ES8506016A1 - Un procedimiento para preparar derivados de acido 4, 7-dihidropirazolo (3, 4-b) piridin-5-carboxilico - Google Patents

Un procedimiento para preparar derivados de acido 4, 7-dihidropirazolo (3, 4-b) piridin-5-carboxilico

Info

Publication number
ES8506016A1
ES8506016A1 ES532124A ES532124A ES8506016A1 ES 8506016 A1 ES8506016 A1 ES 8506016A1 ES 532124 A ES532124 A ES 532124A ES 532124 A ES532124 A ES 532124A ES 8506016 A1 ES8506016 A1 ES 8506016A1
Authority
ES
Spain
Prior art keywords
pyrazolopyridines
pharmacologically active
new pharmacologically
new
antiangina
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES532124A
Other languages
English (en)
Other versions
ES532124A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA, Lepetit SpA filed Critical Gruppo Lepetit SpA
Publication of ES8506016A1 publication Critical patent/ES8506016A1/es
Publication of ES532124A0 publication Critical patent/ES532124A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE ACIDO 4,7-DIHIDROPIRAZOLO 3,4-BPIRIDIN-5-CARBOXILICO, DE FORMULA GENERAL (I), Y SUS SALES FISIOLOGICAMENTE ACEPTABLES DE LOS MISMOS.CONSISTE EN HACER REACCIONAR UN DERIVADO DE 5-AMINOPIRAZOL, DE FORMULA GENERAL (II), CON UN ALDEHIDO DE FORMULA: R2COH Y UN ESTER DE ACIDO ACETOACETICO DE FORMULA: CH3COCH2COOR3, EN UN DISOLVENTE ORGANICO INERTE, EN LA OSCURIDAD Y BAJO CORRIENTE DE NITROGENO.DE APLICACION EN TERAPEUTICA.
ES532124A 1982-12-20 1984-05-03 Un procedimiento para preparar derivados de acido 4, 7-dihidropirazolo (3, 4-b) piridin-5-carboxilico Granted ES532124A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8236131 1982-12-20

Publications (2)

Publication Number Publication Date
ES8506016A1 true ES8506016A1 (es) 1985-06-16
ES532124A0 ES532124A0 (es) 1985-06-16

Family

ID=10535093

Family Applications (2)

Application Number Title Priority Date Filing Date
ES528152A Granted ES528152A0 (es) 1982-12-20 1983-12-19 Un procedimiento para preparar derivados de acido 4,7-dihidropirazolo (3,4-b)piridin-5-carboxilico
ES532124A Granted ES532124A0 (es) 1982-12-20 1984-05-03 Un procedimiento para preparar derivados de acido 4, 7-dihidropirazolo (3, 4-b) piridin-5-carboxilico

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES528152A Granted ES528152A0 (es) 1982-12-20 1983-12-19 Un procedimiento para preparar derivados de acido 4,7-dihidropirazolo (3,4-b)piridin-5-carboxilico

Country Status (19)

Country Link
US (1) US4954508A (es)
EP (1) EP0114273B1 (es)
JP (1) JPH0660181B2 (es)
KR (1) KR890002227B1 (es)
AT (1) ATE69227T1 (es)
AU (1) AU574654B2 (es)
DE (1) DE3382452D1 (es)
DK (1) DK582083A (es)
ES (2) ES528152A0 (es)
FI (1) FI76337C (es)
GR (1) GR79111B (es)
IE (1) IE57305B1 (es)
IL (1) IL70445A (es)
MY (1) MY101250A (es)
NO (1) NO160367C (es)
NZ (1) NZ206626A (es)
PH (1) PH20896A (es)
PT (1) PT77850B (es)
ZA (1) ZA839092B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60197685A (ja) * 1984-03-19 1985-10-07 Shionogi & Co Ltd ４，７―ジヒドロピラゾロ［３，４―ｂ］ピリジン誘導体とその製造法
JPS5965089A (ja) * 1982-10-05 1984-04-13 Shionogi & Co Ltd ジヒドロピラゾロ〔３，４−ｂ〕ピリジン誘導体およびその製造法
US4873334A (en) * 1982-10-05 1989-10-10 Shionogi & Co., Ltd. 4,7-dihydropyrazolo(3,4-b) pyridine derivatives
JPS6056979A (ja) * 1983-09-08 1985-04-02 Shionogi & Co Ltd ４，７−ジヒドロピラゾロ〔３，４−ｂ〕ピリジン誘導体およびその製造法
US4918074A (en) * 1984-03-12 1990-04-17 Yoshitomi Pharmaceutical Industries, Ltd. Polyazaheterocycle compounds
US4916140A (en) * 1988-09-28 1990-04-10 Merrell Dow Pharmaceuticals Inc. Antiepileptic pyrazolopyridines
WO2002062795A2 (en) * 2001-02-02 2002-08-15 Mitsubishi Pharma Corporation Dihydropyrazolopyridine compounds and pharmaceutical use thereof
US6977262B2 (en) 2001-02-02 2005-12-20 Mitsubishi Pharma Corporation Dihydropyrazolopyridine compounds and pharmaceutical use thereof
KR20060070486A (ko) * 2003-06-13 2006-06-23 젠타리스 게엠베하 포스파티딜이노시톨 3-키나제의 억제 활성을 갖는 화합물및 이의 사용 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773778A (en) * 1972-01-24 1973-11-20 Squibb & Sons Inc Sulfur derivatives of pyrazolo (3,4-b)pyridines
DE2356684A1 (de) * 1972-11-15 1974-05-16 Heyden Chem Fab Neue 4-aminoderivate von pyrazolo (3,4-b)pyridin-5-carboxamiden
US4038283A (en) * 1975-04-30 1977-07-26 E. R. Squibb & Sons, Inc. 4-Alkoxy or hydroxy derivatives of 2H-pyrazolo[3,4-b]pyridine-5-carboxylic acids and esters
GB1568399A (en) * 1975-10-16 1980-05-29 Squibb & Sons Inc Pyrazolo pyridine derivatives
US4020072A (en) * 1976-05-04 1977-04-26 E. R. Squibb & Sons, Inc. 5-Aminomethyl-1H-pyrazolo[3,4-b]pyridines
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
JPS5965089A (ja) * 1982-10-05 1984-04-13 Shionogi & Co Ltd ジヒドロピラゾロ〔３，４−ｂ〕ピリジン誘導体およびその製造法

Also Published As

Publication number Publication date
IE57305B1 (en) 1992-07-15
DE3382452D1 (de) 1991-12-12
US4954508A (en) 1990-09-04
MY101250A (en) 1991-08-17
NO160367B (no) 1989-01-02
ZA839092B (en) 1984-07-25
JPS59118786A (ja) 1984-07-09
IE832988L (en) 1984-06-20
NZ206626A (en) 1986-11-12
GR79111B (es) 1984-10-02
JPH0660181B2 (ja) 1994-08-10
ES8601987A1 (es) 1985-11-16
EP0114273B1 (en) 1991-11-06
KR890002227B1 (ko) 1989-06-24
FI76337B (fi) 1988-06-30
PT77850B (en) 1986-05-08
PT77850A (en) 1984-01-01
IL70445A0 (en) 1984-03-30
EP0114273A1 (en) 1984-08-01
NO834695L (no) 1984-06-21
PH20896A (en) 1987-05-27
FI834661A0 (fi) 1983-12-19
NO160367C (no) 1989-04-12
AU574654B2 (en) 1988-07-14
IL70445A (en) 1988-12-30
ES528152A0 (es) 1985-11-16
ATE69227T1 (de) 1991-11-15
FI76337C (fi) 1988-10-10
DK582083A (da) 1984-06-21
KR840007000A (ko) 1984-12-04
AU2227083A (en) 1984-06-28
FI834661A (fi) 1984-06-21
DK582083D0 (da) 1983-12-16
ES532124A0 (es) 1985-06-16

Similar Documents

Publication Publication Date Title
ES8603477A1 (es) Procedimiento para preparar una 1h-imidazo (4, 5-c) quinolin-4-amina
NZ214612A (en) Piperazine derivatives and pharmaceutical compositions
HUT46657A (en) Process for producing antitumour pharmaceutical compositions comprising sulfonyl-urea derivatives as active ingredient
HUT48266A (en) Process for producing 2,3'-dideoxy-2'-fluoronukleozides and pharmaceutical compositions containing them as active componenets
EP0104522A3 (en) New pyrazolo(3,4-b)pyridine derivatives and process for producing them
ES8506016A1 (es) Un procedimiento para preparar derivados de acido 4, 7-dihidropirazolo (3, 4-b) piridin-5-carboxilico
PT80191A (en) Process for preparing substituted benzopyrans useful as medicaments
HUT46224A (en) Process for producing pharmaceutical compositions containing prostaglandin e1-derivatives
HUT39437A (en) Process for producing new morpholinol derivatives and pharmaceutical compositions containing them as active agents
PT81954A (en) Process for the preparation of pharmaceutical compositions containing 9,10-dihydro alkalloids of ergot
IL75874A0 (en) Naphthyl analogs of mevalonolactone and derivatives thereof,their production and pharmaceutical compositions containing them
ES8703874A1 (es) Un procedimiento para preparar pirazol(3,4,5-kl)acridinas
HUT47117A (en) Process for producing substituted thiacycloalkeno(3,2-b) pyridine derivatives and pharmaceutical compositions comprising these compounds as active ingredient
IE56229B1 (en) 2-piperazinyl-or-homopiperazinyl-quinazoline derivatives their production and pharmaceutical compositions containing them
ES8605518A1 (es) Procedimiento para preparar derivados de 4-oxo-pirido(2,3-d)pirimidina
IE43872L (en) 2,9-dioxatricyclo [4.3.1.0(3,7)] decanes
ES8705457A1 (es) Procedimiento para producir nuevos derivados de antibioticosdel grupo de la pluramicina
IL74215A (en) Derivatives of 5-phenyltetrazolo(1,5-a)(1,2,4)triazolo(1,5-c)pyrimidine-6-alkanols and pharmaceutical compositions containing them
ES8203371A1 (es) Procedimiento de preparar indolo(2,3,3,4)pirido(2,1-b)quina-zolin-5-onas

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519