ES8700236A1 - Un procedimiento para preparar una sal de quelato con hete- rociclo nitrogenado - Google Patents
Un procedimiento para preparar una sal de quelato con hete- rociclo nitrogenadoInfo
- Publication number
- ES8700236A1 ES8700236A1 ES545395A ES545395A ES8700236A1 ES 8700236 A1 ES8700236 A1 ES 8700236A1 ES 545395 A ES545395 A ES 545395A ES 545395 A ES545395 A ES 545395A ES 8700236 A1 ES8700236 A1 ES 8700236A1
- Authority
- ES
- Spain
- Prior art keywords
- radionuclide
- dihydropyridine
- brain
- pyridinium salt
- elimination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
- C07F13/005—Compounds without a metal-carbon linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
Abstract
PROCEDIMIENTO PARA PREPARAR UNA SAL DE QUELATO CON HETEROCICLO NITROGENADO. CONSISTE EN PROPORCIONAR UN TIPO DE SISTEMA DE SUMINISTRO REDOX O QUIMICO, DIHIDROPIRIDINA '' SAL DE PIRIDINIO, PARA EL SUMINISTRO ESPECIFICO, EN CUANTO AL SITIO, DE UN RADIONUCLEIDO AL CEREBRO. UN AGENTE QUELANTE CON FUNCION AMINO PRIMARIA, SECUNDARIA O TERCIARIA, EN EL QUE DICHA FUNCION ESTA REEMPLAZADA POR UN SISTEMA REDOX DE DIHIDROPIRINA '' SAL DE PIRIDINIO Y COMPLEJARSE CON UN RADIONUCLEIDO PARA PROPORCIONAR UN PRODUCTO RADIOFARMACEUTICO QUE ATRAVIESA LA BARRERA SANGRE-CEREBRO. SE USA EN ESCINTIGRAFIA Y TECNICAS RADIOGRAFICAS SIMILARES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63238384A | 1984-07-19 | 1984-07-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8700236A1 true ES8700236A1 (es) | 1986-10-01 |
ES545395A0 ES545395A0 (es) | 1986-10-01 |
Family
ID=24535323
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES545395A Expired ES8700236A1 (es) | 1984-07-19 | 1985-07-19 | Un procedimiento para preparar una sal de quelato con hete- rociclo nitrogenado |
ES552090A Expired ES8705389A1 (es) | 1984-07-19 | 1986-02-17 | Un procedimiento para preparar una sal de quelato con heterociclo nitrogenado |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES552090A Expired ES8705389A1 (es) | 1984-07-19 | 1986-02-17 | Un procedimiento para preparar una sal de quelato con heterociclo nitrogenado |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0191788A1 (es) |
JP (1) | JPS61112054A (es) |
KR (1) | KR900008168B1 (es) |
AU (1) | AU4632085A (es) |
CA (1) | CA1266864A (es) |
DK (1) | DK124686A (es) |
ES (2) | ES8700236A1 (es) |
FI (1) | FI861119A0 (es) |
GR (1) | GR851793B (es) |
IL (1) | IL75845A0 (es) |
NO (1) | NO860980L (es) |
PT (1) | PT80842B (es) |
WO (1) | WO1986000897A1 (es) |
ZA (1) | ZA855477B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5071636A (en) * | 1987-12-29 | 1991-12-10 | Nihon Medi-Physics Co., Ltd. | Chelating compounds and their use |
SE526214C2 (sv) * | 2003-02-28 | 2005-07-26 | Amersham Biosciences Ab | Ett sätt att generera metallkelaterande affinitetsligander |
KR101033209B1 (ko) * | 2004-12-31 | 2011-05-06 | 주식회사 효성 | 분사성을 향상시킨 폴리에스테르 분섬사의 제조방법 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4444690A (en) * | 1982-02-25 | 1984-04-24 | University Patents, Inc. | Technetium chelates |
EP0222425A3 (en) * | 1982-05-18 | 1988-09-21 | University Of Florida | Brain-specific drug delivery |
-
1985
- 1985-07-15 AU AU46320/85A patent/AU4632085A/en not_active Abandoned
- 1985-07-15 EP EP85903750A patent/EP0191788A1/en not_active Withdrawn
- 1985-07-15 WO PCT/US1985/001333 patent/WO1986000897A1/en not_active Application Discontinuation
- 1985-07-18 KR KR8505136A patent/KR900008168B1/ko active IP Right Grant
- 1985-07-18 GR GR851793A patent/GR851793B/el unknown
- 1985-07-18 IL IL75845A patent/IL75845A0/xx unknown
- 1985-07-19 ZA ZA855477A patent/ZA855477B/xx unknown
- 1985-07-19 CA CA000487166A patent/CA1266864A/en not_active Expired - Fee Related
- 1985-07-19 PT PT80842A patent/PT80842B/pt unknown
- 1985-07-19 JP JP60160039A patent/JPS61112054A/ja active Pending
- 1985-07-19 ES ES545395A patent/ES8700236A1/es not_active Expired
-
1986
- 1986-02-17 ES ES552090A patent/ES8705389A1/es not_active Expired
- 1986-03-14 NO NO860980A patent/NO860980L/no unknown
- 1986-03-18 FI FI861119A patent/FI861119A0/fi not_active Application Discontinuation
- 1986-03-18 DK DK124686A patent/DK124686A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL75845A0 (en) | 1985-11-29 |
PT80842B (en) | 1987-05-27 |
ES8705389A1 (es) | 1987-05-01 |
ES545395A0 (es) | 1986-10-01 |
PT80842A (en) | 1985-08-01 |
NO860980L (no) | 1986-05-06 |
FI861119A (fi) | 1986-03-18 |
KR870000935A (ko) | 1987-03-10 |
ZA855477B (en) | 1987-03-25 |
EP0191788A1 (en) | 1986-08-27 |
AU4632085A (en) | 1986-02-25 |
GR851793B (es) | 1985-11-26 |
JPS61112054A (ja) | 1986-05-30 |
ES552090A0 (es) | 1987-05-01 |
WO1986000897A1 (en) | 1986-02-13 |
KR900008168B1 (en) | 1990-11-05 |
DK124686D0 (da) | 1986-03-18 |
CA1266864A (en) | 1990-03-20 |
DK124686A (da) | 1986-05-20 |
FI861119A0 (fi) | 1986-03-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA906634B (en) | Chelating agent for forming complexes with radioactive isotopes,metal complexes thereof and use thereof in diagnosis and therepy | |
IE791203L (en) | Radioactive scanning agents with hydroquinone as stabilizer | |
ATE76401T1 (de) | Durch estergruppen substituierte diamindithiole und davon abgeleitete radioaktiv markierte komplexe. | |
GB1489330A (en) | Stable diagnostic reagents | |
IT1214651B (it) | Composti chelanti per la riduzione di ioni metallici contenuti nei tessuti corporei, in particolare ferro, composizioni farmaceutiche contenenti tali composti e procedimento di preparazione | |
KR840002645A (ko) | 안정된 방사성 진단제와 이를 위한 비방사성 캐리어 | |
ATE179076T1 (de) | Chelatbildner vom typ xn 1?s 1?o 1? für radioaktive isotope, deren metallkomplexe und ihre verwendung in diagnostik und therapie | |
WO1997010852A3 (de) | Bifunktionelle sulfidhaltige sulfonamid-chelatbildner vom typ xsns für radioaktive isotope | |
JPS5750928A (en) | Diagnostic agent for scanning bone | |
CA1324317C (en) | Stable radiodiagnostic products, and the preparation thereof | |
ES8700236A1 (es) | Un procedimiento para preparar una sal de quelato con hete- rociclo nitrogenado | |
ES8704900A1 (es) | Un procedimiento para preparar una sal de quelato con piridina | |
GB2156345B (en) | Alkylamine salts of 3,5-diacetylamino-2,4,6-triiodobenzoic acid as x-ray contrast agents | |
Colombetti et al. | Effect of chemical and radiochemical impurities from eluants on 99mTc-labeling efficiency | |
DE3367853D1 (en) | Radiographic imaging agents | |
ZA851409B (en) | Bis(aminomethyl)bicyclo(2.2.1)heptanes useful as metal ion control agents and radioactive metals complexed therewith | |
DE69117741D1 (de) | Neue vorangeordnete sechszähnige liganden verwendbar in röntgenologischen bildformenden wirkstoffen | |
IL74386A0 (en) | Bis(aminomethyl)bicyclo(2,2,1)heptanes useful as metal ion control agents and radioactive metal complexed therewith | |
GB1429549A (en) | Bone-seeking technetium-99m complex | |
WO1997012850A3 (de) | Bifunktionelle sulfidhaltige sulfonamid-chelatbildner vom typ xsny für radioaktive isotope |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19990201 |