ES8502113A1 - Procedimiento para la preparacion de un derivado xantinico. - Google Patents

Procedimiento para la preparacion de un derivado xantinico.

Info

Publication number
ES8502113A1
ES8502113A1 ES523854A ES523854A ES8502113A1 ES 8502113 A1 ES8502113 A1 ES 8502113A1 ES 523854 A ES523854 A ES 523854A ES 523854 A ES523854 A ES 523854A ES 8502113 A1 ES8502113 A1 ES 8502113A1
Authority
ES
Spain
Prior art keywords
xanthine derivatives
brochodilator
mucolytic
thiophene
esterification
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES523854A
Other languages
English (en)
Other versions
ES523854A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fordonal SA
Original Assignee
Fordonal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fordonal SA filed Critical Fordonal SA
Priority to ES523854A priority Critical patent/ES523854A0/es
Priority to GB08417008A priority patent/GB2143233A/en
Priority to FR8410593A priority patent/FR2554449A1/fr
Priority to IT21743/84A priority patent/IT1180197B/it
Priority to DE19843424620 priority patent/DE3424620A1/de
Priority to JP59137377A priority patent/JPS6084290A/ja
Priority to KR1019840003861A priority patent/KR850001197A/ko
Publication of ES8502113A1 publication Critical patent/ES8502113A1/es
Publication of ES523854A0 publication Critical patent/ES523854A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UN DERIVADO XANTINICO Y MAS ESPECIALMENTE DE LA 7-2-(2-TENOILOXI)PROPILTEOFILINA, DE FORMULA GENERAL (I).CONSISTE EN HACER REACCIONAR LA 7-(2-HIDROXIPROPIL)-TEOFILINA, DE FORMULA (II), CON UN DERIVADO REACTIVO DEL ACIDO 2-TIOFENCARBOXILICO, EFECTUANDOSE DICHA REACCION A UNA TEMPERATURA COMPRENDIDA ENTRE 10 Y 90 GRADOS EN EL SENO DE UN DISOLVENTE ORGANICO INERTE, TAL COMO ACETONA, DIOXANO, CLORURO DE METILENO, BENCENO, TOLUENO O PIRIDINA.DE APLICACION EN EL TRATAMIENTO DE ENFERMEDADES DEL APARATO RESPIRATORIO, TAL COMO LA BRONQUITIS CRONICA OBSTRUCTIVA.
ES523854A 1983-07-05 1983-07-05 Procedimiento para la preparacion de un derivado xantinico. Granted ES523854A0 (es)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ES523854A ES523854A0 (es) 1983-07-05 1983-07-05 Procedimiento para la preparacion de un derivado xantinico.
GB08417008A GB2143233A (en) 1983-07-05 1984-07-04 Xanthine derivatives
FR8410593A FR2554449A1 (fr) 1983-07-05 1984-07-04 Derive de la xanthine
IT21743/84A IT1180197B (it) 1983-07-05 1984-07-04 Derivati della xantina
DE19843424620 DE3424620A1 (de) 1983-07-05 1984-07-04 Xanthinderivat, verfahren zu seiner herstellung und es enthaltende pharmazeutische zubereitungen
JP59137377A JPS6084290A (ja) 1983-07-05 1984-07-04 キサンテイン誘導体及びその製造方法、並びに医薬用キサンテイン含有組成物
KR1019840003861A KR850001197A (ko) 1983-07-05 1984-07-04 크산틴 유도체의 제조방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES523854A ES523854A0 (es) 1983-07-05 1983-07-05 Procedimiento para la preparacion de un derivado xantinico.

Publications (2)

Publication Number Publication Date
ES8502113A1 true ES8502113A1 (es) 1984-12-16
ES523854A0 ES523854A0 (es) 1984-12-16

Family

ID=8485967

Family Applications (1)

Application Number Title Priority Date Filing Date
ES523854A Granted ES523854A0 (es) 1983-07-05 1983-07-05 Procedimiento para la preparacion de un derivado xantinico.

Country Status (7)

Country Link
JP (1) JPS6084290A (es)
KR (1) KR850001197A (es)
DE (1) DE3424620A1 (es)
ES (1) ES523854A0 (es)
FR (1) FR2554449A1 (es)
GB (1) GB2143233A (es)
IT (1) IT1180197B (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2097015A1 (en) * 1970-07-27 1972-03-03 Investigations Sci Pharm Esters of 7-(2,3-dihydroxypropyl)theophylline - cardiovascular and respiratory system active
DE3037391A1 (de) * 1980-10-03 1982-05-19 King Consult GmbH, 5000 Köln Ester von 7-hydroxyalkyl-1,3-dimethylxanthinen, verfahren zu ihrer herstellung und ihre verwendung als lipidsenkende mittel

Also Published As

Publication number Publication date
IT8421743A0 (it) 1984-07-04
FR2554449A1 (fr) 1985-05-10
GB2143233A (en) 1985-02-06
DE3424620A1 (de) 1985-01-17
JPS6084290A (ja) 1985-05-13
IT8421743A1 (it) 1986-01-04
IT1180197B (it) 1987-09-23
GB8417008D0 (en) 1984-08-08
KR850001197A (ko) 1985-03-16
ES523854A0 (es) 1984-12-16

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