ES8504213A1 - Procedimiento de preparacion de tioesteres de hidrocortisona - Google Patents

Procedimiento de preparacion de tioesteres de hidrocortisona

Info

Publication number
ES8504213A1
ES8504213A1 ES534854A ES534854A ES8504213A1 ES 8504213 A1 ES8504213 A1 ES 8504213A1 ES 534854 A ES534854 A ES 534854A ES 534854 A ES534854 A ES 534854A ES 8504213 A1 ES8504213 A1 ES 8504213A1
Authority
ES
Spain
Prior art keywords
preparation
thiocarboxylyc
hydrocortisone
medicines
carboxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES534854A
Other languages
English (en)
Other versions
ES534854A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jouveinal SA
Original Assignee
Jouveinal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jouveinal SA filed Critical Jouveinal SA
Publication of ES8504213A1 publication Critical patent/ES8504213A1/es
Publication of ES534854A0 publication Critical patent/ES534854A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Television Signal Processing For Recording (AREA)
  • Earth Drilling (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Inert Electrodes (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE 21-TIOACETATO 17-BUTIRATO DE 3,20-DIONA 11 BETA-HIDROXI-PREGN-4-ENO Y EL 21-TIOPROPIONATO 17-BUTIRATO DE 3,20-DIONA 11-BETA-HIDROXI-PREGN-4-ENO.SE OBTIENEN POR REACCION DE CONDENSACION DEL 21-SULFONATO DE ESTEROIDE DE FORMULA 0), DONDE R ES UN RADICAL ALCOILO CON 1 A 6 ATOMOS DE CARBONO, CON UN TIOCARBOXILATO DE METAL ALCALINO DE FORMULA (II) EN LA QUE M ES UN ATOMO DE METAL ALCALINO Y R1 ES METILO O ETILO. SE EMPLEA UN DISOLVENTE APROTICO.DE APLICACION COMO PRODUCTOS ANTIINFLAMATORIOS.
ES534854A 1983-08-26 1984-08-03 Procedimiento de preparacion de tioesteres de hidrocortisona Granted ES534854A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8313777A FR2551069B1 (fr) 1983-08-26 1983-08-26 17-oxo-21-thioesters d'hydrocortisone, leur preparation et leurs applications comme medicament

Publications (2)

Publication Number Publication Date
ES8504213A1 true ES8504213A1 (es) 1985-04-16
ES534854A0 ES534854A0 (es) 1985-04-16

Family

ID=9291831

Family Applications (1)

Application Number Title Priority Date Filing Date
ES534854A Granted ES534854A0 (es) 1983-08-26 1984-08-03 Procedimiento de preparacion de tioesteres de hidrocortisona

Country Status (12)

Country Link
US (2) US4933331A (es)
EP (1) EP0141684B1 (es)
JP (1) JPS6048999A (es)
AT (1) ATE30031T1 (es)
AU (1) AU561870B2 (es)
DE (1) DE3466541D1 (es)
ES (1) ES534854A0 (es)
FI (1) FI80889C (es)
FR (1) FR2551069B1 (es)
HU (1) HU189930B (es)
IE (1) IE57603B1 (es)
PT (1) PT79100B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861765A (en) * 1985-06-26 1989-08-29 Jouveinal 21-alkyl-, cycloalkyl- or aryl-substituted thio steroids and pharmaceutical compositions containing them
US5439901A (en) * 1993-07-23 1995-08-08 The Procter & Gamble Company Cyproterone thiopivalate
US5344651A (en) * 1993-07-23 1994-09-06 The Procter & Gamble Company Cyproterone acetate thioacetate
US5420120A (en) * 1993-12-17 1995-05-30 Alcon Laboratories, Inc. Anti-inflammatory glucocorticoid compounds for topical ophthalmic use
US5653961A (en) * 1995-03-31 1997-08-05 Minnesota Mining And Manufacturing Company Butixocort aerosol formulations in hydrofluorocarbon propellant
US5981517A (en) * 1996-05-09 1999-11-09 Soft Drugs, Inc. Androstene derivatives
CA2710240A1 (en) * 2007-12-21 2009-07-09 Schering Corporation C-21 thioethers as glucocorticoid receptor agonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH566349A5 (es) * 1969-12-24 1975-09-15 Ciba Geigy Ag
FR2231374B1 (es) * 1973-05-30 1976-10-22 Jouveinal Sa
FR2510582B1 (fr) * 1981-07-30 1986-05-30 Sipsy Steroides esterifies en la position 17 et thio-esterifies en la position 21, leur procede de preparation et leur application comme medicament
FR2529894B2 (fr) * 1981-07-30 1986-07-25 Jouveinal Steroides esterifies en la position 17 et thio-esterifies en la position 21 et leur application comme medicament

Also Published As

Publication number Publication date
US4933331A (en) 1990-06-12
EP0141684A1 (fr) 1985-05-15
AU3096484A (en) 1985-02-28
JPS6048999A (ja) 1985-03-16
HU189930B (en) 1986-08-28
FI843246A (fi) 1985-02-27
HUT34996A (en) 1985-05-28
FI80889B (fi) 1990-04-30
FI80889C (fi) 1990-08-10
IE57603B1 (en) 1993-01-27
IE841769L (en) 1985-02-26
ATE30031T1 (de) 1987-10-15
FI843246A0 (fi) 1984-08-16
JPH0419238B2 (es) 1992-03-30
AU561870B2 (en) 1987-05-21
PT79100A (fr) 1984-09-01
DE3466541D1 (en) 1987-11-05
ES534854A0 (es) 1985-04-16
EP0141684B1 (fr) 1987-09-30
FR2551069B1 (fr) 1986-07-25
US5021408A (en) 1991-06-04
PT79100B (fr) 1986-07-17
FR2551069A1 (fr) 1985-03-01

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