ES8707512A1 - Procedimiento para preparar 6-etoxi-4-metil-benzotiazol-2 (3h)-ona - Google Patents

Procedimiento para preparar 6-etoxi-4-metil-benzotiazol-2 (3h)-ona

Info

Publication number
ES8707512A1
ES8707512A1 ES544797A ES544797A ES8707512A1 ES 8707512 A1 ES8707512 A1 ES 8707512A1 ES 544797 A ES544797 A ES 544797A ES 544797 A ES544797 A ES 544797A ES 8707512 A1 ES8707512 A1 ES 8707512A1
Authority
ES
Spain
Prior art keywords
ethoxy
benzothiazol
methyl
processes
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES544797A
Other languages
English (en)
Other versions
ES544797A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES544797A0 publication Critical patent/ES544797A0/es
Publication of ES8707512A1 publication Critical patent/ES8707512A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR 6-ETOXI-4-METIL-BENZOTIAZOL-2(3H)-ONA. CONSISTE EN CICLIZAR EL 2-AMINOTIOFENOL DE FORMULA (II) CON UN DERIVADO DE ACIDO CARBONICO DE FORMULA (III) DONDE X1 Y X2 SON IGUALES O DIFERENTES Y SIGNIFICAN ATOMOS DE HALOGENO O EL GRUPO 1-IMIDAZOLILO 1,2,4-TRIAZOL-4-ILO, 1,2,4-TRIAZOL-1-ILO Y OTROS, A TEMPERATURA ENTRE 0 Y 150JC, CON EL EMPLEO DE UN ESTER DE ACIDO CLOROCARBONICO, PARA FORMAR UN COMPUESTO INTERMEDIO DE FORMULA (IV), DONDE R ES UN RADICAL ALQUILO CON C 1 A 10 O UN RADICAL ARILO O ARALQUILO CON C 1 A 3, QUE SE CICLIZA A CONTINUACION EN PRESENCIA DE CATALIZADORES ACIDOS ENTRE 20 Y 150JC PARA OBTENER 6-ETOXI-4-METIL-BENZOTIAZOL-2(3H)-ONA DE FORMULA (I). TIENE APLICACIONES COMO ANALGESICO Y ANTIPIRETICO.
ES544797A 1983-12-17 1985-07-02 Procedimiento para preparar 6-etoxi-4-metil-benzotiazol-2 (3h)-ona Expired ES8707512A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833345702 DE3345702A1 (de) 1983-12-17 1983-12-17 Neues benzothiazol-2(3h)-on, verfahren zur herstellung und diese verbindung enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
ES544797A0 ES544797A0 (es) 1986-02-01
ES8707512A1 true ES8707512A1 (es) 1986-02-01

Family

ID=6217230

Family Applications (4)

Application Number Title Priority Date Filing Date
ES538601A Expired ES8607957A1 (es) 1983-12-17 1984-12-14 Procedimiento para preparar 6-etoxi-4-metil-benzotiazol-2(3h)-ona
ES544795A Expired ES8707510A1 (es) 1983-12-17 1985-07-02 Procedimiento para preparar 6-etoxi-4-metil-benzotiazol-2(3h)-ona
ES544797A Expired ES8707512A1 (es) 1983-12-17 1985-07-02 Procedimiento para preparar 6-etoxi-4-metil-benzotiazol-2 (3h)-ona
ES544796A Expired ES8707511A1 (es) 1983-12-17 1985-07-02 Procedimiento para preparar 6-etoxi-4-metil-benzotiazol-2 (3h)-ona

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES538601A Expired ES8607957A1 (es) 1983-12-17 1984-12-14 Procedimiento para preparar 6-etoxi-4-metil-benzotiazol-2(3h)-ona
ES544795A Expired ES8707510A1 (es) 1983-12-17 1985-07-02 Procedimiento para preparar 6-etoxi-4-metil-benzotiazol-2(3h)-ona

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES544796A Expired ES8707511A1 (es) 1983-12-17 1985-07-02 Procedimiento para preparar 6-etoxi-4-metil-benzotiazol-2 (3h)-ona

Country Status (15)

Country Link
EP (1) EP0152574A1 (es)
JP (1) JPS60146883A (es)
KR (1) KR850004744A (es)
AU (1) AU3684384A (es)
DD (1) DD232273A5 (es)
DE (1) DE3345702A1 (es)
DK (1) DK597684A (es)
ES (4) ES8607957A1 (es)
FI (1) FI844949L (es)
GR (1) GR81211B (es)
HU (1) HU190660B (es)
IL (1) IL73818A0 (es)
NO (1) NO845033L (es)
PT (1) PT79675B (es)
ZA (1) ZA849746B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2627681B2 (ja) * 1990-07-18 1997-07-09 同仁医薬化工株式会社 マイコプラズマ・ニューモニエ診断用試薬

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2927352A1 (de) * 1979-07-06 1981-02-05 Thomae Gmbh Dr K In 6-stellung substituierte benzothiazol-2(3h)-one enthaltende arzneimittel
DE3017977A1 (de) * 1980-05-10 1981-11-19 Dr. Karl Thomae Gmbh, 7950 Biberach Neue substituierte 2(3h)-benzothiazolone
DE3017153A1 (de) * 1980-05-05 1981-11-12 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von 2-hydroxybenzthiazolen

Also Published As

Publication number Publication date
AU3684384A (en) 1985-07-04
ES538601A0 (es) 1985-11-01
PT79675A (de) 1985-01-01
ZA849746B (en) 1986-08-27
FI844949L (fi) 1985-06-18
ES8707511A1 (es) 1986-02-01
ES544797A0 (es) 1986-02-01
JPS60146883A (ja) 1985-08-02
DE3345702A1 (de) 1985-06-27
DK597684A (da) 1985-06-18
NO845033L (no) 1985-06-18
IL73818A0 (en) 1985-03-31
ES544796A0 (es) 1986-02-01
FI844949A0 (fi) 1984-12-14
ES8607957A1 (es) 1985-11-01
EP0152574A1 (de) 1985-08-28
DK597684D0 (da) 1984-12-13
ES544795A0 (es) 1986-02-01
KR850004744A (ko) 1985-07-27
DD232273A5 (de) 1986-01-22
ES8707510A1 (es) 1986-02-01
GR81211B (en) 1985-04-08
HUT36811A (en) 1985-10-28
HU190660B (en) 1986-10-28
PT79675B (de) 1986-12-10

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