ES8704935A1 - Procedimiento para preparar derivados de fenilpiperazina - Google Patents
Procedimiento para preparar derivados de fenilpiperazinaInfo
- Publication number
- ES8704935A1 ES8704935A1 ES549076A ES549076A ES8704935A1 ES 8704935 A1 ES8704935 A1 ES 8704935A1 ES 549076 A ES549076 A ES 549076A ES 549076 A ES549076 A ES 549076A ES 8704935 A1 ES8704935 A1 ES 8704935A1
- Authority
- ES
- Spain
- Prior art keywords
- substituted phenyl
- piperazine derivatives
- phenyl piperazine
- aggression
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Anesthesiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR DERIVADOS DE FENILPIPERAZINA. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UNA FENILPIPERAZINA DE FORMULA (III), EN UN DISOLVENTE ADECUADO, TAL COMO TETRAHIDROFURANO, ESTERES Y OTROS, Y A UNA TEMPERATURA COMPRENDIDA ENTRE 50 Y 200JC, PARA OBTENER DERIVADOS DE FENILPIPERAZINA DE FORMULA (I) EN DONDE R1 SIGNIFICA HIDROGENO O FENILO; R2 SIGNIFICA ALQUILO DE C 1 A 6, ESTANDO EXCLUIDO EL SIGNIFICADO SIMULTANEO DE R1 IGUAL A HIDROGENO Y R2 IGUAL A METILO. TIENEN APLICACION EN EL CAMPO DE LA VETERINARIA POR PROVOCAR EN ANIMALES UNA INHIBICION A LA AGRESION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843442570 DE3442570A1 (de) | 1984-11-22 | 1984-11-22 | Neue substituierte phenylpiperazinderivate, verfahren zu deren herstellung und die verwendung substituierter phenylpiperazinderivate als aggressionshemmer fuer tiere |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8704935A1 true ES8704935A1 (es) | 1987-04-16 |
ES549076A0 ES549076A0 (es) | 1987-04-16 |
Family
ID=6250865
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES549076A Expired ES8704935A1 (es) | 1984-11-22 | 1985-11-20 | Procedimiento para preparar derivados de fenilpiperazina |
ES557313A Expired ES8801246A1 (es) | 1984-11-22 | 1987-01-14 | Procedimiento para preparar derivados de fenilpirazina |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES557313A Expired ES8801246A1 (es) | 1984-11-22 | 1987-01-14 | Procedimiento para preparar derivados de fenilpirazina |
Country Status (14)
Country | Link |
---|---|
US (1) | US4746661A (es) |
EP (1) | EP0182247A1 (es) |
JP (1) | JPS61129167A (es) |
KR (1) | KR860004051A (es) |
CN (1) | CN85108214A (es) |
AU (1) | AU5025285A (es) |
DE (1) | DE3442570A1 (es) |
DK (1) | DK538185A (es) |
ES (2) | ES8704935A1 (es) |
GR (1) | GR852799B (es) |
HU (1) | HU195803B (es) |
IL (1) | IL77113A0 (es) |
PT (1) | PT81529B (es) |
ZA (1) | ZA858936B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4803203A (en) * | 1986-11-05 | 1989-02-07 | Warner-Lambert Company | Phenyl and heterocyclic piperazinyl alkoxy-benzheterocyclic compounds as antipsychotic agents |
US5006528A (en) * | 1988-10-31 | 1991-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
EP2162135A4 (en) * | 2007-05-21 | 2012-02-22 | Reviva Pharmaceuticals Inc | COMPOSITIONS, SYNTHESIS AND METHOD FOR THE APPLICATION OF ATTAINED CHINOLINONE-BASED ANTIPSYCHOTICS |
KR20100045983A (ko) * | 2007-06-29 | 2010-05-04 | 에모리 유니버시티 | 신경보호를 위한 nmda 수용체 길항물질 |
WO2009137843A2 (en) * | 2008-05-09 | 2009-11-12 | Emory University | Nmda receptor antagonists for the treatment of neuropsychiatric disorders |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5089221A (es) * | 1973-12-10 | 1975-07-17 | ||
JPS54130587A (en) * | 1978-03-30 | 1979-10-09 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
DE2853996A1 (de) * | 1978-12-14 | 1980-07-03 | Hoechst Ag | Neue substituierte phenylpiperazinderivate und verfahren zu deren herstellung |
DE2960178D1 (en) * | 1978-06-06 | 1981-04-09 | Hoechst Ag | New substituted phenylpiperazine derivatives, pharmaceutical compositions containing them and process for their preparation |
DE2827566A1 (de) * | 1978-06-23 | 1980-01-10 | Boehringer Mannheim Gmbh | 1,2-dihydro-chinolin-2-on-derivate und verfahren zu ihrer herstellung |
JPS6122351A (ja) * | 1984-07-10 | 1986-01-30 | Toshiba Corp | アモルフアスシリコン感光体 |
JPS6164186A (ja) * | 1984-09-06 | 1986-04-02 | 三菱電機株式会社 | 電子部品リ−ドレスパツケ−ジの実装構造 |
-
1984
- 1984-11-22 DE DE19843442570 patent/DE3442570A1/de not_active Withdrawn
- 1984-11-22 CN CN198585108214A patent/CN85108214A/zh active Pending
-
1985
- 1985-11-12 EP EP85114340A patent/EP0182247A1/de not_active Withdrawn
- 1985-11-18 HU HU854379A patent/HU195803B/hu unknown
- 1985-11-20 GR GR852799A patent/GR852799B/el unknown
- 1985-11-20 ES ES549076A patent/ES8704935A1/es not_active Expired
- 1985-11-21 DK DK538185A patent/DK538185A/da not_active Application Discontinuation
- 1985-11-21 IL IL77113A patent/IL77113A0/xx unknown
- 1985-11-21 KR KR1019850008705A patent/KR860004051A/ko not_active Application Discontinuation
- 1985-11-21 AU AU50252/85A patent/AU5025285A/en not_active Abandoned
- 1985-11-21 PT PT81529A patent/PT81529B/pt unknown
- 1985-11-21 JP JP60259932A patent/JPS61129167A/ja active Pending
- 1985-11-21 ZA ZA858936A patent/ZA858936B/xx unknown
-
1987
- 1987-01-14 ES ES557313A patent/ES8801246A1/es not_active Expired
- 1987-02-26 US US07/021,523 patent/US4746661A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE3442570A1 (de) | 1986-05-22 |
PT81529A (de) | 1985-12-01 |
KR860004051A (ko) | 1986-06-16 |
IL77113A0 (en) | 1986-04-29 |
EP0182247A1 (de) | 1986-05-28 |
JPS61129167A (ja) | 1986-06-17 |
ES557313A0 (es) | 1988-01-01 |
AU5025285A (en) | 1986-05-29 |
PT81529B (de) | 1987-06-12 |
ZA858936B (en) | 1986-07-30 |
HUT39742A (en) | 1986-10-29 |
DK538185A (da) | 1986-05-23 |
ES8801246A1 (es) | 1988-01-01 |
ES549076A0 (es) | 1987-04-16 |
DK538185D0 (da) | 1985-11-21 |
US4746661A (en) | 1988-05-24 |
GR852799B (es) | 1986-03-19 |
HU195803B (en) | 1988-07-28 |
CN85108214A (zh) | 1986-08-20 |
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