ES8609328A1 - Un procedimiento para la preparacion de nuevos derivados de guanina. - Google Patents
Un procedimiento para la preparacion de nuevos derivados de guanina.Info
- Publication number
- ES8609328A1 ES8609328A1 ES547805A ES547805A ES8609328A1 ES 8609328 A1 ES8609328 A1 ES 8609328A1 ES 547805 A ES547805 A ES 547805A ES 547805 A ES547805 A ES 547805A ES 8609328 A1 ES8609328 A1 ES 8609328A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- hydrogen
- alkyl
- zero
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS DERIVADOS DE GUANINA COMO AGENTES AUTOINMUNES, DE FORMULA GENERAL (I), DONDE R3 ES HIDROGENO, HIDROXILO, MERCAPTO, BROMO O NHR SIENDO R HIDROGENO O COR6; R4 Y R5 SON HIDROGENO O UN RADICAL ALQUILO Y AR ES HETEROARILO. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON ACIDO FORMICO Y FORMAMIDA A ALTA TEMPERATURA. SE USAN EN EL TRATAMIENTO DE ENFERMEDADES AUTOINMUNES. EJERCEN UNA ACTIVIDAD INHIBIDORA DE ENZIMAS Y CITOTOXICA.-
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66015284A | 1984-10-12 | 1984-10-12 | |
US06/767,202 US4772606A (en) | 1985-08-22 | 1985-08-22 | Purine derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8609328A1 true ES8609328A1 (es) | 1986-09-01 |
ES547805A0 ES547805A0 (es) | 1986-09-01 |
Family
ID=27097992
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES547805A Expired ES8609328A1 (es) | 1984-10-12 | 1985-10-11 | Un procedimiento para la preparacion de nuevos derivados de guanina. |
ES553606A Expired ES8801273A1 (es) | 1984-10-12 | 1986-04-01 | Un procedimiento para la preparacion de nuevos derivados de purina |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES553606A Expired ES8801273A1 (es) | 1984-10-12 | 1986-04-01 | Un procedimiento para la preparacion de nuevos derivados de purina |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0178178A3 (es) |
KR (1) | KR860003255A (es) |
AU (1) | AU584126B2 (es) |
CA (1) | CA1260934A (es) |
DK (1) | DK458485A (es) |
ES (2) | ES8609328A1 (es) |
FI (1) | FI853891L (es) |
GR (1) | GR852468B (es) |
HU (1) | HU197747B (es) |
IL (1) | IL76546A (es) |
NO (1) | NO854050L (es) |
NZ (1) | NZ213798A (es) |
OA (1) | OA08120A (es) |
PH (1) | PH22811A (es) |
PT (1) | PT81293B (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ228645A (en) * | 1988-04-11 | 1991-09-25 | Iaf Biochem Int | 1,3-dioxolane derivatives substituted in the 5th position by a purine or pyrimidine radical; treatment of viral infections |
DK0460116T3 (da) * | 1989-02-27 | 1998-03-30 | Biocryst Pharm Inc | 9-substitueret-8-usubstitueret-9-deazaguaniner |
US4939252A (en) * | 1989-04-20 | 1990-07-03 | Hoffmann-La Roche Inc. | Novel intermediates for the preparation of Carbovir |
IL94390A (en) * | 1989-05-30 | 1996-03-31 | Merck & Co Inc | The 6-membered trans-nitrogen-containing heterocycles are compressed with imidazo and pharmaceutical preparations containing them |
US5272169A (en) * | 1992-03-27 | 1993-12-21 | The Dupont Merck Pharmaceutical Company | (N-benzyl) acetaldehyde bicyclic heterocycles useful as topical antiinflammatories |
US5217983A (en) * | 1992-03-27 | 1993-06-08 | Du Pont Merck Pharmaceutical Company | (N-benzyl) acetaldehyde bicyclic heterocycles useful as topical antiinflammatories |
HUT77436A (hu) * | 1994-10-05 | 1998-04-28 | Darwin Discovery Limited | Purin- és guaninszármazékok, eljárás előállításukra, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk gyógyszerkészítmények előállítására |
DE19501482A1 (de) * | 1995-01-19 | 1996-07-25 | Bayer Ag | 2,9-disubstituierte Purin-6-one |
GB9520363D0 (en) * | 1995-10-05 | 1995-12-06 | Chiroscience Ltd | Compounds |
GB9520364D0 (en) * | 1995-10-05 | 1995-12-06 | Chiroscience Ltd | Compouundds |
DE19541264A1 (de) * | 1995-11-06 | 1997-05-07 | Bayer Ag | Purin-6-on-derivate |
JP4397691B2 (ja) | 2001-10-30 | 2010-01-13 | コンフォーマ・セラピューティクス・コーポレイション | Hsp90阻害活性を有するプリン類似体 |
CN101906106A (zh) | 2003-09-18 | 2010-12-08 | 康福玛医药公司 | 作为hsp90-抑制剂的新的杂环化合物 |
CA2602257A1 (en) | 2005-03-30 | 2006-10-05 | Conforma Therapeutics Corporation | Alkynyl pyrrolopyrimidines and related analogs as hsp90-inhibitors |
US9221809B2 (en) | 2011-10-31 | 2015-12-29 | Merck Sharp & Dohme Corp. | Aminopyrimidinones as interleukin receptor-associated kinase inhibitors |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2844578A (en) * | 1955-09-14 | 1958-07-22 | Du Pont | Pyrimidine derivatives |
-
1985
- 1985-10-02 IL IL76546A patent/IL76546A/xx unknown
- 1985-10-04 AU AU48292/85A patent/AU584126B2/en not_active Ceased
- 1985-10-07 FI FI853891A patent/FI853891L/fi not_active Application Discontinuation
- 1985-10-08 DK DK458485A patent/DK458485A/da not_active Application Discontinuation
- 1985-10-10 CA CA000492727A patent/CA1260934A/en not_active Expired
- 1985-10-10 PH PH32916A patent/PH22811A/en unknown
- 1985-10-11 OA OA58702A patent/OA08120A/xx unknown
- 1985-10-11 PT PT81293A patent/PT81293B/pt not_active IP Right Cessation
- 1985-10-11 EP EP85307283A patent/EP0178178A3/en not_active Withdrawn
- 1985-10-11 NZ NZ213798A patent/NZ213798A/xx unknown
- 1985-10-11 ES ES547805A patent/ES8609328A1/es not_active Expired
- 1985-10-11 HU HU853956A patent/HU197747B/hu not_active IP Right Cessation
- 1985-10-11 NO NO854050A patent/NO854050L/no unknown
- 1985-10-11 GR GR852468A patent/GR852468B/el unknown
- 1985-10-12 KR KR1019850007507A patent/KR860003255A/ko not_active IP Right Cessation
-
1986
- 1986-04-01 ES ES553606A patent/ES8801273A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IL76546A (en) | 1988-12-30 |
DK458485A (da) | 1986-04-13 |
NZ213798A (en) | 1989-01-06 |
PT81293B (pt) | 1988-02-17 |
AU584126B2 (en) | 1989-05-18 |
HUT40131A (en) | 1986-11-28 |
AU4829285A (en) | 1986-04-17 |
PT81293A (en) | 1985-11-01 |
FI853891L (fi) | 1986-04-13 |
FI853891A0 (fi) | 1985-10-07 |
ES8801273A1 (es) | 1987-12-16 |
NO854050L (no) | 1986-04-14 |
HU197747B (en) | 1989-05-29 |
DK458485D0 (da) | 1985-10-08 |
CA1260934A (en) | 1989-09-26 |
EP0178178A3 (en) | 1987-08-12 |
GR852468B (es) | 1986-02-12 |
PH22811A (en) | 1988-12-27 |
ES547805A0 (es) | 1986-09-01 |
EP0178178A2 (en) | 1986-04-16 |
OA08120A (fr) | 1987-03-31 |
KR860003255A (ko) | 1986-05-21 |
ES553606A0 (es) | 1987-12-16 |
IL76546A0 (en) | 1986-02-28 |
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