ES8702946A1 - Procedimiento para preparar d-aminoacido-transaminasa - Google Patents

Procedimiento para preparar d-aminoacido-transaminasa

Info

Publication number
ES8702946A1
ES8702946A1 ES550234A ES550234A ES8702946A1 ES 8702946 A1 ES8702946 A1 ES 8702946A1 ES 550234 A ES550234 A ES 550234A ES 550234 A ES550234 A ES 550234A ES 8702946 A1 ES8702946 A1 ES 8702946A1
Authority
ES
Spain
Prior art keywords
delta
amino acids
amino acid
acids
acid transaminase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES550234A
Other languages
English (en)
Other versions
ES550234A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES550234A0 publication Critical patent/ES550234A0/es
Publication of ES8702946A1 publication Critical patent/ES8702946A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y10S435/836—Bacillus licheniformis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR D-AMINOACIDO TRANSAMINASA, SE TRATA DE UNA DESAMINACION OXIDATIVA EN LA QUE SE FORMA PEROXIDO DE HIDROGENO COMO PRODUCTO SECUNDARIO. LA ENZIMA SE FORMA A PARTIR DE LA CEPA BACTERIANA <BACILLUS LICHENIFORMIS ATCC 9945>, QUE SE FERMENTA EN CONDICIONES AEROBIAS Y PUEDE SER AISLADA A PARTIR DE LAS CELULAS, DESPUES DE UNA DISGREGACION, SIRVIENDO LA TRANSFORMACION DE CEFALOSPORINA C (CPC) EN A-CETOACIDOS PARA DAR A-CETOADIPINIL-7-AMINOCEFALOSPORANICO COMO CRITERIO PARA EL DESCUBRIMIENTO DE LA FRACCION EN LA QUE SE ENCUENTRA LA ENZIMA. LA ENZIMA ES TAMBIEN APROPIADA PARA LA SEPARACION DE RACEMATOS DE D.L-AMINOACIDOS Y PARA LA DETECCION DE A-CETOACIDOS JUNTO A L-AMINOACIDOS.
ES550234A 1984-12-22 1985-12-20 Procedimiento para preparar d-aminoacido-transaminasa Expired ES8702946A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843447023 DE3447023A1 (de) 1984-12-22 1984-12-22 Neue d-aminosaeure-transaminase und ihre verwendung

Publications (2)

Publication Number Publication Date
ES550234A0 ES550234A0 (es) 1987-01-16
ES8702946A1 true ES8702946A1 (es) 1987-01-16

Family

ID=6253610

Family Applications (1)

Application Number Title Priority Date Filing Date
ES550234A Expired ES8702946A1 (es) 1984-12-22 1985-12-20 Procedimiento para preparar d-aminoacido-transaminasa

Country Status (9)

Country Link
US (1) US4745061A (es)
EP (1) EP0186035B1 (es)
JP (1) JPS61247382A (es)
AT (1) ATE70300T1 (es)
DE (2) DE3447023A1 (es)
DK (1) DK597485A (es)
ES (1) ES8702946A1 (es)
GR (1) GR853100B (es)
PT (1) PT81734B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4981789A (en) * 1987-03-18 1991-01-01 Merck & Co., Inc. One-step enzymatic conversion of cephalosporin C and derivatives to 7-aminocephalosporanic acid and derivatives
NL8702449A (nl) * 1987-10-14 1987-12-01 Stamicarbon Werkwijze voor de bereiding van een d-alfa-aminozuur uit het overeenkomstige alfa-ketozuur.
US5316943A (en) * 1988-06-14 1994-05-31 Kidman Gene E Racemic conversion of using a transaminase
DE3842025A1 (de) * 1988-12-14 1990-07-05 Hoechst Ag Verfahren zur herstellung von l-phosphinothricin
US5169780A (en) * 1989-06-22 1992-12-08 Celgene Corporation Enantiomeric enrichment and stereoselective synthesis of chiral amines
US5104800A (en) * 1989-06-27 1992-04-14 Merck & Co., Inc. One-step cephalosporin c amidase enzyme
US5229274A (en) * 1989-06-27 1993-07-20 Merck & Co., Inc. Gene encoding one step cephalosporin C amidase and expression thereof in recombinant bacillus
CA2021299C (en) * 1989-07-19 1999-08-17 Jeffrey T. Vicenzi Enzymatic oxidation of ceph c to glutaryl-7-amino cephalosporanic acid
US4912042A (en) * 1989-08-17 1990-03-27 Eastman Kodak Company Preparation of D-malic acid or derivative
IT1252308B (it) * 1990-12-21 1995-06-08 Antibioticos Spa Procedimento enzimatico per la produzione di acido 7- amminocefalosporanico e derivati
EP0857790B1 (en) * 1995-10-23 2005-08-17 Kaneka Corporation Process for producing optically active amino compounds
US6337190B1 (en) 1999-12-17 2002-01-08 Development Center For Biotechnology D-amino acid aminotransferase for simultaneously producing glutaryl-7-aminocephalosporanic acid and D-amino acid
DE60115267T2 (de) * 2000-09-22 2006-08-17 Bristol-Myers Squibb Co. Glutaryl-cephalosporin-amidase aus pseudomonas diminuta bs-203
KR20040014498A (ko) 2001-04-19 2004-02-14 바이오퍼마 무르시아, 에스.에이. 세팔로스포린 유도체의 제조 방법
US7297800B2 (en) 2001-12-27 2007-11-20 Ajinomoto Co., Inc. Process of producing glutamate derivatives
DE60332026D1 (de) 2002-08-26 2010-05-20 Ajinomoto Kk Ubstituierter alpha-ketosäure
EP2557160A3 (en) * 2002-12-09 2013-03-27 Ajinomoto Co., Inc. Mutated D-aminotransferase and method for producing optically active glutamic acid derivatives using the same
CN101603015B (zh) * 2008-06-13 2010-11-10 河北维尔康制药有限公司 一种地衣芽孢杆菌菌株及用途和用其生产聚γ-谷氨酸的方法
KR101307348B1 (ko) * 2010-11-02 2013-09-11 대상 주식회사 Ｌ―글루탐산 고생산능 코리네박테리움 글루타미쿰 변이 균주

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1385685A (en) * 1971-04-21 1975-02-26 Glaxo Lab Ltd Cephalosporin derivatives
DE3482982D1 (de) * 1983-09-01 1990-09-20 Genetics Inst Herstellung von l-aminosaeuren durch transaminierung.
DE3333453A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt L-aminosaeure-oxidase aus hefen der gattung cryptococcus, ihre herstellung und verwendung

Also Published As

Publication number Publication date
DE3447023A1 (de) 1986-06-26
EP0186035A2 (de) 1986-07-02
US4745061A (en) 1988-05-17
PT81734B (de) 1987-08-10
PT81734A (de) 1986-01-01
DE3584878D1 (de) 1992-01-23
JPS61247382A (ja) 1986-11-04
ATE70300T1 (de) 1991-12-15
DK597485A (da) 1986-06-23
ES550234A0 (es) 1987-01-16
GR853100B (es) 1986-04-18
DK597485D0 (da) 1985-12-20
EP0186035A3 (en) 1988-03-16
EP0186035B1 (de) 1991-12-11

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