DE69117741D1 - Neue vorangeordnete sechszähnige liganden verwendbar in röntgenologischen bildformenden wirkstoffen - Google Patents

Neue vorangeordnete sechszähnige liganden verwendbar in röntgenologischen bildformenden wirkstoffen

Info

Publication number
DE69117741D1
DE69117741D1 DE69117741T DE69117741T DE69117741D1 DE 69117741 D1 DE69117741 D1 DE 69117741D1 DE 69117741 T DE69117741 T DE 69117741T DE 69117741 T DE69117741 T DE 69117741T DE 69117741 D1 DE69117741 D1 DE 69117741D1
Authority
DE
Germany
Prior art keywords
sixteoth
generative
ray
new pre
ligands used
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69117741T
Other languages
English (en)
Other versions
DE69117741T2 (de
Inventor
Raghavan Rajagopalan
William Neumann
Dennis Nosco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Mallinckrodt Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Medical Inc filed Critical Mallinckrodt Medical Inc
Application granted granted Critical
Publication of DE69117741D1 publication Critical patent/DE69117741D1/de
Publication of DE69117741T2 publication Critical patent/DE69117741T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/14—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic the nitrogen atom of the amino group being further bound to hydrocarbon groups substituted by amino groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
DE69117741T 1990-12-14 1991-12-12 Neue vorangeordnete sechszähnige liganden verwendbar in röntgenologischen bildformenden wirkstoffen Expired - Fee Related DE69117741T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/627,175 US5908931A (en) 1990-12-14 1990-12-14 Preorganized hexadentate ligands useful in radiographic imaging agents
PCT/US1991/009334 WO1992010465A1 (en) 1990-12-14 1991-12-12 Novel preorganized hexadentate ligands useful in radiographic imaging agents

Publications (2)

Publication Number Publication Date
DE69117741D1 true DE69117741D1 (de) 1996-04-11
DE69117741T2 DE69117741T2 (de) 1996-07-18

Family

ID=24513532

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69117741T Expired - Fee Related DE69117741T2 (de) 1990-12-14 1991-12-12 Neue vorangeordnete sechszähnige liganden verwendbar in röntgenologischen bildformenden wirkstoffen

Country Status (8)

Country Link
US (2) US5908931A (de)
EP (1) EP0515638B1 (de)
JP (1) JPH05504777A (de)
AT (1) ATE134988T1 (de)
AU (1) AU646529B2 (de)
CA (1) CA2076024A1 (de)
DE (1) DE69117741T2 (de)
WO (1) WO1992010465A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69408145T2 (de) * 1993-07-19 1998-09-03 Resolution Pharm Inc Hydrazine mit einer n3s konfiguration als radionukleide chelatoren
US5858327A (en) * 1993-09-03 1999-01-12 Resolutions Pharmaceuticals, Inc. Hydrazino-type N2 S2 radionuclide chelating compounds
US5574140A (en) * 1993-09-03 1996-11-12 Resolution Pharmaceutical Inc. Hydrazino-type N2 S2 chelators
WO2000033841A1 (en) * 1998-12-07 2000-06-15 Smithkline Beecham Corporation Myt1 kinase inhibitors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB743683A (en) * 1953-05-20 1956-01-18 Dow Chemical Co Di-pyridyl aliphatic alkylene polyamine poly-acid compounds
US4481184A (en) * 1983-02-14 1984-11-06 E. R. Squibb & Sons, Inc. Cationic technetium (I) complexes
DE3324235A1 (de) * 1983-07-01 1985-01-10 Schering AG, 1000 Berlin und 4709 Bergkamen Neue komplexbildner, komplexe und komplexsalze
US4720586A (en) * 1983-12-06 1988-01-19 Fisons, Plc Substituted 3,4-dihydroxy-phenylethylamino compounds
EP0200211A1 (de) * 1985-05-01 1986-11-05 The Research Foundation Of State University Of New York Radiopharmazeutische Verbindungen zur Diagnose
US4842845A (en) * 1987-05-08 1989-06-27 Salutar, Inc. Radioactive metal chelates for dipyridoxyl phosphate
US4917879A (en) * 1989-05-19 1990-04-17 University Of Cincinnati 99MTC(III) myocardial imaging agents that are effective in humans
US5242681A (en) * 1990-03-12 1993-09-07 Research Corporation Technologies, Inc. Lipophilic contrast agents for diagnostic image analysis

Also Published As

Publication number Publication date
US5648060A (en) 1997-07-15
CA2076024A1 (en) 1992-06-15
US5908931A (en) 1999-06-01
DE69117741T2 (de) 1996-07-18
EP0515638A1 (de) 1992-12-02
ATE134988T1 (de) 1996-03-15
AU9101991A (en) 1992-07-08
AU646529B2 (en) 1994-02-24
WO1992010465A1 (en) 1992-06-25
JPH05504777A (ja) 1993-07-22
EP0515638B1 (de) 1996-03-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee