ES8604562A1 - Un procedimiento para la preparacion de nuevos derivados de quinazolina e isoquinolina - Google Patents
Un procedimiento para la preparacion de nuevos derivados de quinazolina e isoquinolinaInfo
- Publication number
- ES8604562A1 ES8604562A1 ES545936A ES545936A ES8604562A1 ES 8604562 A1 ES8604562 A1 ES 8604562A1 ES 545936 A ES545936 A ES 545936A ES 545936 A ES545936 A ES 545936A ES 8604562 A1 ES8604562 A1 ES 8604562A1
- Authority
- ES
- Spain
- Prior art keywords
- quinazoline
- substd
- opt
- pyridyl
- isoquinoline derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE QUINAZOLINA E ISOQUINOLINA, DE FORMULA GENERAL (I), EN LA QUE X REPRESENTA NITROGENO O UN GRUPO -CH-; R1 Y R2 REPRESENTAN HIDROGENO, ALQUILO O ALCOXI; R3 REPRESENTA UN GRUPO 2-PIRIDILO SUSTITUIDO ONO SUSTITUIDO; Y R4 REPRESENTA HIDROGENO, UN GRUPO ALQUILO, ALCOXI O FENILO, Y SUS SALES DE ADICION DE ACIDO Y SUS COMPLEJOS DE COBRE. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE R1, R2, R3 Y X TIENEN LOS SIGNIFICADOS YA MENCIONADOS, CON UN NITRILO DE FORMULA GENERAL (III), EN LA QUE R4 TIENE EL SIGNIFICADO INDICADO. DE APLICACION EN TERAPEUTICA POR SU ACCION BIOCIDA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL8303328 | 1983-09-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8604562A1 true ES8604562A1 (es) | 1986-02-01 |
ES545936A0 ES545936A0 (es) | 1986-02-01 |
Family
ID=19842465
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES536402A Granted ES536402A0 (es) | 1983-09-29 | 1984-09-28 | Un procedimiento para la preparacion de nuevos derivados de quinazolina e isoquinolina. |
ES545936A Expired ES8604562A1 (es) | 1983-09-29 | 1985-08-06 | Un procedimiento para la preparacion de nuevos derivados de quinazolina e isoquinolina |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES536402A Granted ES536402A0 (es) | 1983-09-29 | 1984-09-28 | Un procedimiento para la preparacion de nuevos derivados de quinazolina e isoquinolina. |
Country Status (11)
Country | Link |
---|---|
US (1) | US4694000A (es) |
EP (1) | EP0135975B1 (es) |
JP (1) | JPS61500019A (es) |
AT (1) | ATE37183T1 (es) |
AU (1) | AU572585B2 (es) |
CA (1) | CA1255674A (es) |
DE (1) | DE3474022D1 (es) |
ES (2) | ES536402A0 (es) |
NZ (1) | NZ209710A (es) |
WO (1) | WO1985001501A1 (es) |
ZA (1) | ZA847673B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2582514B1 (fr) * | 1985-05-30 | 1988-02-19 | Rhone Poulenc Sante | Medicaments a base d'amides, nouveaux amides et leur preparation |
DE3675197D1 (de) * | 1985-12-03 | 1990-11-29 | Sumitomo Chemical Co | Pyridinylpyrimidin-derivate, verfahren zu deren herstellung und diese als wirksamen stoff enthaltende pflanzenkrankheiten-schutzmittel. |
IL91664A (en) * | 1988-09-28 | 1993-05-13 | Yissum Res Dev Co | Ammonium transmembrane gradient system for efficient loading of liposomes with amphipathic drugs and their controlled release |
JP2657760B2 (ja) * | 1992-07-15 | 1997-09-24 | 小野薬品工業株式会社 | 4−アミノキナゾリン誘導体およびそれを含有する医薬品 |
US5583211A (en) * | 1992-10-29 | 1996-12-10 | Beckman Instruments, Inc. | Surface activated organic polymers useful for location - specific attachment of nucleic acids, peptides, proteins and oligosaccharides |
US5939431A (en) * | 1996-06-20 | 1999-08-17 | Schering Corporation | Naphthyridines which affect IL-4 and G-CSF |
US5929085A (en) * | 1996-11-06 | 1999-07-27 | Astra Aktiebolag | Amidine and isothiourea derivatives, compositions containing them and their use as inhibitors of nitric oxide synthase |
US6124374A (en) * | 1998-05-29 | 2000-09-26 | Block Drug Company, Inc. | Antimicrobial denture adhesive and cleanser compositions |
ITTO20040125A1 (it) * | 2004-03-01 | 2004-06-01 | Rotta Research Lab | Nuove amidine eterocicliche inibitrici la produzione di ossido d'azoto (no) ad attivita' antinfiammatoria ed analgesica |
CA2555867A1 (en) * | 2004-03-04 | 2005-09-22 | Neurogen Corporation | Arylalkylamino-substituted quinazoline analogues |
JP2009519995A (ja) * | 2005-12-20 | 2009-05-21 | ノイロサーチ アクティーゼルスカブ | 呼吸器疾患の治療のためのカリウムチャンネル調節剤としての2−ピリジン−2−イル−キナゾリン誘導体 |
NL1035408C2 (nl) * | 2008-05-13 | 2009-11-16 | Dafra Pharma N V | Tuberculose prodrug derivaten. |
CA2780111A1 (en) | 2009-11-07 | 2011-05-12 | Merck Patent Gmbh | Heteroarylaminoquinolines as tgf-beta receptor kinase inhibitors |
CN105175347B (zh) * | 2015-09-25 | 2018-01-23 | 温州医科大学附属第二医院 | 一种含氮杂环药物中间体的合成方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3674791A (en) * | 1968-03-26 | 1972-07-04 | Marion Laboratories Inc | Benzamido 2 lower alkyl decahydroisoquinolines |
GB1390015A (en) * | 1971-05-07 | 1975-04-09 | Koninklijke Pharma Fab Nv | 4-amino-quinazoline compounds |
BE788608A (fr) * | 1971-09-09 | 1973-03-08 | Koninklijke Pharma Fab Nv | Aminoisoquinoleines |
US4125724A (en) * | 1975-12-29 | 1978-11-14 | Bristol-Myers Company | Hydrogenation process |
GB2002746A (en) * | 1977-06-17 | 1979-02-28 | Gist Brocades Nv | Copper complexes |
US4171581A (en) * | 1977-11-14 | 1979-10-23 | Deepsea Ventures, Inc. | Water flow-deflecting shield for dredge suction nozzle |
DE2818403A1 (de) * | 1978-04-27 | 1979-11-08 | Hoechst Ag | Neue isochinolinderivate und verfahren zu ihrer herstellung |
-
1984
- 1984-09-28 EP EP84201386A patent/EP0135975B1/en not_active Expired
- 1984-09-28 JP JP59503906A patent/JPS61500019A/ja active Pending
- 1984-09-28 WO PCT/EP1984/000312 patent/WO1985001501A1/en unknown
- 1984-09-28 DE DE8484201386T patent/DE3474022D1/de not_active Expired
- 1984-09-28 ZA ZA847673A patent/ZA847673B/xx unknown
- 1984-09-28 AT AT84201386T patent/ATE37183T1/de not_active IP Right Cessation
- 1984-09-28 CA CA000464249A patent/CA1255674A/en not_active Expired
- 1984-09-28 AU AU35518/84A patent/AU572585B2/en not_active Ceased
- 1984-09-28 US US06/679,000 patent/US4694000A/en not_active Expired - Fee Related
- 1984-09-28 ES ES536402A patent/ES536402A0/es active Granted
- 1984-09-28 NZ NZ209710A patent/NZ209710A/en unknown
-
1985
- 1985-08-06 ES ES545936A patent/ES8604562A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0135975A2 (en) | 1985-04-03 |
AU572585B2 (en) | 1988-05-12 |
DE3474022D1 (de) | 1988-10-20 |
ES545936A0 (es) | 1986-02-01 |
WO1985001501A1 (en) | 1985-04-11 |
EP0135975A3 (en) | 1985-06-12 |
ES8603459A1 (es) | 1985-12-16 |
US4694000A (en) | 1987-09-15 |
ES536402A0 (es) | 1985-12-16 |
JPS61500019A (ja) | 1986-01-09 |
EP0135975B1 (en) | 1988-09-14 |
AU3551884A (en) | 1985-04-23 |
CA1255674A (en) | 1989-06-13 |
NZ209710A (en) | 1988-02-12 |
ATE37183T1 (de) | 1988-09-15 |
ZA847673B (en) | 1985-05-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8604562A1 (es) | Un procedimiento para la preparacion de nuevos derivados de quinazolina e isoquinolina | |
ES411804A1 (es) | Procedimiento para la obtencion de derivados de quinoxalinay quinazolina. | |
DE69532817D1 (de) | Verwendung von pyrazole verbindungen zur behandlung von glomerulonephritis, krebs, atherosklerose oder restenose | |
ATE49763T1 (de) | 1h-imidazo(4,5c)chinoline und 1h-imidazo(4,5c)chinolin-4-amine. | |
ES8601878A1 (es) | Procedimiento para preparar nuevas 1-bencil-aminoalquil-pi- rrolidinonas | |
HU902023D0 (en) | Process for producing new quinoline derivatives and antibacterial preparatives containing these compounds as active substance | |
KR890000467A (ko) | 피리딘 유도체 및 그것을 함유하는 궤양 치료제 | |
ES8501771A1 (es) | Procedimiento para la preparacion de un nuevo compuesto heterociclico | |
IL68228A0 (en) | Thiomethylpyridine derivatives,process for the production thereof and medicaments containing them | |
DE3876312D1 (de) | (azolyl-vinyl)-phenol-alkenylether. | |
GB1260352A (en) | New derivatives of benzoxazolin-2-one and methods for producing the same | |
ATE35539T1 (de) | Verbindungen mit fungizider wirkung. | |
ES8604121A1 (es) | Procedimiento para la preparacion de esteres de acido guani-dinobenzoico | |
FR2529891B1 (es) | ||
GB1353508A (en) | Aminoisoquinolines | |
ES332749A1 (es) | Procedimiento para la produccion de derivados de la sulfo- nil urea. | |
GB1158632A (en) | New Tri- and Tetrathiophosphate Esters | |
ES8607209A1 (es) | Procedimiento para la obtencion de derivados de aminofenile-tilamina monosililados | |
ES8603903A1 (es) | Un procedimiento para preparar monosales y disales de fosfo-nicina con imidazol y-o sus derivados | |
ES8601147A1 (es) | Procedimiento de preparacion de aminoetilimidazol | |
GB1488851A (en) | 2-amino-tetralin-1-ones | |
ES324155A1 (es) | Un procedimiento para la preparacion de penicilinas. | |
HUT34679A (en) | Fungicide preparations containing phosphorilized azolyl-derivatives as agent and process for the production of the agent | |
ES351343A1 (es) | Un procedimiento para la preparacion de derivados de benzo-diacepina. | |
ES387878A1 (es) | Un procedimiento para derivados de benzodiazepina y sales de los mismos. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Patent lapsed |
Effective date: 19960401 |