ES8507132A1 - Proceso para producir un derivado de tetrahidronaftilcarboxilato de fenilo - Google Patents

Proceso para producir un derivado de tetrahidronaftilcarboxilato de fenilo

Info

Publication number
ES8507132A1
ES8507132A1 ES532778A ES532778A ES8507132A1 ES 8507132 A1 ES8507132 A1 ES 8507132A1 ES 532778 A ES532778 A ES 532778A ES 532778 A ES532778 A ES 532778A ES 8507132 A1 ES8507132 A1 ES 8507132A1
Authority
ES
Spain
Prior art keywords
group
tetrahydronaphthylcarboxylate
phenyl
lower alkylene
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES532778A
Other languages
English (en)
Other versions
ES532778A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
Original Assignee
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Publication of ES8507132A1 publication Critical patent/ES8507132A1/es
Publication of ES532778A0 publication Critical patent/ES532778A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE DERIVADOS DEL TETRAHIDRONAFTILCARBOXILATO DE FENILO, DE FORMULA (I) EN LA QUE A ES UN ENLACE DIRECTO O UN GRUPO ALQUILENO, VINILENO O IMINIO INFERIOR; B ES UN ENLACE DIRECTO, UN GRUPO ALQUILENO INFERIOR OALQUILENO INFERIOR-NH-, O UN GRUPO RESIDUAL -OCH2CO; Y R ES UN GRUPO ALQUILO INFERIOR.MEDIANTE REACCION DE UN ACIDO TETRAHIDRONAFTILCARBOXILICO, DE FORMULA (II), CON UN FENOL SUSTITUIDO 4, DE FORMULA (III), EN LA QUE A, B Y R SON LOS YA INDICADOS. LA REACCION PUEDE DESARROLLARSE EN PRESENCIA DE UN AGENTE DESHIDRATANTE COMO LA DICLOHEXILCARBODIMIDA O SIMILAR.DE APLICACION POR SU EFECTO INHIBIDOR SOBRE LA QUIMOTRIPSINA.
ES532778A 1983-06-02 1984-05-24 Proceso para producir un derivado de tetrahidronaftilcarboxilato de fenilo Granted ES532778A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58098713A JPS59222484A (ja) 1983-06-02 1983-06-02 テトラヒドロナフチルカルボン酸フエニルエステル誘導体

Publications (2)

Publication Number Publication Date
ES8507132A1 true ES8507132A1 (es) 1985-09-01
ES532778A0 ES532778A0 (es) 1985-09-01

Family

ID=14227151

Family Applications (1)

Application Number Title Priority Date Filing Date
ES532778A Granted ES532778A0 (es) 1983-06-02 1984-05-24 Proceso para producir un derivado de tetrahidronaftilcarboxilato de fenilo

Country Status (5)

Country Link
US (1) US4620005A (es)
EP (1) EP0128007A3 (es)
JP (1) JPS59222484A (es)
CA (1) CA1233467A (es)
ES (1) ES532778A0 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9902987D0 (sv) 1999-08-24 1999-08-24 Astra Pharma Prod Novel compounds
CO5300399A1 (es) 2000-02-25 2003-07-31 Astrazeneca Ab Heterocicliocs que contienen nitrogeno, proceso para su preparacion y composiciones farmaceuticas que los contienen
US7005439B2 (en) 2000-06-20 2006-02-28 Astrazeneca Ab Compounds
AR028948A1 (es) 2000-06-20 2003-05-28 Astrazeneca Ab Compuestos novedosos
GB0104050D0 (en) 2001-02-19 2001-04-04 Astrazeneca Ab Chemical compounds
AR035230A1 (es) 2001-03-19 2004-05-05 Astrazeneca Ab Compuestos de bencimidazol, proceso para su preparacion, composicion farmaceutica, proceso para la preparacion de dicha composicion farmaceutica, y usos de estos compuestos para la elaboracion de medicamentos
GB0107228D0 (en) 2001-03-22 2001-05-16 Astrazeneca Ab Chemical compounds
SE0101038D0 (sv) 2001-03-23 2001-03-23 Astrazeneca Ab Novel compounds
SE0103818D0 (sv) 2001-11-15 2001-11-15 Astrazeneca Ab Chemical compounds
SE0301369D0 (sv) 2003-05-09 2003-05-09 Astrazeneca Ab Chemical compounds
TW200738634A (en) 2005-08-02 2007-10-16 Astrazeneca Ab New salt
NZ578204A (en) 2006-12-22 2012-05-25 Ironwood Pharmaceuticals Inc Compositions comprising bile acid sequestrants for treating esophageal disorders
WO2012027331A1 (en) 2010-08-27 2012-03-01 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
EP3991719A1 (en) 2013-01-15 2022-05-04 Ironwood Pharmaceuticals, Inc. Gastro-retentive sustained-release oral dosage form of a bile acid sequestrant

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3846430A (en) * 1968-01-12 1974-11-05 Bruneau & Cie Lab 1-(2-methoxy-phenyl)-4-{8 2-(4-fluoro-benzamido)-ethyl{9 -piperazine
JPS56158737A (en) * 1980-05-07 1981-12-07 Kowa Co Phenyl ester
JPS57203060A (en) * 1981-06-05 1982-12-13 Kowa Co Piperazine derivative
JPS595115A (ja) * 1982-06-30 1984-01-12 Kowa Co 糖尿病治療用薬剤
EP0071433A1 (en) * 1981-07-28 1983-02-09 Kowa Company, Ltd. Medicine for the treatment of diabetes
JPS5838243A (ja) * 1982-06-24 1983-03-05 Kowa Co フエニルエステル類
JPS58225079A (ja) * 1982-06-25 1983-12-27 Kowa Co ベンゾイルピペラジン類
AU545463B2 (en) * 1982-06-25 1985-07-18 Kowa Co. Ltd. Benzoyl piperacine esters
JPS58225080A (ja) * 1982-06-25 1983-12-27 Kowa Co ベンゾイルピペラジン誘導体

Also Published As

Publication number Publication date
EP0128007A2 (en) 1984-12-12
US4620005A (en) 1986-10-28
EP0128007A3 (en) 1987-12-02
ES532778A0 (es) 1985-09-01
CA1233467A (en) 1988-03-01
JPS59222484A (ja) 1984-12-14

Similar Documents

Publication Publication Date Title
ES8507132A1 (es) Proceso para producir un derivado de tetrahidronaftilcarboxilato de fenilo
TR199700844T1 (xx) Pirazolil-Benzoil T�revleri.
ES476343A1 (es) Procedimiento para la obtencion de ciclopentan-1-aminas
JPS53119844A (en) Optically active amino acid-mandelic acid complexes and theire preparation
FI853717L (fi) 3-amino-2-benzoyl- akrylsyraderivat och foerfarande foer deras framstaellning.
ES2012646A6 (es) Un procedimiento para la preparacion de derivados de piridazinona.
ES8707525A1 (es) Un procedimiento para la preparacion de nuevas isoindolinil-alquilpiperazinas
ES8401444A1 (es) "procedimiento para la preparacion de nuevas nitroanilinas".
ES8103030A1 (es) Un procedimiento para la preparacion de nuevos derivados de benzamida.
GB2122260B (en) Preventing damage to pumps by leakage
ES457805A1 (es) Un procedimiento para la preparacion de derivados de tiou- rea.
IE831145L (en) Pyridine derivatives
AU8512982A (en) Pyridine amides and esters
IE832254L (en) Fungicidal compounds
ES8802489A1 (es) Procedimiento para la obtencion de benzamidas
JPS5315325A (en) N-substituted phenylamino fatty acid derivatives
ES8206442A1 (es) Un procedimiento para la preparacion de derivados del acido amino ciclopropilcarboxilico.
ES428673A1 (es) Procedimiento para la obtencion de derivados de nitrobenzo-fenona sustituidos.
GB1556877A (en) Imidazothiazoles and thiazolopyrimidines
ES8708132A1 (es) Procedimiento para preparar n-fenil-4-fenil-1-piperazincarboxamidinas y compuestos afines como agentes anti-arritmicos
ES474973A1 (es) Procedimiento para la preparacion de nuevas isoquinoleindio-nas que contienen azufre.
ES8507539A1 (es) Proceso para producir indolcarboxilato de benzoil
ATE65986T1 (de) Propanolabkoemmlinge.
ES8604148A1 (es) Un metodo para preparar compuestos de 1,4-dihidropiridina
ES8507563A1 (es) Procedimiento para la obtencion de un derivado de arganofosfato