ES8605811A1 - Un procedimiento para la preparacion de una b- lactama - Google Patents

Un procedimiento para la preparacion de una b- lactama

Info

Publication number
ES8605811A1
ES8605811A1 ES528985A ES528985A ES8605811A1 ES 8605811 A1 ES8605811 A1 ES 8605811A1 ES 528985 A ES528985 A ES 528985A ES 528985 A ES528985 A ES 528985A ES 8605811 A1 ES8605811 A1 ES 8605811A1
Authority
ES
Spain
Prior art keywords
beta
preparation
lactam compounds
image
lactam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES528985A
Other languages
English (en)
Other versions
ES528985A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838301688A external-priority patent/GB8301688D0/en
Priority claimed from GB838317199A external-priority patent/GB8317199D0/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES528985A0 publication Critical patent/ES528985A0/es
Publication of ES8605811A1 publication Critical patent/ES8605811A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D463/00Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/02Preparation
    • C07D463/06Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D505/00Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UNA B-LACTAMA. CONSISTE EN TRATAR UNA IMINA DE ESTRUCTURA PARCIAL (II) CON UN DERIVADO NUCLEOFILICO DE FORMAMIDA, COMO SON LOS DERIVADOS N-SILICICOS, N-ESTANNILICOS Y N-FOSFORILADOS O LOS DE FORMULA (III), EN UN DISOLVENTE ORGANICO, COMO DIOXANO, TETRAHIDROFURANO, DIMETILFORMAMIDA O HEXAMETILFOSFORAMIDA, EN ATMOSFERA INERTE Y A TEMPERATURA ENTRE C100 Y 30JC, PARA OBTENER UNA B-LACTAMA DE FORMULA (I). SIENDO: R1, ES UN GRUPO ACILO CARBOXILICO, SULFONILO O FOSFONILO; R Y R, IGUALES O DIFERENTES, UN GRUPO ALQUILO DE C 1 A 6, Y UNIDOS REPRESENTAN UN DI-RADICAL ALQUILENO DE C 2 A 4. SE UTILIZAN SUS COMPUESTOS SUSTITUIDOS COMO ANTIBACTERIANOS O INTERMEDIOS PARA LA INTRODUCCION DE LOS MISMOS.
ES528985A 1983-01-21 1984-01-19 Un procedimiento para la preparacion de una b- lactama Expired ES8605811A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838301688A GB8301688D0 (en) 1983-01-21 1983-01-21 Preparation of beta-lactam compounds
GB838317199A GB8317199D0 (en) 1983-06-24 1983-06-24 Preparation of beta-lactam compounds

Publications (2)

Publication Number Publication Date
ES528985A0 ES528985A0 (es) 1986-04-01
ES8605811A1 true ES8605811A1 (es) 1986-04-01

Family

ID=26284987

Family Applications (1)

Application Number Title Priority Date Filing Date
ES528985A Expired ES8605811A1 (es) 1983-01-21 1984-01-19 Un procedimiento para la preparacion de una b- lactama

Country Status (19)

Country Link
US (1) US4555363A (es)
EP (1) EP0115405B1 (es)
KR (1) KR910005846B1 (es)
AU (1) AU568530B2 (es)
CA (1) CA1222745A (es)
DE (1) DE3464135D1 (es)
DK (1) DK23784A (es)
ES (1) ES8605811A1 (es)
FI (1) FI81354C (es)
GR (1) GR79174B (es)
HU (1) HU191584B (es)
IE (1) IE56571B1 (es)
IL (1) IL70721A (es)
NO (1) NO164031C (es)
NZ (1) NZ206892A (es)
PH (1) PH21570A (es)
PL (1) PL146761B1 (es)
PT (1) PT77980B (es)
YU (1) YU43662B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0150378B1 (en) * 1984-01-23 1990-03-28 Takeda Chemical Industries, Ltd. Cephem compounds and their production
GB8416648D0 (en) * 1984-06-29 1984-08-01 Beecham Group Plc Chemical process
EP0211656A3 (en) * 1985-08-10 1988-03-09 Beecham Group Plc Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them
EP0389176A3 (en) * 1989-03-18 1992-01-15 Beecham Group p.l.c. Beta-lactams and processes for their preparation
ATE118215T1 (de) * 1989-09-04 1995-02-15 Beecham Group Plc Cephalosporinderivate, verfahren zu ihrer herstellung, pharmazeutische präparate und zwischenverbindungen.
WO2021099842A1 (en) * 2019-11-22 2021-05-27 2692372 Ontario Inc. Pentafluorobenzenesulfonamide derivatives and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2647815A (en) * 1951-05-03 1953-08-04 Gen Aniline & Film Corp Alkyl diformyl phenylenediamines
GB2107307B (en) * 1981-07-25 1986-02-26 Beecham Group Plc B-lactum antibacterial agents

Also Published As

Publication number Publication date
PL245815A1 (en) 1985-07-02
KR840007411A (ko) 1984-12-07
NO164031B (no) 1990-05-14
CA1222745A (en) 1987-06-09
ES528985A0 (es) 1986-04-01
PT77980A (en) 1984-02-01
DE3464135D1 (en) 1987-07-16
EP0115405A2 (en) 1984-08-08
DK23784D0 (da) 1984-01-19
AU2360884A (en) 1984-07-26
IL70721A0 (en) 1984-04-30
GR79174B (es) 1984-10-02
HUT34207A (en) 1985-02-28
AU568530B2 (en) 1988-01-07
FI840215A0 (fi) 1984-01-19
DK23784A (da) 1984-07-22
IL70721A (en) 1989-02-28
EP0115405B1 (en) 1987-06-10
NZ206892A (en) 1987-02-20
PH21570A (en) 1987-12-11
PT77980B (en) 1986-03-25
NO164031C (no) 1990-08-22
NO840211L (no) 1984-07-23
EP0115405A3 (en) 1984-08-29
FI81354C (fi) 1990-10-10
YU43662B (en) 1989-10-31
PL146761B1 (en) 1989-03-31
IE56571B1 (en) 1991-09-11
KR910005846B1 (ko) 1991-08-05
YU10284A (en) 1987-02-28
FI81354B (fi) 1990-06-29
FI840215A (fi) 1984-07-22
HU191584B (en) 1987-03-30
IE840111L (en) 1984-07-21
US4555363A (en) 1985-11-26

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960401