ES8604148A1 - Un metodo para preparar compuestos de 1,4-dihidropiridina - Google Patents

Un metodo para preparar compuestos de 1,4-dihidropiridina

Info

Publication number
ES8604148A1
ES8604148A1 ES544274A ES544274A ES8604148A1 ES 8604148 A1 ES8604148 A1 ES 8604148A1 ES 544274 A ES544274 A ES 544274A ES 544274 A ES544274 A ES 544274A ES 8604148 A1 ES8604148 A1 ES 8604148A1
Authority
ES
Spain
Prior art keywords
dihydro
dioxinyl
methoxymethyl
group
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES544274A
Other languages
English (en)
Other versions
ES544274A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INST ORGANICHESKOGO SINTEZA AK
Nikken Chemicals Co Ltd
Original Assignee
INST ORGANICHESKOGO SINTEZA AK
Nikken Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP3463983A external-priority patent/JPS59161378A/ja
Priority claimed from JP15240583A external-priority patent/JPS6045575A/ja
Application filed by INST ORGANICHESKOGO SINTEZA AK, Nikken Chemicals Co Ltd filed Critical INST ORGANICHESKOGO SINTEZA AK
Publication of ES544274A0 publication Critical patent/ES544274A0/es
Publication of ES8604148A1 publication Critical patent/ES8604148A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/12—1,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/08—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS DE 1,4-DIHIDROPIRIDINA, DE FORMULA (I), EN LA QUE R PUEDE SER UNO DE VARIOS TIPOS DE RADICALES; R1 Y R2 REPRESENTAN UN GRUPO METOXIMETILOXICARBONILO; Y R3 ES HIDROGENO O METOXIMETILO. CONSISTE EN LA REACCION DE UN ALDEHIDO DE FORMULA R-CHO EN LA QUE R TIENE EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), CON UN COMPUESTO DE FORMULA (II) Y CON UN COMPUESTO DE FORMULA (III), EN PRESENCIA O AUSENCIA DE UN DISOLVENTE ORGANICO INERTE; SEGUIDO DE LA HIDROLISIS DEL COMPUESTO FORMADO Y TRATAMIENTO DEL HIDROLIZADO RESULTANTE CON ETER CLOROMETILMETILICO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE ENFERMEDADES HEPATICAS.
ES544274A 1983-03-04 1985-06-17 Un metodo para preparar compuestos de 1,4-dihidropiridina Expired ES8604148A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3463983A JPS59161378A (ja) 1983-03-04 1983-03-04 １，４−ジヒドロピリジン化合物
JP15240583A JPS6045575A (ja) 1983-08-23 1983-08-23 １，４−ジヒドロピリジン化合物

Publications (2)

Publication Number Publication Date
ES544274A0 ES544274A0 (es) 1986-01-16
ES8604148A1 true ES8604148A1 (es) 1986-01-16

Family

ID=26373465

Family Applications (2)

Application Number Title Priority Date Filing Date
ES530247A Granted ES530247A0 (es) 1983-03-04 1984-03-02 Un metodo para preparar compuestos de 1, 4-dihidropiridina
ES544274A Expired ES8604148A1 (es) 1983-03-04 1985-06-17 Un metodo para preparar compuestos de 1,4-dihidropiridina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES530247A Granted ES530247A0 (es) 1983-03-04 1984-03-02 Un metodo para preparar compuestos de 1, 4-dihidropiridina

Country Status (3)

Country Link
EP (1) EP0118120B1 (es)
DE (1) DE3478685D1 (es)
ES (2) ES530247A0 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3716652A1 (de) * 1987-05-19 1988-12-08 Bayer Ag Dioxyalkylenaryl-dihydropyridine, zwischenprodukte zu ihrer herstellung, verfahren zu ihrer herstellung und ihre verwendung
DE68909873T2 (de) * 1988-07-28 1994-02-10 Nikken Chemicals Co Ltd 1,4-Dihydropyridin-Derivate.
GB9119983D0 (en) * 1991-09-19 1991-11-06 Erba Carlo Spa Dihydropyridine derivatives useful in antitumor therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58159490A (ja) * 1982-02-23 1983-09-21 Nikken Kagaku Kk １，４−ジヒドロピリジン化合物

Also Published As

Publication number Publication date
ES544274A0 (es) 1986-01-16
ES8601891A1 (es) 1985-11-01
EP0118120A2 (en) 1984-09-12
EP0118120A3 (en) 1987-07-22
DE3478685D1 (en) 1989-07-20
EP0118120B1 (en) 1989-06-14
ES530247A0 (es) 1985-11-01

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960401