ES8702330A1 - Un procedimiento para preparar un derivado de 1,4-benzoquinona. - Google Patents
Un procedimiento para preparar un derivado de 1,4-benzoquinona.Info
- Publication number
- ES8702330A1 ES8702330A1 ES85539878A ES539878A ES8702330A1 ES 8702330 A1 ES8702330 A1 ES 8702330A1 ES 85539878 A ES85539878 A ES 85539878A ES 539878 A ES539878 A ES 539878A ES 8702330 A1 ES8702330 A1 ES 8702330A1
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- cardiac
- cerebral
- preparing
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000004057 1,4-benzoquinones Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000001997 phenyl group Chemical class [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 2
- 208000026935 allergic disease Diseases 0.000 abstract 2
- 230000007815 allergy Effects 0.000 abstract 2
- 230000000747 cardiac effect Effects 0.000 abstract 2
- UPUDVKWQBVIKBG-UHFFFAOYSA-N 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxyisoquinolin-2-ium;chloride Chemical compound [Cl-].C1=C(OCC)C(OCC)=CC=C1CC1=[NH+]C=CC2=CC(OCC)=C(OCC)C=C12 UPUDVKWQBVIKBG-UHFFFAOYSA-N 0.000 abstract 1
- 239000004129 EU approved improving agent Substances 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 239000012190 activator Substances 0.000 abstract 1
- 239000000043 antiallergic agent Substances 0.000 abstract 1
- 150000001555 benzenes Chemical class 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 230000003727 cerebral blood flow Effects 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
- C07C50/30—Quinones containing groups having oxygen atoms singly bound to carbon atoms with polycyclic non-condensed quinoid structure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/30—Compounds having groups
- C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
- C07C45/305—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation with halogenochromate reagents, e.g. pyridinium chlorochromate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
- C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
- C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
- C07C46/06—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
- C07C46/08—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring with molecular oxygen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
- C07C46/10—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
- C07C50/28—Quinones containing groups having oxygen atoms singly bound to carbon atoms with monocyclic quinoid structure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR DERTIVADOS DE 1,4-BENZOQUINONA. SE OXIDA UN FENOL DE FORMULA GENERAL (I) EN UN DISOLVENTE INERTE, EN PRESENCIA DE UN AGENTE OXIDANTE, A UNA TEMPERATURA ENTRE LA DEL AMBIENTE Y 60JC Y DURANTE 1 A 10 HORAS. ESTOS COMPUESTOS SON APLICABLES PARA ACTIVAR EL FLUJO SANGUINEO CARDIACO Y CEREBRAL Y PARA PREVENIR LA ISQUEMIA CEREBRAL, ASI COMO PARA COMBATIR LAS ALERGIAS DE REACCION LENTA.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59013037A JPS60156610A (ja) | 1984-01-26 | 1984-01-26 | アラキドン酸5−リポキシゲナ−ゼ阻害剤 |
JP59143858A JPS6122041A (ja) | 1984-07-10 | 1984-07-10 | 1,4−ベンゾキノン誘導体 |
JP14487684A JPS6124536A (ja) | 1984-07-11 | 1984-07-11 | 1,4−ベンゾキノン誘導体 |
JP59230683A JPS61109714A (ja) | 1984-10-31 | 1984-10-31 | アラキドン酸5−リポキシゲナ−ゼ阻害剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8702330A1 true ES8702330A1 (es) | 1986-12-16 |
ES539878A0 ES539878A0 (es) | 1986-12-16 |
Family
ID=27455918
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES85539878A Expired ES8702330A1 (es) | 1984-01-26 | 1985-01-25 | Un procedimiento para preparar un derivado de 1,4-benzoquinona. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0151995B1 (es) |
KR (1) | KR910007075B1 (es) |
DE (1) | DE3586910T2 (es) |
DK (1) | DK34185A (es) |
ES (1) | ES8702330A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100325798B1 (ko) * | 1998-01-14 | 2002-02-25 | 한병훈 | 암전이 억제작용 및 항혈전 작용이 있는 벤조퀴논류 화합물 |
FR2835523B1 (fr) * | 2002-02-06 | 2004-04-16 | Servier Lab | Nouveaux derives de 3-aryl-2,5-dihydroxy-1,4-benzoquinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4393075A (en) * | 1980-04-14 | 1983-07-12 | Takeda Chemical Industries, Ltd. | Quinone compounds and their use in suppressing the production of SRS-A in mammals |
JPS56150014A (en) * | 1980-04-21 | 1981-11-20 | Takeda Chem Ind Ltd | Antiallergic agent |
JPS5750935A (en) * | 1980-09-12 | 1982-03-25 | Otsuka Pharmaceut Co Ltd | 1,4-benzoquinone derivative |
-
1985
- 1985-01-25 ES ES85539878A patent/ES8702330A1/es not_active Expired
- 1985-01-25 EP EP85100789A patent/EP0151995B1/en not_active Expired - Lifetime
- 1985-01-25 DK DK34185A patent/DK34185A/da not_active Application Discontinuation
- 1985-01-25 DE DE8585100789T patent/DE3586910T2/de not_active Expired - Fee Related
- 1985-01-26 KR KR1019850000496A patent/KR910007075B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0151995A2 (en) | 1985-08-21 |
DE3586910T2 (de) | 1993-05-19 |
KR850005396A (ko) | 1985-08-24 |
DK34185D0 (da) | 1985-01-25 |
EP0151995A3 (en) | 1987-04-22 |
DK34185A (da) | 1985-07-27 |
EP0151995B1 (en) | 1992-12-23 |
KR910007075B1 (ko) | 1991-09-16 |
DE3586910D1 (de) | 1993-02-04 |
ES539878A0 (es) | 1986-12-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19971001 |