ES8502159A1 - Un metodo para preparar un derivado 14-acilico de lankacidina. - Google Patents

Un metodo para preparar un derivado 14-acilico de lankacidina.

Info

Publication number
ES8502159A1
ES8502159A1 ES521361A ES521361A ES8502159A1 ES 8502159 A1 ES8502159 A1 ES 8502159A1 ES 521361 A ES521361 A ES 521361A ES 521361 A ES521361 A ES 521361A ES 8502159 A1 ES8502159 A1 ES 8502159A1
Authority
ES
Spain
Prior art keywords
lankacidins
productions
improvement
lankacidin
cultivated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES521361A
Other languages
English (en)
Other versions
ES521361A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ES8502159A1 publication Critical patent/ES8502159A1/es
Publication of ES521361A0 publication Critical patent/ES521361A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

METODO PARA PRODUCIR ANTIBIOTICOS DE LANKACIDINA, DE FORMULAS ESTRUCTURALES (I) Y (II).CONSISTE EN CULTIVAR UN MICROORGANISMO CAPAZ DE PRODUCIR LANKACIDINA EN UN MEDIO DE CULTIVO QUE CONTIENE CICLODEXTRINA, Y SI SE DESEA, SE AN/ADE UN CARBOXILATO DE ALQUILO INFERIOR AL CALDO DE CULTIVO O FILTRADO DEL MISMO RESULTANTE, PARA ENRIQUECER EL CONTENIDO DEL DERIVADO 14-ACILICO DE LANKACIDINA.DE APLICACION COMO AGENTES ANTIBACTERIANOS Y ANTITUMORALES.
ES521361A 1982-04-12 1983-04-11 Un metodo para preparar un derivado 14-acilico de lankacidina. Granted ES521361A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57061342A JPS58179496A (ja) 1982-04-12 1982-04-12 ランカシジンの改良製造法

Publications (2)

Publication Number Publication Date
ES8502159A1 true ES8502159A1 (es) 1984-12-16
ES521361A0 ES521361A0 (es) 1984-12-16

Family

ID=13168356

Family Applications (1)

Application Number Title Priority Date Filing Date
ES521361A Granted ES521361A0 (es) 1982-04-12 1983-04-11 Un metodo para preparar un derivado 14-acilico de lankacidina.

Country Status (11)

Country Link
US (1) US4480033A (es)
EP (1) EP0091781B1 (es)
JP (1) JPS58179496A (es)
KR (1) KR920009510B1 (es)
CA (1) CA1190165A (es)
DE (1) DE3367618D1 (es)
DK (1) DK160510C (es)
ES (1) ES521361A0 (es)
HU (1) HU192960B (es)
SG (1) SG86088G (es)
ZA (1) ZA832470B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61271986A (ja) * 1985-05-27 1986-12-02 Agency Of Ind Science & Technol リンパ系細胞用培地
US4914206A (en) * 1985-10-06 1990-04-03 Takeda Chemical Industries, Ltd. Lankacidin derivatives and production thereof
EP0226896B1 (en) * 1985-12-05 1993-09-15 Takeda Chemical Industries, Ltd. Lankacidin derivatives and production thereof
EP0269453B1 (en) * 1986-11-28 1993-03-17 Takeda Chemical Industries, Ltd. A process for producing carboxylic acid esters
US5436140A (en) * 1988-02-02 1995-07-25 Fujisawa Pharmaceutical Co., Ltd. Process for producing WS-9326A and WS-9326B
US5217952A (en) * 1988-02-02 1993-06-08 Fujisawa Pharmaceutical Co., Ltd. Peptides WS-9326a and WS-9326b, derivatives thereof and uses thereof
US6683100B2 (en) 1999-01-19 2004-01-27 Novartis Ag Organic compounds
US6194181B1 (en) 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
EP1710244A4 (en) * 2004-01-29 2009-06-17 Eisai R&D Man Co Ltd METHOD FOR STABILIZING A MACROLIDE COVERAGE

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3188272A (en) * 1954-11-29 1965-06-08 Univ Illinois Antibiotic filipin
DK117626C (da) * 1967-05-18 1970-10-19 Takeda Chemical Industries Ltd Fremgangsmåde til fremstilling af det antibiotiske stof T-2636 eller dets komponenter.
JPS4810442B1 (es) * 1968-10-26 1973-04-03

Also Published As

Publication number Publication date
DK158983D0 (da) 1983-04-11
CA1190165A (en) 1985-07-09
EP0091781B1 (en) 1986-11-12
DK160510B (da) 1991-03-18
US4480033A (en) 1984-10-30
SG86088G (en) 1989-06-16
ES521361A0 (es) 1984-12-16
JPS58179496A (ja) 1983-10-20
EP0091781A1 (en) 1983-10-19
JPS6314950B2 (es) 1988-04-02
KR840004442A (ko) 1984-10-15
DK158983A (da) 1983-10-13
HU192960B (en) 1987-08-28
DK160510C (da) 1991-08-26
KR920009510B1 (ko) 1992-10-17
DE3367618D1 (en) 1987-01-02
ZA832470B (en) 1983-12-28

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