO DE LA SUSTANCIA ACTIVA POR ADICION DE 4 PARTES DE ETANOL; F) SECADO POR LIOFILIZACION E IRRADIACION CON RAYOS GAMMA O MICROONDAS PARA OBTENER UNA SUSTANCIA ESTABLE Y LIOFILIZADA. LAS VARIEDADES DE ALOE UTILIZADAS SON EL ALOE FEROX, ALOE AFRICANA, AFRICANA FEROX, ALOE DICHOTOMA Y ALOE VERA, ESTA ULTIMA SE SOMETE OPCIONALMENTE ENTRE OTRAS TRANSFORMACIONES A: OXIDACION CON PEROXIDO DE HIDROGENO, ESCISION DE PERYODATO YMETILACION CON SULFATO DE DIMETILO. LA GELATINA DE ALOE EXENTA SE ANTRAQUINASAS ES APLICABLE EN EL TRATAMIENTO DE LAS HERIDAS DE LA PIEL.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75032185A | 1985-06-28 | 1985-06-28 | |
US75485985A | 1985-07-12 | 1985-07-12 | |
US81002585A | 1985-12-17 | 1985-12-17 | |
US06/869,261 US4735935A (en) | 1985-12-17 | 1986-06-05 | Process for preparation of aloe products products, produced thereby and compositions thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8802231A1 true ES8802231A1 (es) | 1988-04-16 |
ES557820A0 ES557820A0 (es) | 1988-04-16 |
Family
ID=27505653
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES556686A Expired ES8801986A1 (es) | 1985-06-28 | 1986-06-25 | Un procedimiento para producir un gel o jugo de aloe sustancialmente exento de antraquinona. |
ES557759A Expired ES8802390A1 (es) | 1985-06-28 | 1987-09-30 | Un procedimiento para extraer la substancia quimica activa de la planta del aloe a partir de hojas de esta planta |
ES557821A Expired ES8802232A1 (es) | 1985-06-28 | 1988-02-15 | Un procedimiento para extraer la sustancia quimica activa de la planta del aloe a partir de sus hojas |
ES557820A Expired ES8802231A1 (es) | 1985-06-28 | 1988-02-15 | Un procedimiento para extraer la sustancia quimica activa de la planta del aloe a partir de sus hojas |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES556686A Expired ES8801986A1 (es) | 1985-06-28 | 1986-06-25 | Un procedimiento para producir un gel o jugo de aloe sustancialmente exento de antraquinona. |
ES557759A Expired ES8802390A1 (es) | 1985-06-28 | 1987-09-30 | Un procedimiento para extraer la substancia quimica activa de la planta del aloe a partir de hojas de esta planta |
ES557821A Expired ES8802232A1 (es) | 1985-06-28 | 1988-02-15 | Un procedimiento para extraer la sustancia quimica activa de la planta del aloe a partir de sus hojas |
Country Status (13)
Country | Link |
---|---|
EP (2) | EP0227806B1 (es) |
CN (1) | CN86104468A (es) |
AU (1) | AU607681B2 (es) |
CA (1) | CA1305475C (es) |
DE (2) | DE3665262D1 (es) |
ES (4) | ES8801986A1 (es) |
IE (1) | IE65367B1 (es) |
IL (1) | IL79225A0 (es) |
MX (1) | MX164570B (es) |
NZ (1) | NZ216663A (es) |
OA (1) | OA08487A (es) |
PT (1) | PT82862B (es) |
WO (1) | WO1987000052A1 (es) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5106616A (en) * | 1988-01-14 | 1992-04-21 | Carrington Laboratories, Inc. | Administration of acemannan |
US4851224A (en) * | 1986-06-05 | 1989-07-25 | Carrington Laboratories, Inc. | Process for preparation of aloe products |
WO1993008810A1 (en) * | 1991-11-05 | 1993-05-13 | Carrington Laboratories, Inc. | Uses of aloe products, e.g. acemannan, in the treatment of diseases requiring intervention of the immune system for cure |
US5409703A (en) * | 1993-06-24 | 1995-04-25 | Carrington Laboratories, Inc. | Dried hydrogel from hydrophilic-hygroscopic polymer |
US5902796A (en) * | 1995-09-22 | 1999-05-11 | Carrington Laboratories, Inc. | Bioactive factors of aloe vera plants |
ATE224211T1 (de) | 1996-07-10 | 2002-10-15 | Coloplast As | Klebstoffezubereitung und deren verwendung |
US6929807B1 (en) | 1996-08-09 | 2005-08-16 | Mannatech, Inc. | Compositions of plant carbohydrates as dietary supplements |
CN1063037C (zh) * | 1998-02-11 | 2001-03-14 | 昆明大一实业总公司 | 果肉型芦荟饮料及其制备方法 |
CN1235727C (zh) * | 1999-01-13 | 2006-01-11 | 宋维宁 | 一种复合材料产品 |
US6506387B1 (en) | 1999-04-28 | 2003-01-14 | Paxa N.V. | Method for preparing aloin by extraction |
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
DE102004032051A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
SA07280459B1 (ar) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
WO2008059074A1 (es) * | 2006-11-11 | 2008-05-22 | Luciano Reverón E Hijos S. L. | Estabilización del extracto de aloe vera |
DE102007011485A1 (de) | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
US10543247B2 (en) | 2007-05-11 | 2020-01-28 | Woodcliff Skincare Solutions, Inc. | Aloe preparation for skin enhancement |
BRPI0906467C1 (pt) | 2008-01-25 | 2021-05-25 | Gruenenthal Gmbh | forma de dosagem farmacêutica com formato exterior modificado resistente à ruptura e com liberação controlada |
LT2273983T (lt) | 2008-05-09 | 2016-10-25 | Grünenthal GmbH | Tarpinės miltelių kompozicijos gamybos būdas ir galutinė kieta dozavimo forma naudojant purškalo kietinimo stadija |
EP2456427B1 (en) | 2009-07-22 | 2015-03-04 | Grünenthal GmbH | Hot-melt extruded controlled release dosage form |
AU2010275754B2 (en) | 2009-07-22 | 2014-05-15 | Grünenthal GmbH | Tamper-resistant dosage form for oxidation-sensitive opioids |
CA2714093C (en) | 2009-09-01 | 2014-04-29 | Eau Matelo Inc. | Process to extract drinking water from plant, plant drinking water and beverages thereof |
WO2012028319A1 (en) | 2010-09-02 | 2012-03-08 | Grünenthal GmbH | Tamper resistant dosage form comprising inorganic salt |
MX2013002293A (es) | 2010-09-02 | 2013-05-09 | Gruenenthal Gmbh | Forma de dosificacion resistente a alteracion que comprende un polimero anionico. |
BR112014002022A2 (pt) | 2011-07-29 | 2017-02-21 | Gruenenthal Gmbh | comprimido resistente à violação proporcionando liberação de fármaco imediata |
LT2736497T (lt) | 2011-07-29 | 2017-11-10 | Grünenthal GmbH | Sugadinimui atspari tabletė, pasižyminti greitu vaisto atpalaidavimu |
US20130225697A1 (en) | 2012-02-28 | 2013-08-29 | Grunenthal Gmbh | Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer |
AU2013248351B2 (en) | 2012-04-18 | 2018-04-26 | Grunenthal Gmbh | Tamper resistant and dose-dumping resistant pharmaceutical dosage form |
US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
CA2907950A1 (en) | 2013-05-29 | 2014-12-04 | Grunenthal Gmbh | Tamper-resistant dosage form containing one or more particles |
JP6466417B2 (ja) | 2013-05-29 | 2019-02-06 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 二峰性放出プロファイルを有する改変防止(tamper−resistant)剤形 |
EA032465B1 (ru) | 2013-07-12 | 2019-05-31 | Грюненталь Гмбх | Защищенная от применения не по назначению пероральная фармацевтическая лекарственная форма, содержащая этиленвинилацетатный полимер, и способ ее изготовления |
WO2015013420A1 (en) * | 2013-07-25 | 2015-01-29 | Geophia Llc | Utilization of tropical plant juice byproduct through separation of naturally occuring minerals |
AU2014356581C1 (en) | 2013-11-26 | 2020-05-28 | Grunenthal Gmbh | Preparation of a powdery pharmaceutical composition by means of cryo-milling |
ES2542156B1 (es) * | 2014-01-30 | 2016-05-13 | Maria Del Mar TELLO DE JUAN | Gel frío de Aloe Vera natural sin estabilizadores |
CN106572980A (zh) | 2014-05-12 | 2017-04-19 | 格吕伦塔尔有限公司 | 包含他喷他多的防篡改即释胶囊制剂 |
CN106456550A (zh) | 2014-05-26 | 2017-02-22 | 格吕伦塔尔有限公司 | 避免乙醇剂量倾泻的多颗粒 |
CN107072214A (zh) * | 2014-09-23 | 2017-08-18 | 安约恩生物制品公司 | 基于矿物质的组合物及其用途 |
AU2016251854A1 (en) | 2015-04-24 | 2017-10-19 | Grunenthal Gmbh | Tamper-resistant dosage form with immediate release and resistance against solvent extraction |
MX2018001594A (es) | 2015-08-10 | 2018-09-26 | Beem Biologics Inc | Composiciones y su uso para control de plagas y para inducir una hormona vegetal y la regulacion genica para produccion y defensa mejoradas de las plantas. |
JP2018526414A (ja) | 2015-09-10 | 2018-09-13 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 乱用抑止性の即放性製剤を用いた経口過剰摂取に対する保護 |
US10322156B2 (en) * | 2016-07-07 | 2019-06-18 | Herbalife International Of America, Inc. | Methods of treatment using purified (decolorized) aloe vera leaf dry juice |
CN107279999A (zh) * | 2017-07-21 | 2017-10-24 | 广东原绿生物工程有限公司 | 一种芦荟凝胶的丁、汁混合产品的制备方法 |
CN110389057A (zh) * | 2018-04-23 | 2019-10-29 | 上海伯顿医疗设备有限公司 | 一体化多功能生物样品处理器 |
WO2022051419A1 (en) * | 2020-09-02 | 2022-03-10 | Herbalife International Of America, Inc. | Compositions and methods for treating metabolic disruption |
CN112892047B (zh) * | 2021-01-14 | 2022-05-27 | 珠海积家世纪日化有限公司 | 一种化妆品添加物芦荟精华液制备工艺 |
CN113693995A (zh) * | 2021-06-18 | 2021-11-26 | 海南九面通科技有限公司 | 一种芦荟皮肤营养液的制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US360511A (en) * | 1887-04-05 | Automatic weighing and package-filling machine | ||
FR3068M (fr) * | 1956-12-20 | 1965-01-18 | Alexander Farkas | Médicament topique applicable notamment au traitement des blessures ouvertes et des brulures. |
US3360511A (en) * | 1966-11-22 | 1967-12-26 | Farkas Alexander | Aloe polysaccharide composition and its preparation |
US3892853A (en) * | 1967-05-22 | 1975-07-01 | Aloe 99 & 0 Inc | Stabilized aloe vera gel and preparation of same |
US3920816A (en) * | 1967-12-29 | 1975-11-18 | Vis Mediatrix Naturae Scient L | Composition for treating respiratory diseases |
US4178372A (en) * | 1978-03-06 | 1979-12-11 | Coats Billy C | Hypoallergenic stabilized aloe vera gel |
US4446131A (en) * | 1982-06-09 | 1984-05-01 | Aloe Vera Of America, Inc. | Controlled temperature process for manufacturing of improved stabilized aloe vera |
US4465629A (en) * | 1983-03-17 | 1984-08-14 | Maughan Rex G | Method to increase color fastness of stabilized aloe vera |
US4555987A (en) * | 1983-07-22 | 1985-12-03 | Tumlinson Larry N | Method and apparatus for extraction of aloe vera gel |
-
1986
- 1986-06-20 DE DE8686904550T patent/DE3665262D1/de not_active Expired
- 1986-06-20 AU AU61255/86A patent/AU607681B2/en not_active Expired
- 1986-06-20 WO PCT/US1986/001335 patent/WO1987000052A1/en active IP Right Grant
- 1986-06-20 EP EP86904550A patent/EP0227806B1/en not_active Expired
- 1986-06-20 DE DE88121318T patent/DE3689195T2/de not_active Expired - Lifetime
- 1986-06-20 EP EP88121318A patent/EP0328775B1/en not_active Expired - Lifetime
- 1986-06-24 IL IL79225A patent/IL79225A0/xx unknown
- 1986-06-24 IE IE168586A patent/IE65367B1/en unknown
- 1986-06-25 NZ NZ216663A patent/NZ216663A/xx unknown
- 1986-06-25 ES ES556686A patent/ES8801986A1/es not_active Expired
- 1986-06-26 CN CN8686104468A patent/CN86104468A/zh active Pending
- 1986-06-27 MX MX2952A patent/MX164570B/es unknown
- 1986-06-27 CA CA000512680A patent/CA1305475C/en not_active Expired - Lifetime
- 1986-06-27 PT PT82862A patent/PT82862B/pt unknown
-
1987
- 1987-02-26 OA OA59078A patent/OA08487A/xx unknown
- 1987-09-30 ES ES557759A patent/ES8802390A1/es not_active Expired
-
1988
- 1988-02-15 ES ES557821A patent/ES8802232A1/es not_active Expired
- 1988-02-15 ES ES557820A patent/ES8802231A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
MX164570B (es) | 1992-09-02 |
EP0227806A1 (en) | 1987-07-08 |
OA08487A (fr) | 1988-07-29 |
EP0227806B1 (en) | 1989-08-30 |
IE861685L (en) | 1987-06-17 |
NZ216663A (en) | 1988-08-30 |
EP0328775B1 (en) | 1993-10-20 |
EP0227806A4 (en) | 1987-10-19 |
IL79225A0 (en) | 1986-09-30 |
EP0328775A1 (en) | 1989-08-23 |
DE3689195D1 (de) | 1993-11-25 |
ES556686A0 (es) | 1988-03-16 |
AU6125586A (en) | 1987-01-30 |
ES557759A0 (es) | 1988-05-16 |
CN86104468A (zh) | 1986-12-31 |
IE65367B1 (en) | 1995-10-18 |
PT82862A (en) | 1986-07-01 |
ES557820A0 (es) | 1988-04-16 |
WO1987000052A1 (en) | 1987-01-15 |
CA1305475C (en) | 1992-07-21 |
AU607681B2 (en) | 1991-03-14 |
ES8801986A1 (es) | 1988-03-16 |
ES557821A0 (es) | 1988-04-16 |
ES8802390A1 (es) | 1988-05-16 |
DE3665262D1 (en) | 1989-10-05 |
PT82862B (pt) | 1989-01-17 |
ES8802232A1 (es) | 1988-04-16 |
DE3689195T2 (de) | 1994-05-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20080308 |