ES8802137A1 - Cyclopentyl ethes and their preparation and pharmaceutical formulation - Google Patents

Cyclopentyl ethes and their preparation and pharmaceutical formulation

Info

Publication number
ES8802137A1
ES8802137A1 ES554238A ES554238A ES8802137A1 ES 8802137 A1 ES8802137 A1 ES 8802137A1 ES 554238 A ES554238 A ES 554238A ES 554238 A ES554238 A ES 554238A ES 8802137 A1 ES8802137 A1 ES 8802137A1
Authority
ES
Spain
Prior art keywords
ethes
cyclopentyl
preparation
pharmaceutical formulation
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES554238A
Other languages
Spanish (es)
Other versions
ES554238A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES554238A0 publication Critical patent/ES554238A0/en
Publication of ES8802137A1 publication Critical patent/ES8802137A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Abstract

Compounds are described of formula (I> < IMAGE > in which n is 1 or 2 m is 2-5 and x is -CH=CH- or -CH2-CH2- or m is 1-4 and x is -CH=C=CH- R<1> is phenyl, substituted phenyl or naphthyl Y substituted or unsubstituted 3-phenoxy-2-hydroxypropyl. These compounds inhibit gastric acid secretion and provide gastrointestinal cytoprotection, and may be formulated for use in the treatment of ulcers.
ES554238A 1985-04-23 1986-04-22 Cyclopentyl ethes and their preparation and pharmaceutical formulation Expired ES8802137A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858510277A GB8510277D0 (en) 1985-04-23 1985-04-23 Carbocyclic compounds

Publications (2)

Publication Number Publication Date
ES554238A0 ES554238A0 (en) 1988-04-01
ES8802137A1 true ES8802137A1 (en) 1988-04-01

Family

ID=10578043

Family Applications (3)

Application Number Title Priority Date Filing Date
ES554238A Expired ES8802137A1 (en) 1985-04-23 1986-04-22 Cyclopentyl ethes and their preparation and pharmaceutical formulation
ES557659A Expired ES8900044A1 (en) 1985-04-23 1987-08-12 Cyclopentyl ethes and their preparation and pharmaceutical formulation
ES557828A Expired - Fee Related ES9000022A1 (en) 1985-04-23 1988-04-12 Cyclopentyl ethes and their preparation and pharmaceutical formulation

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES557659A Expired ES8900044A1 (en) 1985-04-23 1987-08-12 Cyclopentyl ethes and their preparation and pharmaceutical formulation
ES557828A Expired - Fee Related ES9000022A1 (en) 1985-04-23 1988-04-12 Cyclopentyl ethes and their preparation and pharmaceutical formulation

Country Status (29)

Country Link
JP (1) JPS61249951A (en)
KR (1) KR860008132A (en)
CN (1) CN1011783B (en)
AT (1) AT395421B (en)
AU (1) AU593797B2 (en)
BE (1) BE904656A (en)
CA (1) CA1275094A (en)
CH (1) CH667265A5 (en)
DE (1) DE3613573A1 (en)
DK (1) DK183986A (en)
ES (3) ES8802137A1 (en)
FI (1) FI85368C (en)
FR (1) FR2580632B1 (en)
GB (2) GB8510277D0 (en)
GR (1) GR861060B (en)
HK (1) HK51691A (en)
HU (1) HU199411B (en)
IL (1) IL78552A (en)
IT (1) IT1190277B (en)
LU (1) LU86404A1 (en)
MY (1) MY100829A (en)
NL (1) NL8601025A (en)
NO (1) NO165069C (en)
NZ (1) NZ215910A (en)
PH (1) PH23597A (en)
PT (1) PT82440B (en)
SE (1) SE460193B (en)
SG (1) SG92990G (en)
ZA (1) ZA863006B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8625325D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Chemical compounds
GB8625322D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Chemical compounds
GB8625326D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Medicaments
GB8625321D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Chemical compounds
EP0265247B1 (en) * 1986-10-22 1990-08-08 Glaxo Group Limited Cyclopentyl ethers and their preparation and pharmaceutical formulation
JP2696933B2 (en) * 1987-06-16 1998-01-14 日産化学工業株式会社 Substituted cyclic ketones and substituted cyclic enones and methods for their preparation
US5231208A (en) * 1987-06-16 1993-07-27 Nissan Chemical Industries, Ltd. Substituted cyclic ketones, substituted cyclic enones, and process for producing the same
US5254708A (en) * 1987-06-16 1993-10-19 Nissan Chemical Industries, Ltd. Substituted cyclic ketones, substituted cyclic enones, and process for producing the same
US5227505A (en) * 1987-06-16 1993-07-13 Nissan Chemical Industries, Ltd. Substituted cyclic ketones, substituted cyclic enones, and process for producing the same
GB8822141D0 (en) * 1988-09-21 1988-10-26 Glaxo Group Ltd Chemical compounds
WO1999032441A1 (en) * 1997-12-22 1999-07-01 Alcon Laboratories, Inc. 13-oxa prostaglandins for the treatment of glaucoma and ocular hypertension
WO2005009468A1 (en) 2003-07-25 2005-02-03 Ono Pharmaceutical Co., Ltd. Remedy for cartilage-related diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ197729A (en) * 1980-08-12 1985-03-20 Sanofi Sa 13-oxaprostanoic acid derivatives and pharmaceutical compositions
GB2082176B (en) * 1980-08-12 1984-07-11 Sanofi Sa Heteroprostaglandin derivatives and processes for preparing them
GB8410396D0 (en) * 1984-04-24 1984-05-31 Glaxo Group Ltd Carbocyclic compounds

Also Published As

Publication number Publication date
AU593797B2 (en) 1990-02-22
PH23597A (en) 1989-09-11
HK51691A (en) 1991-07-12
FR2580632A1 (en) 1986-10-24
PT82440B (en) 1988-03-03
ES8900044A1 (en) 1988-11-16
SE8601852L (en) 1986-10-24
IL78552A0 (en) 1986-08-31
ATA106986A (en) 1992-05-15
CA1275094A (en) 1990-10-09
FI85368B (en) 1991-12-31
FI85368C (en) 1992-04-10
BE904656A (en) 1986-10-22
GB8609821D0 (en) 1986-05-29
GB8510277D0 (en) 1985-05-30
JPS61249951A (en) 1986-11-07
GB2174702B (en) 1988-06-15
MY100829A (en) 1991-03-15
DE3613573A1 (en) 1986-10-30
NO861584L (en) 1986-10-24
IT1190277B (en) 1988-02-16
GB2174702A (en) 1986-11-12
NO165069C (en) 1990-12-19
CH667265A5 (en) 1988-09-30
FI861687A (en) 1986-10-24
HUT45010A (en) 1988-05-30
DK183986D0 (en) 1986-04-22
CN1011783B (en) 1991-02-27
AU5646186A (en) 1986-10-30
CN86102778A (en) 1986-10-22
ES554238A0 (en) 1988-04-01
NL8601025A (en) 1986-11-17
LU86404A1 (en) 1986-11-05
PT82440A (en) 1986-05-01
KR860008132A (en) 1986-11-12
ES557659A0 (en) 1988-11-16
SE8601852D0 (en) 1986-04-22
HU199411B (en) 1990-02-28
IT8647919A0 (en) 1986-04-22
NO165069B (en) 1990-09-10
ES9000022A1 (en) 1990-02-16
DK183986A (en) 1986-10-24
FR2580632B1 (en) 1989-09-15
IL78552A (en) 1989-12-15
GR861060B (en) 1986-08-25
ES557828A0 (en) 1990-02-16
AT395421B (en) 1992-12-28
FI861687A0 (en) 1986-04-22
NZ215910A (en) 1989-08-29
ZA863006B (en) 1986-12-30
SE460193B (en) 1989-09-18
SG92990G (en) 1991-01-18

Similar Documents

Publication Publication Date Title
ES8102125A1 (en) intermediates and their preparation.
ES8802137A1 (en) Cyclopentyl ethes and their preparation and pharmaceutical formulation
NO159291C (en) PROCEDURE FOR THE PREPARATION OF GAMMA-SUBSTITUTED 3 (R) HYDROXYLIC ACID DERIVATIVES.
DE3567453D1 (en) Cyclopentyl ethers and their preparation and pharmaceutical formulation
ES8401944A1 (en) Salicylic-acid derivatives, process for their preparation, pharmaceutical preparations based on these compounds and their use.
DE3477488D1 (en) Polymethoxybenzyl piperazine derivatives, processes for their preparation and pharmaceutical compositions containing said derivatives
EP0331092A3 (en) Alpha-amino-carboxylic-acid derivatives, their preparation and use
AU578295B2 (en) Phenyl-substituted naphthyridines and their use as anti-ulcer drugs
DE3882381D1 (en)
AU579295B2 (en) New thiazole derivatives, a process for the preparation thereof and pharmaceutical compositions containing them
ES467886A1 (en) 3 beta -Hydroxy-18 beta -olean-9-en-30-oic acids
AU548410B2 (en) 5-6-dihydro-11-alkylene-morphanthridin-6-one
ES8703847A1 (en) Sulfonyl-guanidinopyrimidine derivatives.
ES8703855A1 (en) Sulfonyl-guanidinotriazine derivatives.
IE830147L (en) Hydroxyalkane diphosphonic acid derivatives
EP0265248A3 (en) Cyclopentyl ethers and their preparation and pharmaceutical formulation
JPS53130648A (en) Anthraquinone-1-carboxylic acid amide-n-halide and its preparation

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401