ES8700225A1 - Un procedimiento para preparar 1-((3,4-dimetoxifenetil)-ami-no)-3-(m-toliloxi)-2-propanol - Google Patents

Un procedimiento para preparar 1-((3,4-dimetoxifenetil)-ami-no)-3-(m-toliloxi)-2-propanol

Info

Publication number
ES8700225A1
ES8700225A1 ES542494A ES542494A ES8700225A1 ES 8700225 A1 ES8700225 A1 ES 8700225A1 ES 542494 A ES542494 A ES 542494A ES 542494 A ES542494 A ES 542494A ES 8700225 A1 ES8700225 A1 ES 8700225A1
Authority
ES
Spain
Prior art keywords
dimethoxyphenethyl
propanols
amino
preparation
substituted phenoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES542494A
Other languages
English (en)
Other versions
ES542494A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of ES8700225A1 publication Critical patent/ES8700225A1/es
Publication of ES542494A0 publication Critical patent/ES542494A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/04—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

PROCEDIMIENTO PARALA PREPARACION DE 1-(3,4-DIMETOXIFENIL)-AMINO-3-(M-TOLILOXI)-2-PROPANOL), BEVANTOLOL (I). CONSISTE EN LA REACCION DE LOS COMPUESTOS (II) Y (III) A UNA TEMPERATURA DE UNOS 20JC O INFERIOR, AÑADIENDO UN AGENTE DE SIEMBRA PARA FAVORECER LA CRISTALIZACION DEL PRODUCTO. EL BEVANTOLOL Y SUS DERIVADOS SON AGENTES FARMACOLOGICOS CON FUNCIONES DE BLOQUEO BETAADRENERGICO Y ACTIVIDAD CARDIOSELECTIVA.
ES542494A 1984-05-15 1985-04-23 Un procedimiento para preparar 1-((3,4-dimetoxifenetil)-ami-no)-3-(m-toliloxi)-2-propanol Expired ES8700225A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61053284A 1984-05-15 1984-05-15

Publications (2)

Publication Number Publication Date
ES8700225A1 true ES8700225A1 (es) 1986-09-16
ES542494A0 ES542494A0 (es) 1986-09-16

Family

ID=24445398

Family Applications (1)

Application Number Title Priority Date Filing Date
ES542494A Expired ES8700225A1 (es) 1984-05-15 1985-04-23 Un procedimiento para preparar 1-((3,4-dimetoxifenetil)-ami-no)-3-(m-toliloxi)-2-propanol

Country Status (18)

Country Link
US (1) US4994618A (es)
EP (1) EP0165682B1 (es)
JP (1) JPS60246351A (es)
KR (1) KR920007232B1 (es)
AR (1) AR241901A1 (es)
AT (1) ATE35410T1 (es)
AU (1) AU566985B2 (es)
CA (1) CA1225101A (es)
DE (1) DE3563532D1 (es)
DK (1) DK180285A (es)
ES (1) ES8700225A1 (es)
FI (1) FI851530L (es)
GR (1) GR851139B (es)
NO (1) NO160656C (es)
NZ (1) NZ211815A (es)
PH (1) PH20264A (es)
PT (1) PT80471B (es)
ZA (1) ZA852843B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1884251B (zh) * 2005-06-22 2010-06-23 北京德众万全医药科技有限公司 一种盐酸贝凡洛尔的精制方法
CN103936607A (zh) * 2013-01-23 2014-07-23 扬子江药业集团上海海尼药业有限公司 盐酸贝凡洛尔制备方法
CN104138360B (zh) * 2013-05-06 2016-03-02 扬子江药业集团上海海尼药业有限公司 盐酸贝凡洛尔片的制备方法
MA41557A (fr) 2015-02-18 2017-12-26 Auspex Pharmaceuticals Inc Inhibiteurs diméthoxyphényles du transporteur vésiculaire des monoamines 2

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3033640A (en) * 1954-06-16 1962-05-08 Saul & Co Incorporation of an organic basic compound into cellulose acetate materials
US2983757A (en) * 1959-02-18 1961-05-09 Abbott Lab Resolution of dl-methadone
NL301580A (es) * 1962-12-11
US3405159A (en) * 1964-11-17 1968-10-08 Merck & Co Inc Process for resolving racemic mixtures of optically-active enantiomorphs
US3978127A (en) * 1968-03-13 1976-08-31 Merck & Co., Inc. Tetrafluorophenethylaralkylamine compounds
BE790165A (fr) * 1971-12-14 1973-02-15 Parke Davis & Co Nouveaux aminoalcanols et procede pour les preparer
US3929856A (en) * 1971-12-14 1975-12-30 Parke Davis & Co 1-(3,4-Dimethoxyphenethylamino)-3-(phenoxy)-2-propanols
US4155935A (en) * 1973-03-26 1979-05-22 American Home Products Corporation Benzylamine analgesics
FR2330383A1 (fr) * 1975-11-06 1977-06-03 Synthelabo Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment
US4067904A (en) * 1975-12-19 1978-01-10 Mead Johnson & Company Alkylsulfonylphenoxypropanolamine derivatives

Also Published As

Publication number Publication date
NO160656C (no) 1989-05-16
DK180285D0 (da) 1985-04-22
AR241901A1 (es) 1993-01-29
JPS60246351A (ja) 1985-12-06
AU4134285A (en) 1985-11-21
NO851918L (no) 1985-11-18
PT80471A (en) 1985-06-01
AU566985B2 (en) 1987-11-05
CA1225101A (en) 1987-08-04
FI851530A0 (fi) 1985-04-17
EP0165682B1 (en) 1988-06-29
PT80471B (en) 1986-12-12
EP0165682A1 (en) 1985-12-27
PH20264A (en) 1986-11-14
US4994618A (en) 1991-02-19
KR850008658A (ko) 1985-12-21
NZ211815A (en) 1988-11-29
ATE35410T1 (de) 1988-07-15
NO160656B (no) 1989-02-06
DK180285A (da) 1985-11-16
KR920007232B1 (ko) 1992-08-28
DE3563532D1 (en) 1988-08-04
FI851530L (fi) 1985-11-16
ES542494A0 (es) 1986-09-16
GR851139B (es) 1985-11-25
ZA852843B (en) 1985-11-27

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506