ES8606341A1 - Un procedimiento para la preparacion de pirazolo piridinas. - Google Patents
Un procedimiento para la preparacion de pirazolo piridinas.Info
- Publication number
- ES8606341A1 ES8606341A1 ES540609A ES540609A ES8606341A1 ES 8606341 A1 ES8606341 A1 ES 8606341A1 ES 540609 A ES540609 A ES 540609A ES 540609 A ES540609 A ES 540609A ES 8606341 A1 ES8606341 A1 ES 8606341A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- hydrogen
- alkoxy
- pyrazolopyridine derivatives
- independently hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000005229 pyrazolopyridines Chemical class 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 125000006374 C2-C10 alkenyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- -1 polymethylene Polymers 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/16—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848404584A GB8404584D0 (en) | 1984-02-22 | 1984-02-22 | Compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8606341A1 true ES8606341A1 (es) | 1986-04-16 |
| ES540609A0 ES540609A0 (es) | 1986-04-16 |
Family
ID=10556988
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES540609A Expired ES8606341A1 (es) | 1984-02-22 | 1985-02-21 | Un procedimiento para la preparacion de pirazolo piridinas. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4670432A (OSRAM) |
| EP (1) | EP0152910B1 (OSRAM) |
| JP (1) | JPS60193987A (OSRAM) |
| AU (1) | AU581207B2 (OSRAM) |
| CA (1) | CA1242714A (OSRAM) |
| DE (1) | DE3571437D1 (OSRAM) |
| ES (1) | ES8606341A1 (OSRAM) |
| GB (1) | GB8404584D0 (OSRAM) |
| GR (1) | GR850441B (OSRAM) |
| NZ (1) | NZ211166A (OSRAM) |
| ZA (1) | ZA851281B (OSRAM) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT382377B (de) * | 1985-04-27 | 1987-02-25 | Beecham Group Plc | Verfahren zur herstellung von neuen 7-substituierten aminopyrazolo(4,3-b)pyridinen |
| EP0239191A3 (en) * | 1986-01-30 | 1988-07-20 | Beecham Group Plc | Pyrazolo[4,3-b]pyridine derivatives, process for their preparation and pharmaceutical compositions containing them |
| GB8609421D0 (en) * | 1986-04-17 | 1986-05-21 | Beecham Group Plc | Compounds |
| PE20020506A1 (es) * | 2000-08-22 | 2002-07-09 | Glaxo Group Ltd | Derivados de pirazol fusionados como inhibidores de la proteina cinasa |
| WO2002048148A2 (en) * | 2000-12-15 | 2002-06-20 | Glaxo Group Limited | Pyrazolopyridine derivatives |
| JP2004518651A (ja) | 2000-12-15 | 2004-06-24 | グラクソ グループ リミテッド | 治療用化合物 |
| EP1366048B1 (en) * | 2001-03-08 | 2004-08-25 | SmithKline Beecham Corporation | Pyrazolopyridine derivatives |
| WO2002078701A1 (en) * | 2001-03-30 | 2002-10-10 | Smithkline Beecham Corporation | Use of pyrazolopyridines as therapeutic compounds |
| WO2002078700A1 (en) * | 2001-03-30 | 2002-10-10 | Smithkline Beecham Corporation | Pyralopyridines, process for their preparation and use as therapteutic compounds |
| ATE332301T1 (de) * | 2001-04-10 | 2006-07-15 | Smithkline Beecham Corp | Antivirale pyrazolopyridin verbindungen |
| JP2004527560A (ja) * | 2001-04-27 | 2004-09-09 | スミスクライン ビーチャム コーポレーション | ピラゾロ［１，５−α］ピリジン誘導体 |
| IL158667A0 (en) * | 2001-06-21 | 2004-05-12 | Smithkline Beecham Corp | Imidazo [1,2-a] pyridine derivatives for the prophylaxis and treatment of herpes viral infections |
| ATE364043T1 (de) * | 2001-09-07 | 2007-06-15 | Smithkline Beecham Corp | Pyrazolo-pyridine für die behandlung von herpes- ansteckungen |
| WO2003031446A1 (en) * | 2001-10-05 | 2003-04-17 | Smithkline Beecham Corporation | Imidazo-pyridine derivatives for use in the treatment of herpes viral infection |
| EP1453830B1 (en) * | 2001-12-11 | 2007-09-12 | SmithKline Beecham Corporation | Pyrazolo-pyridine derivatives as antiherpes agents |
| JP2006504728A (ja) * | 2002-10-03 | 2006-02-09 | スミスクライン ビーチャム コーポレーション | ピラソロピリジン誘導体系治療用化合物 |
| US7459562B2 (en) | 2004-04-23 | 2008-12-02 | Bristol-Myers Squibb Company | Monocyclic heterocycles as kinase inhibitors |
| TW200538453A (en) | 2004-04-26 | 2005-12-01 | Bristol Myers Squibb Co | Bicyclic heterocycles as kinase inhibitors |
| US7439246B2 (en) | 2004-06-28 | 2008-10-21 | Bristol-Myers Squibb Company | Fused heterocyclic kinase inhibitors |
| US20050288290A1 (en) | 2004-06-28 | 2005-12-29 | Borzilleri Robert M | Fused heterocyclic kinase inhibitors |
| US7432373B2 (en) | 2004-06-28 | 2008-10-07 | Bristol-Meyers Squibb Company | Processes and intermediates useful for preparing fused heterocyclic kinase inhibitors |
| US7880004B2 (en) | 2005-09-15 | 2011-02-01 | Bristol-Myers Squibb Company | Met kinase inhibitors |
| US7547782B2 (en) | 2005-09-30 | 2009-06-16 | Bristol-Myers Squibb Company | Met kinase inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4048184A (en) * | 1976-11-15 | 1977-09-13 | E. R. Squibb & Sons, Inc. | 6-Phenyl-2H-pyrazolo[3,4-b]pyridines |
| EP0119774B1 (en) * | 1983-03-09 | 1987-06-24 | Beecham Group Plc | Anti-inflammatory pyrazolo pyridines |
| EP0151962A3 (en) * | 1984-01-25 | 1985-10-02 | Beecham Group Plc | Pyrazolopyridine derivatives |
| EP0193329A3 (en) * | 1985-02-22 | 1987-08-19 | Beecham Group Plc | Pyrazolopyridines, their preparation and pharmaceutical compositions containing them |
-
1984
- 1984-02-22 GB GB848404584A patent/GB8404584D0/en active Pending
-
1985
- 1985-02-13 EP EP85101566A patent/EP0152910B1/en not_active Expired
- 1985-02-13 DE DE8585101566T patent/DE3571437D1/de not_active Expired
- 1985-02-20 CA CA000474776A patent/CA1242714A/en not_active Expired
- 1985-02-20 NZ NZ211166A patent/NZ211166A/en unknown
- 1985-02-20 ZA ZA851281A patent/ZA851281B/xx unknown
- 1985-02-20 AU AU38972/85A patent/AU581207B2/en not_active Ceased
- 1985-02-20 GR GR850441A patent/GR850441B/el unknown
- 1985-02-21 ES ES540609A patent/ES8606341A1/es not_active Expired
- 1985-02-21 JP JP60031699A patent/JPS60193987A/ja active Pending
-
1986
- 1986-04-15 US US06/852,152 patent/US4670432A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU3897285A (en) | 1985-08-29 |
| CA1242714A (en) | 1988-10-04 |
| GR850441B (OSRAM) | 1985-06-19 |
| AU581207B2 (en) | 1989-02-16 |
| DE3571437D1 (de) | 1989-08-17 |
| ES540609A0 (es) | 1986-04-16 |
| ZA851281B (en) | 1985-11-27 |
| EP0152910B1 (en) | 1989-07-12 |
| JPS60193987A (ja) | 1985-10-02 |
| EP0152910A2 (en) | 1985-08-28 |
| NZ211166A (en) | 1988-01-08 |
| GB8404584D0 (en) | 1984-03-28 |
| EP0152910A3 (en) | 1986-07-16 |
| US4670432A (en) | 1987-06-02 |
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