ES8500885A1 - Procedimiento para la preparacion de n-metil-n-bis-(3,4-dimetoxi-fenil-etil)-amina - Google Patents

Procedimiento para la preparacion de n-metil-n-bis-(3,4-dimetoxi-fenil-etil)-amina

Info

Publication number
ES8500885A1
ES8500885A1 ES524353A ES524353A ES8500885A1 ES 8500885 A1 ES8500885 A1 ES 8500885A1 ES 524353 A ES524353 A ES 524353A ES 524353 A ES524353 A ES 524353A ES 8500885 A1 ES8500885 A1 ES 8500885A1
Authority
ES
Spain
Prior art keywords
compounds
compound
blocking activity
calcium blocking
calcium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES524353A
Other languages
English (en)
Other versions
ES524353A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sir International SA
Yason SRL
Original Assignee
Sir International SA
Yason SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT22339/82A external-priority patent/IT1218324B/it
Priority claimed from IT8320838A external-priority patent/IT1206322B/it
Application filed by Sir International SA, Yason SRL filed Critical Sir International SA
Publication of ES524353A0 publication Critical patent/ES524353A0/es
Publication of ES8500885A1 publication Critical patent/ES8500885A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE N-METIL-N-BIS-(3,4-DIMETOXI-FENIL)-AMINA, DE FORMULA GENERAL (I), Y SUS SALES FARMACEUTICAMENTE ACEPTABLES.CONSISTE EN HACER REACCIONAR UN BIS-2-(3,4-DIMETOXIFENIL)ETILAMINA, CON FORMALDEHIDO EN UN AMBIENTE REDUCTOR. COMO AGENTE REDUCTOR SE PUEDE UTILIZAR UN BOROHIDRURO SODICO.DE APLICACION EN LA TERAPEUTICA DE LOS TRASTORNOS CARDIOVASCULARES Y DE LAS IRREGULARIDADES DE LA CIRCULACION CEREBRAL.
ES524353A 1982-07-09 1983-07-08 Procedimiento para la preparacion de n-metil-n-bis-(3,4-dimetoxi-fenil-etil)-amina Expired ES8500885A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT22339/82A IT1218324B (it) 1982-07-09 1982-07-09 Composti ad attivita' calcio-antagonista,metodo per la loro preparazione e composizioni farmaceutiche
IT8320838A IT1206322B (it) 1983-04-28 1983-04-28 Composti ad attivita' bloccante del calcio a livello cardiaco e cerebrale, metodo per la loro preparazione e composizioni farmaceutiche.

Publications (2)

Publication Number Publication Date
ES524353A0 ES524353A0 (es) 1984-11-16
ES8500885A1 true ES8500885A1 (es) 1984-11-16

Family

ID=26327676

Family Applications (1)

Application Number Title Priority Date Filing Date
ES524353A Expired ES8500885A1 (es) 1982-07-09 1983-07-08 Procedimiento para la preparacion de n-metil-n-bis-(3,4-dimetoxi-fenil-etil)-amina

Country Status (8)

Country Link
US (1) US4956389A (es)
CA (1) CA1238858A (es)
CH (1) CH654294A5 (es)
DE (1) DE3324727A1 (es)
ES (1) ES8500885A1 (es)
FR (1) FR2541113B1 (es)
GB (1) GB2126213B (es)
NL (1) NL185666C (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3630903A1 (de) * 1986-09-11 1988-03-24 Thomae Gmbh Dr K Neue tetrahydronaphthalin- und indanderivate, verfahren zu deren herstellung sowie diese enthaltende arzneimittel
FR2646347B1 (fr) * 1989-04-28 1991-08-23 Roussel Uclaf Nouveau derive d'hydroxyphenethylamine et ses sels, procede de preparation, application a titre de medicaments et utilisation comme outil pharmacologique specifique

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2006114A (en) * 1931-04-27 1935-06-25 Rosenmund Karl Wilhelm Aliphatic-aromatic amine and process of making same
DE617647C (de) * 1931-04-30 1935-08-23 Karl Rosenmund Dr Verfahren zur Darstellung von sekundaeren und tertiaeren Aminen der fettaromatischen Reihe
NL6813366A (es) * 1967-11-13 1969-05-16
US4181738A (en) * 1976-11-30 1980-01-01 Cornell Research Foundation, Inc. Catecholamine derivatives, a process for their preparation and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
GB2126213B (en) 1986-01-29
GB2126213A (en) 1984-03-21
ES524353A0 (es) 1984-11-16
US4956389A (en) 1990-09-11
NL8302451A (nl) 1984-02-01
CA1238858A (en) 1988-07-05
NL185666B (nl) 1990-01-16
CH654294A5 (it) 1986-02-14
FR2541113B1 (fr) 1986-11-14
DE3324727A1 (de) 1984-01-12
FR2541113A1 (fr) 1984-08-24
NL185666C (nl) 1990-06-18
GB8318467D0 (en) 1983-08-10
DE3324727C2 (es) 1988-09-22

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20001009