ES8504452A1 - Procedimiento para la obtencion de productos farmaceuticos solidos a base de particulas esfericas. - Google Patents

Procedimiento para la obtencion de productos farmaceuticos solidos a base de particulas esfericas.

Info

Publication number
ES8504452A1
ES8504452A1 ES529959A ES529959A ES8504452A1 ES 8504452 A1 ES8504452 A1 ES 8504452A1 ES 529959 A ES529959 A ES 529959A ES 529959 A ES529959 A ES 529959A ES 8504452 A1 ES8504452 A1 ES 8504452A1
Authority
ES
Spain
Prior art keywords
solution
single crystals
assistants
organic
crystals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES529959A
Other languages
English (en)
Spanish (es)
Other versions
ES529959A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of ES529959A0 publication Critical patent/ES529959A0/es
Publication of ES8504452A1 publication Critical patent/ES8504452A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Metallurgy (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Oxygen, Ozone, And Oxides In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Jellies, Jams, And Syrups (AREA)
ES529959A 1983-02-23 1984-02-22 Procedimiento para la obtencion de productos farmaceuticos solidos a base de particulas esfericas. Expired ES8504452A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833306250 DE3306250A1 (de) 1983-02-23 1983-02-23 Sphaerische einkristalle fuer pharmazeutische zwecke

Publications (2)

Publication Number Publication Date
ES529959A0 ES529959A0 (es) 1985-04-16
ES8504452A1 true ES8504452A1 (es) 1985-04-16

Family

ID=6191601

Family Applications (1)

Application Number Title Priority Date Filing Date
ES529959A Expired ES8504452A1 (es) 1983-02-23 1984-02-22 Procedimiento para la obtencion de productos farmaceuticos solidos a base de particulas esfericas.

Country Status (11)

Country Link
US (1) US4632843A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0119480B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS59182290A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE40291T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU561079B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1220421A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE3306250A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES8504452A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL71018A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT78146B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA841287B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0265061B1 (en) * 1986-09-18 1992-01-08 London School of Pharmacy Innovations Ltd Pharmaceutical formulation
GB8628728D0 (en) * 1986-12-02 1987-01-07 Euro Celtique Sa Spheroids
US4874613A (en) * 1987-03-06 1989-10-17 Baker Cummins Pharmaceuticals, Inc. Taste concealing pharmaceutical dosage unit
FR2613619B1 (fr) * 1987-04-07 1993-10-15 Recherche Informatique Pharmacie Medicaments, produits dietetiques ou produits d'hygiene sous forme de compositions pulverulentes obtenues par adsorption de principes actifs sur un sucre a dissolution rapide
IL86211A (en) * 1987-05-04 1992-03-29 Ciba Geigy Ag Oral forms of administration for carbamazepine in the forms of stable aqueous suspension with delayed release and their preparation
GB8805695D0 (en) * 1988-03-10 1988-04-07 Nycomed As Enteric coated spheroidal granules
DE3911069A1 (de) * 1989-04-06 1990-10-11 Knoll Ag Einkristalle von ss-phenylpropiophenonen
DE4027927A1 (de) * 1990-09-04 1992-03-05 Bayer Ag Brausekomponente und verfahren zu ihrer herstellung
JP3447042B2 (ja) * 1997-07-23 2003-09-16 フロイント産業株式会社 単一物質球形粒の製造方法
DE19834876A1 (de) * 1998-08-01 2000-02-03 Aventis Res & Tech Gmbh & Co Verfahren zur Herstellung sphärischer Teilchen bei der Kristallisation
DE19901687B4 (de) 1999-01-18 2006-06-01 Grünenthal GmbH Opioide Analgetika mit kontrollierter Wirkstofffreisetzung
US7001892B1 (en) 1999-06-11 2006-02-21 Purdue Research Foundation Pharmaceutical materials and methods for their preparation and use
WO2000076480A2 (en) * 1999-06-11 2000-12-21 Eli Lilly And Company Pharmaceutical materials and methods for their preparation and use
FI20002217L (fi) * 1999-12-30 2001-07-01 Orion Yhtymae Oyj Inhalaatiopartikkelit
FI20010115A0 (fi) * 2001-01-18 2001-01-18 Orion Corp Menetelmä nanopartikkelien valmistamiseksi
US7122681B2 (en) * 2002-02-19 2006-10-17 Teva Pharmaceutical Industries, Ltd. Desolvation process for the production of atorvastatin hemi-calcium essentially free of bound organic solvent
DE10218106A1 (de) * 2002-04-23 2003-11-20 Jenapharm Gmbh Verfahren zum Herstellen von Kristallen von Arzneimittelwirkstoffen, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen
DE10218110A1 (de) * 2002-04-23 2003-11-20 Jenapharm Gmbh Verfahren zum Herstellen von Kristallen von Arzneimittelhilfsstoffen, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen
EP1499300B1 (en) * 2002-04-29 2009-03-18 Supernus Pharmaceuticals, Inc. Pharmaceutical formulations with improved bioavailability
AT504996B1 (de) * 2007-03-02 2009-03-15 Andritz Tech & Asset Man Gmbh Verfahren und vorrichtung zur trocknung von kristallinen carbonsäuren
US20080268018A1 (en) * 2007-04-30 2008-10-30 Pacetti Stephen D Method for forming crystallized therapeutic agents on a medical device
EP2223702B1 (en) * 2007-12-03 2019-05-08 Tomita Pharmaceutical Co., Ltd. Core particle for pharmaceutical preparation
CA2691554A1 (en) * 2010-02-01 2011-08-01 Michael Krautter Crystal growing device
US9905953B1 (en) 2016-09-30 2018-02-27 Slobodan Pavlovic High power spring-actuated electrical connector
AU2017339373A1 (en) * 2016-10-03 2019-04-18 Hoganas Ab (Publ) White iron food additive
MX2020008873A (es) 2018-02-26 2021-01-08 Royal Prec Products Llc Conector electrico accionado por resorte para aplicaciones con potencia alta.
CN111498874B (zh) * 2020-02-21 2022-10-04 天津大学 一种大粒度碘化铯球晶及其制备方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA799930A (en) * 1968-11-26 Polderman Jacobus Process for rendering powders free flowing and the thus obtained powders
US2996431A (en) * 1953-12-16 1961-08-15 Barry Richard Henry Friable tablet and process for manufacturing same
US2853420A (en) * 1956-01-25 1958-09-23 Lowey Hans Ethyl cellulose coatings for shaped medicinal preparations
US3072533A (en) * 1960-11-15 1963-01-08 Henry J Johnson Crystalline vitamin d composition and method of preparing same
NL137432C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1964-08-13 1900-01-01
US3433872A (en) * 1966-11-25 1969-03-18 Hoffmann La Roche Palatable,free-flowing,non-agglomerating caffeine powder
FR7932M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1968-09-30 1970-05-19
US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
CA942667A (en) * 1970-10-16 1974-02-26 Alejandro Zaffaroni Drug-delivery system
US3909444A (en) * 1971-08-05 1975-09-30 Ncr Co Microcapsule
FR2171934B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1972-02-16 1974-09-13 Rhone Poulenc Sa
US4123382A (en) * 1973-05-25 1978-10-31 Merck & Co., Inc. Method of microencapsulation
JPS53124634A (en) * 1974-08-15 1978-10-31 Shin Nihon Kagaku Kogyo Kk Production of table salt
JPS51113813A (en) * 1975-03-03 1976-10-07 Towa Kasei Kogyo Kk Pulverizing process of maltitol
SE418247B (sv) * 1975-11-17 1981-05-18 Haessle Ab Sett att framstella kroppar med reglerad frigoring av en aktiv komponent
DD146547A5 (de) * 1978-07-15 1981-02-18 Boehringer Sohn Ingelheim Arzneimittel-retardform mit unloeslichen poroesen diffusionshuellen
US4386120A (en) * 1980-01-07 1983-05-31 Nippon Kayaku Kabushiki Kaisha Process for producing polyacrylic acid salt granules easily soluble in water
DE3000979A1 (de) * 1980-01-12 1981-07-23 Dr. Karl Thomae Gmbh, 7950 Biberach Neue dipyridamol-retardformen und verfahren zu ihrer herstellung
US4259315A (en) * 1980-06-13 1981-03-31 A. H. Robins Company, Inc. Controlled release potassium dosage form
US4479911A (en) * 1982-01-28 1984-10-30 Sandoz, Inc. Process for preparation of microspheres and modification of release rate of core material

Also Published As

Publication number Publication date
IL71018A (en) 1987-01-30
CA1220421A (en) 1987-04-14
EP0119480B1 (de) 1989-01-25
AU561079B2 (en) 1987-04-30
JPH0573727B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-10-15
AU2484384A (en) 1984-08-30
DE3306250A1 (de) 1984-08-23
ZA841287B (en) 1984-10-31
US4632843A (en) 1986-12-30
ES529959A0 (es) 1985-04-16
ATE40291T1 (de) 1989-02-15
EP0119480A3 (en) 1985-09-25
PT78146A (en) 1984-03-01
DE3476337D1 (en) 1989-03-02
PT78146B (en) 1986-05-19
EP0119480A2 (de) 1984-09-26
IL71018A0 (en) 1984-05-31
JPS59182290A (ja) 1984-10-17

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20050212