BE904656A - CYCLOPENTYL ETHERS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM. - Google Patents

CYCLOPENTYL ETHERS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM.

Info

Publication number
BE904656A
BE904656A BE0/216578A BE216578A BE904656A BE 904656 A BE904656 A BE 904656A BE 0/216578 A BE0/216578 A BE 0/216578A BE 216578 A BE216578 A BE 216578A BE 904656 A BE904656 A BE 904656A
Authority
BE
Belgium
Prior art keywords
preparation
pharmaceutical formulations
formulations containing
cyclopentyl ethers
cyclopentyl
Prior art date
Application number
BE0/216578A
Other languages
French (fr)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of BE904656A publication Critical patent/BE904656A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Ethers cyclopentyliques, répondant à la formule ci-dessous dans laquelle n est 1 ou 2, m est 2-5 et X est -CH=CH-ou -CH2-CH2; ou m est 1-4 et X est -CH=C=CH-; R1 représente un groupe phényle, phényle substitué ou naphtyle, Y représente un radical 3-phénoxy-2-hydroxypropyle substitué ou non. Ces composés inhibent la sécrétion d'acide gastrique et assurent une cytoprotetion gastro-intestinale et s'utilisent pour le triatement des ulcères.Cyclopentyl ethers, corresponding to the formula below in which n is 1 or 2, m is 2-5 and X is -CH = CH-or -CH2-CH2; or m is 1-4 and X is -CH = C = CH-; R1 represents a phenyl, substituted phenyl or naphthyl group, Y represents a substituted or unsubstituted 3-phenoxy-2-hydroxypropyl radical. These compounds inhibit the secretion of gastric acid and ensure gastrointestinal cytoprotection and are used for the triation of ulcers.

BE0/216578A 1985-04-23 1986-04-22 CYCLOPENTYL ETHERS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM. BE904656A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858510277A GB8510277D0 (en) 1985-04-23 1985-04-23 Carbocyclic compounds

Publications (1)

Publication Number Publication Date
BE904656A true BE904656A (en) 1986-10-22

Family

ID=10578043

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/216578A BE904656A (en) 1985-04-23 1986-04-22 CYCLOPENTYL ETHERS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM.

Country Status (29)

Country Link
JP (1) JPS61249951A (en)
KR (1) KR860008132A (en)
CN (1) CN1011783B (en)
AT (1) AT395421B (en)
AU (1) AU593797B2 (en)
BE (1) BE904656A (en)
CA (1) CA1275094A (en)
CH (1) CH667265A5 (en)
DE (1) DE3613573A1 (en)
DK (1) DK183986A (en)
ES (3) ES8802137A1 (en)
FI (1) FI85368C (en)
FR (1) FR2580632B1 (en)
GB (2) GB8510277D0 (en)
GR (1) GR861060B (en)
HK (1) HK51691A (en)
HU (1) HU199411B (en)
IL (1) IL78552A (en)
IT (1) IT1190277B (en)
LU (1) LU86404A1 (en)
MY (1) MY100829A (en)
NL (1) NL8601025A (en)
NO (1) NO165069C (en)
NZ (1) NZ215910A (en)
PH (1) PH23597A (en)
PT (1) PT82440B (en)
SE (1) SE460193B (en)
SG (1) SG92990G (en)
ZA (1) ZA863006B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8625321D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Chemical compounds
EP0265247B1 (en) * 1986-10-22 1990-08-08 Glaxo Group Limited Cyclopentyl ethers and their preparation and pharmaceutical formulation
GB8625325D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Chemical compounds
GB8625322D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Chemical compounds
GB8625326D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Medicaments
JP2696933B2 (en) * 1987-06-16 1998-01-14 日産化学工業株式会社 Substituted cyclic ketones and substituted cyclic enones and methods for their preparation
US5227505A (en) * 1987-06-16 1993-07-13 Nissan Chemical Industries, Ltd. Substituted cyclic ketones, substituted cyclic enones, and process for producing the same
US5231208A (en) * 1987-06-16 1993-07-27 Nissan Chemical Industries, Ltd. Substituted cyclic ketones, substituted cyclic enones, and process for producing the same
US5254708A (en) * 1987-06-16 1993-10-19 Nissan Chemical Industries, Ltd. Substituted cyclic ketones, substituted cyclic enones, and process for producing the same
GB8822141D0 (en) * 1988-09-21 1988-10-26 Glaxo Group Ltd Chemical compounds
WO1999032441A1 (en) * 1997-12-22 1999-07-01 Alcon Laboratories, Inc. 13-oxa prostaglandins for the treatment of glaucoma and ocular hypertension
EP2422814A1 (en) 2003-07-25 2012-02-29 Ono Pharmaceutical Co., Ltd. Remedy for cartilage-related diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2082176B (en) * 1980-08-12 1984-07-11 Sanofi Sa Heteroprostaglandin derivatives and processes for preparing them
NZ197729A (en) * 1980-08-12 1985-03-20 Sanofi Sa 13-oxaprostanoic acid derivatives and pharmaceutical compositions
GB8410396D0 (en) * 1984-04-24 1984-05-31 Glaxo Group Ltd Carbocyclic compounds

Also Published As

Publication number Publication date
GB8510277D0 (en) 1985-05-30
GR861060B (en) 1986-08-25
KR860008132A (en) 1986-11-12
NL8601025A (en) 1986-11-17
PT82440A (en) 1986-05-01
HK51691A (en) 1991-07-12
ATA106986A (en) 1992-05-15
ES554238A0 (en) 1988-04-01
FI85368B (en) 1991-12-31
ZA863006B (en) 1986-12-30
ES9000022A1 (en) 1990-02-16
FR2580632A1 (en) 1986-10-24
PH23597A (en) 1989-09-11
DK183986A (en) 1986-10-24
IT8647919A0 (en) 1986-04-22
MY100829A (en) 1991-03-15
NO165069C (en) 1990-12-19
FR2580632B1 (en) 1989-09-15
ES557828A0 (en) 1990-02-16
ES557659A0 (en) 1988-11-16
IT1190277B (en) 1988-02-16
FI861687A0 (en) 1986-04-22
NO165069B (en) 1990-09-10
CH667265A5 (en) 1988-09-30
HU199411B (en) 1990-02-28
FI861687A (en) 1986-10-24
AU5646186A (en) 1986-10-30
CN86102778A (en) 1986-10-22
SE460193B (en) 1989-09-18
IL78552A0 (en) 1986-08-31
SE8601852D0 (en) 1986-04-22
AU593797B2 (en) 1990-02-22
CA1275094A (en) 1990-10-09
GB8609821D0 (en) 1986-05-29
NZ215910A (en) 1989-08-29
NO861584L (en) 1986-10-24
PT82440B (en) 1988-03-03
GB2174702A (en) 1986-11-12
DK183986D0 (en) 1986-04-22
ES8900044A1 (en) 1988-11-16
JPS61249951A (en) 1986-11-07
HUT45010A (en) 1988-05-30
IL78552A (en) 1989-12-15
FI85368C (en) 1992-04-10
DE3613573A1 (en) 1986-10-30
AT395421B (en) 1992-12-28
LU86404A1 (en) 1986-11-05
ES8802137A1 (en) 1988-04-01
SG92990G (en) 1991-01-18
GB2174702B (en) 1988-06-15
CN1011783B (en) 1991-02-27
SE8601852L (en) 1986-10-24

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: GLAXO GROUP LTD

Effective date: 19930430