ES8601855A1 - Procedimiento para producir una n-acilfenilalanina - Google Patents

Procedimiento para producir una n-acilfenilalanina

Info

Publication number
ES8601855A1
ES8601855A1 ES542019A ES542019A ES8601855A1 ES 8601855 A1 ES8601855 A1 ES 8601855A1 ES 542019 A ES542019 A ES 542019A ES 542019 A ES542019 A ES 542019A ES 8601855 A1 ES8601855 A1 ES 8601855A1
Authority
ES
Spain
Prior art keywords
acylphenylalanines
producing
methylenedioxy
aryloxy
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES542019A
Other languages
English (en)
Other versions
ES542019A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Publication of ES542019A0 publication Critical patent/ES542019A0/es
Publication of ES8601855A1 publication Critical patent/ES8601855A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/10—Preparation of carboxylic acid amides from compounds not provided for in groups C07C231/02 - C07C231/08
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)

Abstract

PROCEDIMIENTO PARA PRODUCIR UNA N-ACIFENILALANINA. CONSISTE EN HIDROLIZAR CON UN HIDROXIDO, OXIDO O CARBONATO DE UN ALCALI O METAL ALCALINOTERREO UN COMPUESTO DE FORMULA (I) DONDE R1 Y R2 SON HIDROGENO, ALQUILO DE 1-4 CARBONOS, ALCOXI DE 1-4 CARBONOS, HALOGENO U OTROS VARIOS Y R3 ES METILO O FENILO, DURANTE 1-15 HORAS A TEMPERATURA DE 20 A 80 C PARA PRODUCIR UN ACIDO A-ACILAMINOCINAMICO, EL CUAL, POR REDUCCION CATALITICA EN PRESENCIA DE UN CATALIZADOR DE PALADIO O DE PLATINO A PH ENTRE 5,5 Y 8,5 DARA LUGAR AL COMPUESTO (II) DESDE R4 Y R5 SON HIDROGENO, ALQUILO DE 1-4 CARBONOS, ALCOXI DE 1-4 CARBONOS, HALOGENO U OTROS VARIOS. DE APLICACION COMO PRECURSORES DE FENILALANINA.
ES542019A 1984-04-10 1985-04-08 Procedimiento para producir una n-acilfenilalanina Expired ES8601855A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59069999A JPS60215657A (ja) 1984-04-10 1984-04-10 Ｎ−アシルフエニルアラニン類の製造法

Publications (2)

Publication Number Publication Date
ES542019A0 ES542019A0 (es) 1985-12-01
ES8601855A1 true ES8601855A1 (es) 1985-12-01

Family

ID=13418875

Family Applications (1)

Application Number Title Priority Date Filing Date
ES542019A Expired ES8601855A1 (es) 1984-04-10 1985-04-08 Procedimiento para producir una n-acilfenilalanina

Country Status (9)

Country Link
US (1) US4612388A (es)
EP (1) EP0161796B1 (es)
JP (1) JPS60215657A (es)
KR (1) KR870000368B1 (es)
AU (1) AU558388B2 (es)
CA (1) CA1228364A (es)
DE (1) DE3568573D1 (es)
ES (1) ES8601855A1 (es)
MX (1) MX162421A (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU194485B (en) * 1985-12-06 1988-02-29 Budapesti Vegyimuevek Herbicides and fungicides containing as active substance derivatives of new phenoxi-benziliden-oxazolinon and process for production of the active substances
AU605132B2 (en) * 1986-01-03 1991-01-10 Consolidated Pharmaceuticals Limited Melphalan derivatives
JPS62205095A (ja) * 1986-03-04 1987-09-09 Toyo Jozo Co Ltd 新生理活性物質アルドスタチンおよびその製造法
DE3736861A1 (de) * 1987-10-30 1989-05-11 Hoechst Ag Verfahren zur herstellung von n-acetylphenylalanin
IT1226903B (it) * 1988-07-12 1991-02-21 Mini Ricerca Scient Tecnolog Processo per la sintesi di aminoacidi otticamente attivi
CA2139350A1 (en) * 1992-06-30 1994-01-06 Joseph C. Hogan, Jr. Oxazolone derived materials
WO1995018627A1 (en) * 1994-01-05 1995-07-13 Arqule, Inc. Method of making polymers having specific properties
TW200624151A (en) * 2004-11-12 2006-07-16 Monsanto Technology Llc Recovery of noble metals from aqueous process streams
CN101684077B (zh) 2008-09-24 2013-01-02 浙江九洲药业股份有限公司 N-酰基联苯丙氨酸的制备方法
CA2772681C (en) * 2009-09-23 2017-01-03 Zhejiang Jiuzhou Pharmaceutical Co., Ltd. Process for manufacture of n-acylbphenyl alanine
CN111518049B (zh) * 2019-02-01 2024-05-03 鲁南制药集团股份有限公司 Magl抑制剂、制备方法及用途
CN111518048B (zh) * 2019-02-01 2024-04-30 鲁南制药集团股份有限公司 Magl抑制剂、制备方法和用途
CN111518047B (zh) * 2019-02-01 2024-05-24 鲁南制药集团股份有限公司 Magl抑制剂及制备方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2678313A (en) * 1954-05-11 Stable molecular compounds of
US3085111A (en) * 1957-03-19 1963-04-09 Warner Lambert Pharmaceutical Process for preparing 3-nitrobenzaldehyde ethers
CH441362A (de) * 1963-12-24 1967-08-15 Hoffmann La Roche Verfahren zur Herstellung von Phenylalaninderivaten
US3544623A (en) * 1966-05-18 1970-12-01 Warner Lambert Pharmaceutical 3-isopropyltyrosine
US4261919A (en) * 1968-09-09 1981-04-14 Monsanto Company Catalytic asymmetric hydrogenation
AT313224B (de) * 1970-01-19 1974-01-15 Astra Laekemedel Ab Verfahren zur herstellung von l(-)-3-(3,4-dihydroxyphenyl)-alanin undl (-)-3-(3-hydroxyphenyl)-alanin und den entsprechenden veraetherten derivaten
US4508921A (en) * 1984-06-28 1985-04-02 Merck & Co., Inc. Process for preparation of alpha-alkyl amino acids

Also Published As

Publication number Publication date
DE3568573D1 (en) 1989-04-13
EP0161796A1 (en) 1985-11-21
KR870000368B1 (ko) 1987-03-06
MX162421A (es) 1991-05-09
ES542019A0 (es) 1985-12-01
JPS60215657A (ja) 1985-10-29
US4612388A (en) 1986-09-16
KR850007795A (ko) 1985-12-09
JPH0542422B2 (es) 1993-06-28
EP0161796B1 (en) 1989-03-08
CA1228364A (en) 1987-10-20
AU558388B2 (en) 1987-01-29
AU4078785A (en) 1985-10-17

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001