DE3482982D1 - Herstellung von l-aminosaeuren durch transaminierung. - Google Patents
Herstellung von l-aminosaeuren durch transaminierung.Info
- Publication number
- DE3482982D1 DE3482982D1 DE8484110407T DE3482982T DE3482982D1 DE 3482982 D1 DE3482982 D1 DE 3482982D1 DE 8484110407 T DE8484110407 T DE 8484110407T DE 3482982 T DE3482982 T DE 3482982T DE 3482982 D1 DE3482982 D1 DE 3482982D1
- Authority
- DE
- Germany
- Prior art keywords
- transamination
- production
- amino acids
- acids
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/18—Multi-enzyme systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/12—Methionine; Cysteine; Cystine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/848—Escherichia
- Y10S435/849—Escherichia coli
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/528,730 US4518692A (en) | 1983-09-01 | 1983-09-01 | Production of L-amino acids by transamination |
US64364284A | 1984-08-23 | 1984-08-23 | |
US06/643,654 US4525454A (en) | 1983-09-01 | 1984-08-23 | Production of L-4-phenyl-2-aminobutanoic acid by transamination |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3482982D1 true DE3482982D1 (de) | 1990-09-20 |
Family
ID=27415006
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8484110407T Expired - Fee Related DE3482982D1 (de) | 1983-09-01 | 1984-08-31 | Herstellung von l-aminosaeuren durch transaminierung. |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0135846B1 (de) |
DE (1) | DE3482982D1 (de) |
HU (1) | HU193902B (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2152503B (en) * | 1984-01-05 | 1986-03-19 | Grace W R & Co | Process for producing l-phenylalanine |
US4783403A (en) * | 1984-02-08 | 1988-11-08 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing l-phenylalanine |
DE3423936A1 (de) * | 1984-06-29 | 1986-01-02 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von l-phenylalanin |
SE8502315L (sv) * | 1984-07-05 | 1986-01-06 | Grace W R & Co | Forbettrat transamineringsforfarande for framstellning av aminosyror |
US4859591A (en) * | 1984-07-05 | 1989-08-22 | W. R. Grace & Co.-Conn. | Transamination process for producing amino acids |
DE3447023A1 (de) * | 1984-12-22 | 1986-06-26 | Hoechst Ag, 6230 Frankfurt | Neue d-aminosaeure-transaminase und ihre verwendung |
DE3613952A1 (de) * | 1986-04-24 | 1987-10-29 | Hoechst Ag | Verfahren zur herstellung von l-aminosaeuren durch transaminierung |
DE3752311D1 (de) * | 1986-06-04 | 2000-04-27 | Hoechst Schering Agrevo Gmbh | Verfahren zur Herstellung von L-tertiär-Leucin durch Transaminierung |
FR2609712A1 (fr) * | 1987-01-16 | 1988-07-22 | Inst Nat Rech Chimique | Precurseurs et milieux les contenant pour la fabrication de l-aminoacides |
DE3842025A1 (de) * | 1988-12-14 | 1990-07-05 | Hoechst Ag | Verfahren zur herstellung von l-phosphinothricin |
US4950606A (en) * | 1989-06-22 | 1990-08-21 | Celgene Corporation | Enantiomeric enrichment and stereoselective synthesis of chiral amines |
DE4030578A1 (de) * | 1990-09-27 | 1992-04-16 | Hoechst Ag | Verfahren zur herstellung von l-phosphinothricin durch eine gekoppelte enzymatische reaktion |
EP0857790B1 (de) * | 1995-10-23 | 2005-08-17 | Kaneka Corporation | Verfahren zur herstellung optisch aktiver aminoverbindungen |
WO2000023609A1 (en) * | 1998-10-19 | 2000-04-27 | Nsc Technologies Llc | Transaminase biotransformation process employing glutamic acid |
DE60025799T2 (de) * | 1999-04-05 | 2006-10-19 | Sumitomo Chemical Co., Ltd. | Verfahren zur Herstellung von optisch aktiven Aminosäuren |
DE19919848A1 (de) * | 1999-04-30 | 2000-11-02 | Aventis Cropscience Gmbh | Verfahren zur Herstellung von L-Phosphinothricin durch enzymatische Transaminierung mit Aspartat |
US6365380B2 (en) | 2000-02-23 | 2002-04-02 | Pcbu Services, Inc. | Method for stereoselectively inverting a chiral center of a chemical compound using an enzyme and a metal catalyst |
EP1818411A1 (de) | 2006-02-13 | 2007-08-15 | Lonza AG | Verfahren zur Herstellung von optisch aktiven chiralen Aminen |
US7588923B2 (en) * | 2007-03-02 | 2009-09-15 | Richmond Chemical Corporation | Method to increase the yield and improve purification of products from transaminase reactions |
EP2828256B1 (de) * | 2012-03-23 | 2019-07-03 | Novartis AG | Chemisches verfahren zur herstellung von spiroindolonen und zwischenprodukte davon |
CN104185634B (zh) * | 2012-03-23 | 2017-05-03 | 诺华股份有限公司 | 制备螺旋吲哚酮和其中间体的化学工艺 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1227855B (de) * | 1960-07-12 | 1966-11-03 | Ichthyol Ges | Verfahren zur Herstellung von Enzymkoerpern fuer die Durchfuehrung enzymatischer Reaktionen |
US3183170A (en) * | 1961-10-03 | 1965-05-11 | Sanraku Ocean Kabushiki Kaisha | Method of l-amino acid manufacture |
FR1440438A (fr) * | 1965-07-13 | 1966-05-27 | Tanabe Seiyaku Co | Séparation d'amino-acides racémiques |
CH563344A5 (de) * | 1970-09-30 | 1975-06-30 | Nisshin Flour Milling Co | |
DE2927534A1 (de) * | 1979-07-07 | 1981-01-08 | Bayer Ag | Optisch reine heterocyclische aminosaeuren, verfahren zu ihrer herstellung und ihre verwendung |
GB2084155B (en) * | 1980-09-17 | 1984-01-11 | Grace W R & Co | Process for production of l-amino acids using immobilized microorganisms |
FR2509748B1 (fr) * | 1981-07-16 | 1985-07-05 | Santerre Orsan | Procede de production d'aminoacides en continu par emploi d'une souche bacterienne selectionnee adsorbee sur un support poreux et aminoacides obtenus par ledit procede |
US4600692A (en) * | 1983-02-10 | 1986-07-15 | Purification Engineering, Inc. | Immobilized cells for preparing phenylalanine |
GB2152503B (en) * | 1984-01-05 | 1986-03-19 | Grace W R & Co | Process for producing l-phenylalanine |
SE8502315L (sv) * | 1984-07-05 | 1986-01-06 | Grace W R & Co | Forbettrat transamineringsforfarande for framstellning av aminosyror |
-
1984
- 1984-08-31 HU HU843299A patent/HU193902B/hu unknown
- 1984-08-31 DE DE8484110407T patent/DE3482982D1/de not_active Expired - Fee Related
- 1984-08-31 EP EP84110407A patent/EP0135846B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
HU193902B (en) | 1987-12-28 |
EP0135846A3 (en) | 1986-12-10 |
EP0135846A2 (de) | 1985-04-03 |
EP0135846B1 (de) | 1990-08-16 |
HUT35281A (en) | 1985-06-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |