ES8603459A1 - Un procedimiento para la preparacion de nuevos derivados de quinazolina e isoquinolina. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de quinazolina e isoquinolina.

Info

Publication number
ES8603459A1
ES8603459A1 ES536402A ES536402A ES8603459A1 ES 8603459 A1 ES8603459 A1 ES 8603459A1 ES 536402 A ES536402 A ES 536402A ES 536402 A ES536402 A ES 536402A ES 8603459 A1 ES8603459 A1 ES 8603459A1
Authority
ES
Spain
Prior art keywords
quinazoline
substd
opt
pyridyl
isoquinoline derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES536402A
Other languages
English (en)
Other versions
ES536402A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Publication of ES536402A0 publication Critical patent/ES536402A0/es
Publication of ES8603459A1 publication Critical patent/ES8603459A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE QUINAZOLINA E ISOQUINOLINA, DE FORMULA GENERAL (I), EN LA QUE X ES NITROGENO O UN GRUPO -CH-; R1 Y R2 REPRESENTAN HIDROGENO, ALQUILO O ALCOXI; R3 REPRESENTA UN GRUPO 2-PIRIDILO SUSTITUIDO O NO SUSTITUIDO; Y R4 REPRESENTA HIDROGENO O UN GRUPO ALQUILO, Y SUS SALES DE ADICION DE ACIDO Y SUS COMPLEJOS DE COBRE. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE R1, R2, R3 Y R4 TIENEN LOS SIGNIFICADOS YA MENCIONADOS; Y Z REPRESENTA HALOGENO O UN GRUPO ALCOXI C1-4. DE APLICACION EN FARMACIA Y MEDICINA POR SU ACCION BIOCIDA, EN ESPECIAL CONTRA LAS BACTERIAS GRAM-POSITIVAS, PROTOZOOS Y SOBRE TODO CONTRA LOS MICROORGANISMOS DEL TIPO DE PLEUROPNEUMONIA.
ES536402A 1983-09-29 1984-09-28 Un procedimiento para la preparacion de nuevos derivados de quinazolina e isoquinolina. Expired ES8603459A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8303328 1983-09-29

Publications (2)

Publication Number Publication Date
ES536402A0 ES536402A0 (es) 1985-12-16
ES8603459A1 true ES8603459A1 (es) 1985-12-16

Family

ID=19842465

Family Applications (2)

Application Number Title Priority Date Filing Date
ES536402A Expired ES8603459A1 (es) 1983-09-29 1984-09-28 Un procedimiento para la preparacion de nuevos derivados de quinazolina e isoquinolina.
ES545936A Expired ES8604562A1 (es) 1983-09-29 1985-08-06 Un procedimiento para la preparacion de nuevos derivados de quinazolina e isoquinolina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES545936A Expired ES8604562A1 (es) 1983-09-29 1985-08-06 Un procedimiento para la preparacion de nuevos derivados de quinazolina e isoquinolina

Country Status (11)

Country Link
US (1) US4694000A (es)
EP (1) EP0135975B1 (es)
JP (1) JPS61500019A (es)
AT (1) ATE37183T1 (es)
AU (1) AU572585B2 (es)
CA (1) CA1255674A (es)
DE (1) DE3474022D1 (es)
ES (2) ES8603459A1 (es)
NZ (1) NZ209710A (es)
WO (1) WO1985001501A1 (es)
ZA (1) ZA847673B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2582514B1 (fr) * 1985-05-30 1988-02-19 Rhone Poulenc Sante Medicaments a base d'amides, nouveaux amides et leur preparation
DE3675197D1 (de) * 1985-12-03 1990-11-29 Sumitomo Chemical Co Pyridinylpyrimidin-derivate, verfahren zu deren herstellung und diese als wirksamen stoff enthaltende pflanzenkrankheiten-schutzmittel.
IL91664A (en) * 1988-09-28 1993-05-13 Yissum Res Dev Co Ammonium transmembrane gradient system for efficient loading of liposomes with amphipathic drugs and their controlled release
JP2657760B2 (ja) * 1992-07-15 1997-09-24 小野薬品工業株式会社 ４−アミノキナゾリン誘導体およびそれを含有する医薬品
US5583211A (en) * 1992-10-29 1996-12-10 Beckman Instruments, Inc. Surface activated organic polymers useful for location - specific attachment of nucleic acids, peptides, proteins and oligosaccharides
US5939431A (en) * 1996-06-20 1999-08-17 Schering Corporation Naphthyridines which affect IL-4 and G-CSF
US5929085A (en) * 1996-11-06 1999-07-27 Astra Aktiebolag Amidine and isothiourea derivatives, compositions containing them and their use as inhibitors of nitric oxide synthase
US6124374A (en) * 1998-05-29 2000-09-26 Block Drug Company, Inc. Antimicrobial denture adhesive and cleanser compositions
ITTO20040125A1 (it) * 2004-03-01 2004-06-01 Rotta Research Lab Nuove amidine eterocicliche inibitrici la produzione di ossido d'azoto (no) ad attivita' antinfiammatoria ed analgesica
EP1720542A4 (en) * 2004-03-04 2007-11-28 Neurogen Corp ARYL ALKYLAMINO-SUBSTITUTED CHINAZOLINE ANALOGUE
JP2009519995A (ja) * 2005-12-20 2009-05-21 ノイロサーチ アクティーゼルスカブ 呼吸器疾患の治療のためのカリウムチャンネル調節剤としての２−ピリジン−２−イル−キナゾリン誘導体
NL1035408C2 (nl) * 2008-05-13 2009-11-16 Dafra Pharma N V Tuberculose prodrug derivaten.
US8987301B2 (en) 2009-11-07 2015-03-24 Merck Patent Gmbh Heteroarylaminoquinolines as TGF-beta receptor kinase inhibitors
CN105175347B (zh) * 2015-09-25 2018-01-23 温州医科大学附属第二医院 一种含氮杂环药物中间体的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3674791A (en) * 1968-03-26 1972-07-04 Marion Laboratories Inc Benzamido 2 lower alkyl decahydroisoquinolines
GB1390014A (en) * 1971-05-07 1975-04-09 Koninklijke Pharma Fab Nv Process for the preparation of carbocyclic fused pyrimidine derivatives
BE788608A (fr) * 1971-09-09 1973-03-08 Koninklijke Pharma Fab Nv Aminoisoquinoleines
US4125724A (en) * 1975-12-29 1978-11-14 Bristol-Myers Company Hydrogenation process
DE2826526A1 (de) * 1977-06-17 1979-01-04 Gist Brocades Nv Kupferkomplexe von phenanthrolin-, isochinolin- und chinazolinderivaten, verfahren zu ihrer herstellung und ihre verwendung bei der bekaempfung von mykoplasmainfektionen
US4171581A (en) * 1977-11-14 1979-10-23 Deepsea Ventures, Inc. Water flow-deflecting shield for dredge suction nozzle
DE2818403A1 (de) * 1978-04-27 1979-11-08 Hoechst Ag Neue isochinolinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
EP0135975A2 (en) 1985-04-03
US4694000A (en) 1987-09-15
ES536402A0 (es) 1985-12-16
ES545936A0 (es) 1986-02-01
NZ209710A (en) 1988-02-12
ZA847673B (en) 1985-05-29
DE3474022D1 (de) 1988-10-20
WO1985001501A1 (en) 1985-04-11
EP0135975B1 (en) 1988-09-14
JPS61500019A (ja) 1986-01-09
AU572585B2 (en) 1988-05-12
ES8604562A1 (es) 1986-02-01
ATE37183T1 (de) 1988-09-15
AU3551884A (en) 1985-04-23
EP0135975A3 (en) 1985-06-12
CA1255674A (en) 1989-06-13

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960401