ES8800270A1 - Un procedimiento para preparar derivados de aminoacidos - Google Patents

Un procedimiento para preparar derivados de aminoacidos

Info

Publication number
ES8800270A1
ES8800270A1 ES552593A ES552593A ES8800270A1 ES 8800270 A1 ES8800270 A1 ES 8800270A1 ES 552593 A ES552593 A ES 552593A ES 552593 A ES552593 A ES 552593A ES 8800270 A1 ES8800270 A1 ES 8800270A1
Authority
ES
Spain
Prior art keywords
alkyl
hydrogen
protected
processes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES552593A
Other languages
English (en)
Other versions
ES552593A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858505481A external-priority patent/GB8505481D0/en
Priority claimed from GB858521016A external-priority patent/GB8521016D0/en
Priority claimed from GB858528367A external-priority patent/GB8528367D0/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of ES552593A0 publication Critical patent/ES552593A0/es
Publication of ES8800270A1 publication Critical patent/ES8800270A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/005—Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Abstract

PROCEDIMIENTO PARA PREPARAR DERIVADOS DE AMINOACIDOS. CONSISTE EN HACER REACCIONAR A UN COMPUESTO DE FOMULA (II) CON UN COMPUESTO DE FORMULA (III), EN UN DISOLVENTE INERTE (AGUA), EN PRESENCIA DE UNA BASE INORGANICA (BICARBONATO SODICO) U ORGANICA (PIRIDINA) Y CON ENFRIAMIENTO, PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. SIENDO: R ELEVADO A 1, H, AMINO Y OTROS; R ELEVADO A 2 Y R ELEVADO A 3, H, CARBOXI O CARBOXI PROTEGIDO; R ELEVADO A 4, ALQUILO INFERIOR, AMINO-ALQUILO INFERIOR Y OTRAS; R ELEVADO A 5, H O ALQUILO INFERIOR; Y R ELEVADO A 6, H, ARALQUILO INFERIOR Y OTROS. SE UTILIZAN RESTAURADORES DE LAS CELULAS DE LA MEDULA OSEA EN HOSPEDANTES INMUNODEFICIENTES. *FORMULA*
ES552593A 1985-03-04 1986-03-03 Un procedimiento para preparar derivados de aminoacidos Expired ES8800270A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB858505481A GB8505481D0 (en) 1985-03-04 1985-03-04 Compound fr-900490
GB858521016A GB8521016D0 (en) 1985-08-22 1985-08-22 Asparagine derivatives
GB858528367A GB8528367D0 (en) 1985-11-18 1985-11-18 Amino acid derivatives

Publications (2)

Publication Number Publication Date
ES552593A0 ES552593A0 (es) 1987-11-01
ES8800270A1 true ES8800270A1 (es) 1987-11-01

Family

ID=27262601

Family Applications (1)

Application Number Title Priority Date Filing Date
ES552593A Expired ES8800270A1 (es) 1985-03-04 1986-03-03 Un procedimiento para preparar derivados de aminoacidos

Country Status (14)

Country Link
US (1) US4743614A (es)
EP (1) EP0193904B1 (es)
KR (1) KR860007203A (es)
CN (1) CN86101394A (es)
AT (1) ATE61340T1 (es)
AU (1) AU5410786A (es)
DE (1) DE3677798D1 (es)
DK (1) DK96786A (es)
ES (1) ES8800270A1 (es)
FI (1) FI860878A (es)
GR (1) GR860556B (es)
HU (1) HUT40403A (es)
NO (1) NO860791L (es)
PT (1) PT82134B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2088826B1 (es) * 1995-02-10 1997-06-01 Taguidell Sociedad Limitada Procedimiento de obtencion de las diaminas putrescina y cadaverina a partir de productos naturales tratados, su uso como aditivo en abonos, y abono correspondiente.
NZ331272A (en) * 1996-02-09 2000-01-28 Black James Foundation Histamine H3 receptor ligands
DE69734783T2 (de) * 1996-07-24 2006-08-17 Buchardt, Dorte Peptidnukleinsäuren mit erhöhter bindungsaffinität, sequenzspezifität und löslichkeit
US6436904B1 (en) * 1999-01-25 2002-08-20 Elan Pharmaceuticals, Inc. Compounds which inhibit leukocyte adhesion mediated by VLA-4
US20020147229A1 (en) * 2000-08-17 2002-10-10 Allerton Charlotte Moira Norfor Pharmaceuticals
US6949577B2 (en) * 2000-09-13 2005-09-27 Pfizer, Inc. Pharmaceuticals
US10435356B1 (en) 2007-09-18 2019-10-08 Thermolife International, Llc Amino acid compositions
US8569368B2 (en) 2007-09-18 2013-10-29 Thermolife International, Llc Amino acid compounds
US8455531B2 (en) 2007-09-18 2013-06-04 Thermolife International, Llc Amino acid compositions
US8466187B2 (en) 2007-09-18 2013-06-18 Thermolife International, Llc Amino acid compositions
US8048921B2 (en) * 2007-09-18 2011-11-01 Ronald Kramer Amino acid compounds
US10426750B1 (en) 2007-09-18 2019-10-01 Thermolife International, Llc Amino acid supplement formulations
US7777074B2 (en) 2007-09-18 2010-08-17 Thermolife International, Llc Amino acid compounds
US10646508B1 (en) 2007-09-18 2020-05-12 Thermolife International, Llc Method of safely administering nitrate dietary supplements and compositions
US8569369B2 (en) 2007-09-18 2013-10-29 Thermolife International, Llc Amino acid compounds
PL2696865T3 (pl) 2011-04-13 2017-07-31 Thermolife International, Llc Sposoby zastosowania N-acetylo beta-alaniny
CN102241600B (zh) * 2011-05-13 2014-06-11 嘉兴市博源生物化工科技有限公司 2-氨基丁酸的制备方法
CN108929314B (zh) * 2017-05-27 2021-02-12 首都医科大学 3r-吲哚甲基-6s-酸性氨基酸修饰的哌嗪-2,5-二酮，其合成，活性和应用
US11865139B2 (en) 2020-11-12 2024-01-09 Thermolife International, Llc Method of treating migraines and headaches

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2993918A (en) * 1956-04-02 1961-07-25 John J Mccabe Jr Novel compositions of matter and methods for preparing them
US4001267A (en) * 1975-09-22 1977-01-04 The Upjohn Company Feldamycic acid
US4145337A (en) * 1977-10-11 1979-03-20 Hoffmann-La Roche Inc. Aminoethylglycine containing polypeptides
US4137416A (en) * 1978-01-05 1979-01-30 American Cyanamid Company 2-Acylamidoethyl-2-imidazolines
ZA802552B (en) * 1979-05-21 1981-04-29 Ici Ltd 1-phenyl-2-aminoethanol derivatives
JPS58170479A (ja) * 1982-03-30 1983-10-07 Sanraku Inc ジペプチダ−ゼ阻害剤
DE3219113A1 (de) * 1982-05-21 1983-11-24 Bayer Ag, 5090 Leverkusen Verwendung von n-substituierten 2,3-diaminocarbonsaeuren in arzneimitteln und ihre herstellung

Also Published As

Publication number Publication date
HUT40403A (en) 1986-12-28
US4743614A (en) 1988-05-10
DE3677798D1 (de) 1991-04-11
NO860791L (no) 1986-09-05
AU5410786A (en) 1986-09-11
ES552593A0 (es) 1987-11-01
FI860878A (fi) 1986-09-05
GR860556B (en) 1986-06-10
CN86101394A (zh) 1986-12-03
DK96786A (da) 1986-09-05
EP0193904A2 (en) 1986-09-10
PT82134B (en) 1987-08-10
PT82134A (en) 1986-04-01
DK96786D0 (da) 1986-03-03
EP0193904B1 (en) 1991-03-06
ATE61340T1 (de) 1991-03-15
EP0193904A3 (en) 1988-09-07
FI860878A0 (fi) 1986-03-03
KR860007203A (ko) 1986-10-08

Similar Documents

Publication Publication Date Title
ES8800270A1 (es) Un procedimiento para preparar derivados de aminoacidos
AU2983889A (en) 3-alkenyl-1-azabicyclo {3.2.0} hept-2-ene-2-carboxylic acid compounds
NO178697C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrazolopyridin-forbindelser
IE872329L (en) New cephem compounds and processes for preparation thereof
ATE48001T1 (de) Cephemverbindungen, verfahren zu ihrer herstellung und ihre pharmazeutischen praeparate.
AU3583989A (en) New cephem compounds and processes for preparation thereof
ES8405006A1 (es) Un procedimiento para la preparacion de derivados del acido tetrahidrofurancarboxilico.
EP0306863A3 (en) New cephem compounds and processes for preparation thereof