ES8500240A1 - Procedimiento para la obtencion de compuestos derivados del acido 3-hidroxibutanoico. - Google Patents

Procedimiento para la obtencion de compuestos derivados del acido 3-hidroxibutanoico.

Info

Publication number
ES8500240A1
ES8500240A1 ES519991A ES519991A ES8500240A1 ES 8500240 A1 ES8500240 A1 ES 8500240A1 ES 519991 A ES519991 A ES 519991A ES 519991 A ES519991 A ES 519991A ES 8500240 A1 ES8500240 A1 ES 8500240A1
Authority
ES
Spain
Prior art keywords
hydroxybutanoic acid
pharmaceutical compositions
medicaments
salts
compounds derived
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES519991A
Other languages
English (en)
Other versions
ES519991A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Solvay SA
Original Assignee
Solvay SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay SA filed Critical Solvay SA
Publication of ES519991A0 publication Critical patent/ES519991A0/es
Publication of ES8500240A1 publication Critical patent/ES8500240A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DEL ACIDO 3-HIDROXIBUTANOICO Y DE UNA BASE INORGANICA, U ORGANICA NITROGENADA.CONSISTE EN LA REACCION EQUIMOLECULAR DE ACIDO 3-HIDROXIBUTANOICO Y UNA BASE INORGANICA U ORGANICA NITROGENADA, EN UN DISOLVENTE TAL COMO AGUA, A UNA TEMPERATURA ENTRE 20JC Y 80JC, CON FUERTE AGITACION, A UNA PRESION PROXIMA A LA ATMOSFERICA.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA LA PREPARACION DE COMPOSICIONES EMPLEADAS EN LA PROTECCION METABOLICA DEL MIOCARDIO.
ES519991A 1982-02-23 1983-02-22 Procedimiento para la obtencion de compuestos derivados del acido 3-hidroxibutanoico. Expired ES8500240A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8203100A FR2521857B1 (fr) 1982-02-23 1982-02-23 Compositions pharmaceutiques contenant de l'acide 3-hydroxybutanoique ou un sel derive de cet acide et sels derives de l'acide 3-hydroxybutanoique et d'une base organique azotee

Publications (2)

Publication Number Publication Date
ES519991A0 ES519991A0 (es) 1984-10-01
ES8500240A1 true ES8500240A1 (es) 1984-10-01

Family

ID=9271331

Family Applications (2)

Application Number Title Priority Date Filing Date
ES519991A Expired ES8500240A1 (es) 1982-02-23 1983-02-22 Procedimiento para la obtencion de compuestos derivados del acido 3-hidroxibutanoico.
ES532880A Granted ES532880A0 (es) 1982-02-23 1984-05-28 Un procedimiento para obtener composiciones farmaceuticas que contienen un derivado del acido 3-hidroxibutanoico y de una base inorganica u organica nitrogenada.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES532880A Granted ES532880A0 (es) 1982-02-23 1984-05-28 Un procedimiento para obtener composiciones farmaceuticas que contienen un derivado del acido 3-hidroxibutanoico y de una base inorganica u organica nitrogenada.

Country Status (21)

Country Link
US (2) US4579955A (es)
EP (1) EP0087192B1 (es)
JP (1) JPS58201746A (es)
KR (1) KR910000143B1 (es)
AT (1) ATE24478T1 (es)
AU (2) AU560757B2 (es)
CA (1) CA1203242A (es)
DE (1) DE3368601D1 (es)
DK (1) DK163235C (es)
ES (2) ES8500240A1 (es)
FI (1) FI79523C (es)
FR (1) FR2521857B1 (es)
GR (1) GR77934B (es)
IE (1) IE54561B1 (es)
IL (1) IL67965A0 (es)
MX (1) MX156855A (es)
NO (1) NO161909C (es)
NZ (1) NZ203279A (es)
PH (1) PH21561A (es)
PT (1) PT76267A (es)
ZA (1) ZA831019B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2051222A1 (es) * 1992-03-12 1994-06-01 Sanmiguel Gabriel Serrano Procedimiento de neutralizacion del acido alfa-hidroxietanoico.

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2521857B1 (fr) * 1982-02-23 1985-10-31 Solvay Compositions pharmaceutiques contenant de l'acide 3-hydroxybutanoique ou un sel derive de cet acide et sels derives de l'acide 3-hydroxybutanoique et d'une base organique azotee
USRE38604E1 (en) 1984-06-22 2004-09-28 Btg International Limited Fluid therapy with L-lactate and/or pyruvate anions
US6020007A (en) * 1984-06-22 2000-02-01 Btg International Limited Fluid therapy with l-lactate and/or pyruvate anions
US4777288A (en) * 1987-06-11 1988-10-11 Pfizer Inc. Process for preparing a 4,4-diphenylbutanoic acid derivative
BE1001209A3 (fr) * 1987-11-19 1989-08-22 Solvay Compositions pharmaceutiques contenant un derive de l'acide 3-hydroxybutanoique choisi parmi les oligomeres de cet acide et les esters de cet acide ou de ces oligomeres avec du 1,3-butanediol.
US5292774A (en) * 1988-07-26 1994-03-08 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Substitution fluid preparation comprising 3-hydroxy-butyric acid (β-hydroxybutric acid) and its salts
DE4113984C2 (de) * 1991-04-29 2002-05-08 Koehler Chemie Dr Franz Salze der 4-Hydroxy-Buttersäure
JP4598203B2 (ja) 1995-12-01 2010-12-15 ビーティージー・インターナショナル・リミテッド 脳機能改善剤
EP1017379B1 (en) * 1997-03-17 2014-12-10 BTG International Limited Therapeutic compositions comprising ketone bodies and precursors thereof
US6316038B1 (en) 1997-03-17 2001-11-13 Btg International Limited Therapeutic compositions
US6323237B1 (en) * 1997-03-17 2001-11-27 Btg International Limited Therapeutic compositions
US20090253781A1 (en) * 2002-05-24 2009-10-08 Btg International Limited Therapeutic compositions
US6613356B1 (en) 2000-10-10 2003-09-02 Victor Vlahakos Weight loss medication and method
GB0420856D0 (en) * 2004-09-20 2004-10-20 Ketocytonyx Inc Cns modulators
EP1778213B1 (en) * 2004-07-16 2017-04-05 BTG International Limited A method for the synthesis of oligomeric compounds
WO2006020179A2 (en) * 2004-07-20 2006-02-23 Ketocytonyx Inc. Oligomeric ketone compounds
WO2006012490A2 (en) * 2004-07-23 2006-02-02 Ketocytonyx Inc. Ketogenic saccharides
WO2006034361A2 (en) * 2004-09-21 2006-03-30 Ketocytonyx Inc. Dopaminergic mimetics
WO2006098767A2 (en) * 2004-09-21 2006-09-21 Ketocytonyx Inc. Treatment of adhd
EP2078522B1 (en) 2006-10-30 2012-09-05 Ophtecs Corporation Composition for treating allergy
DK2914251T3 (da) 2012-11-05 2019-11-04 Us Health Ketonlegemer til beskyttelse af væv mod beskadigelse som følge af ioniseringsstråling
KR20180088809A (ko) 2015-11-19 2018-08-07 가부시키가이샤 오츠카 세이야쿠 코죠 3-히드록시이소발레르산의 1가 양이온염의 결정 및 그 결정의 제조 방법
US11103470B2 (en) 2017-11-22 2021-08-31 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
US11241403B2 (en) 2016-03-11 2022-02-08 Axcess Global Sciences, Llc Beta-hydroxybutyrate mixed salt compositions and methods of use
JP6710098B2 (ja) * 2016-05-10 2020-06-17 大阪瓦斯株式会社 栄養剤組成物及び栄養補助食品
KR20190028441A (ko) * 2016-06-24 2019-03-18 가부시키가이샤 오츠카 세이야쿠 고죠 3-히드록시이소발레르산의 아미노산염의 결정 및 그 제조 방법
US11202769B2 (en) 2017-11-22 2021-12-21 Axcess Global Sciences, Llc Ketone body esters of s-beta-hydroxybutyrate and/or s-1,3-butanediol for modifying metabolic function
US10925843B2 (en) 2018-04-18 2021-02-23 Axcess Global Sciences, Llc Compositions and methods for keto stacking with beta-hydroxybutyrate and acetoacetate
US11944598B2 (en) 2017-12-19 2024-04-02 Axcess Global Sciences, Llc Compositions containing s-beta-hydroxybutyrate or non-racemic mixtures enriched with the s-enatiomer
US11806324B2 (en) 2018-04-18 2023-11-07 Axcess Global Sciences, Llc Beta-hydroxybutyric acid compositions and methods for oral delivery of ketone bodies
US11950616B2 (en) 2019-06-21 2024-04-09 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
CN112341331B (zh) * 2019-08-07 2023-04-07 辽宁科硕营养科技股份有限公司 一种3-羟基丁酸盐及其制备方法与应用
US11969430B1 (en) 2023-03-10 2024-04-30 Axcess Global Sciences, Llc Compositions containing paraxanthine and beta-hydroxybutyrate or precursor for increasing neurological and physiological performance

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2101097A (en) * 1934-07-26 1937-12-07 Wm S Merrell Co Products for rendering the urine bacteriostatic
US2799684A (en) * 1954-06-18 1957-07-16 Food Chemical And Res Lab Inc Crystalline compounds of tryptophane and methods of manufacturing them
NL279760A (es) * 1961-06-17
US3830931A (en) * 1972-11-06 1974-08-20 Felice S De Carnitine and its use in the treatment of arrhythmia and impaired cardiac function
US3879537A (en) * 1973-09-04 1975-04-22 Scott Eugene J Van Treatment of ichthyosiform dermatoses
DE2733202A1 (de) * 1976-08-04 1978-02-09 Agroferm Ag Verfahren zur herstellung der d(-)-3-hydroxybuttersaeure
US4412943A (en) * 1981-02-23 1983-11-01 Kao Soap Co., Ltd. Liquid detergent composition
FR2521857B1 (fr) * 1982-02-23 1985-10-31 Solvay Compositions pharmaceutiques contenant de l'acide 3-hydroxybutanoique ou un sel derive de cet acide et sels derives de l'acide 3-hydroxybutanoique et d'une base organique azotee

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2051222A1 (es) * 1992-03-12 1994-06-01 Sanmiguel Gabriel Serrano Procedimiento de neutralizacion del acido alfa-hidroxietanoico.

Also Published As

Publication number Publication date
DK163235B (da) 1992-02-10
PT76267A (fr) 1983-03-01
FI79523B (fi) 1989-09-29
PH21561A (en) 1987-12-11
KR910000143B1 (ko) 1991-01-21
IL67965A0 (en) 1983-06-15
FR2521857B1 (fr) 1985-10-31
AU560757B2 (en) 1987-04-16
AU1162483A (en) 1983-09-01
FI830603A0 (fi) 1983-02-23
ATE24478T1 (de) 1987-01-15
DK81583A (da) 1983-08-24
US4579955A (en) 1986-04-01
NO830618L (no) 1983-08-24
ES519991A0 (es) 1984-10-01
MX156855A (es) 1988-10-07
EP0087192B1 (fr) 1986-12-30
ZA831019B (en) 1983-11-30
DK81583D0 (da) 1983-02-23
FI830603L (fi) 1983-08-24
KR840003414A (ko) 1984-09-08
FI79523C (fi) 1990-01-10
EP0087192A1 (fr) 1983-08-31
NZ203279A (en) 1985-04-30
ES8506283A1 (es) 1985-07-01
DE3368601D1 (en) 1987-02-05
IE830366L (en) 1983-08-23
DK163235C (da) 1992-06-29
FR2521857A1 (fr) 1983-08-26
NO161909C (no) 1989-10-11
JPS58201746A (ja) 1983-11-24
US4771074A (en) 1988-09-13
ES532880A0 (es) 1985-07-01
CA1203242A (fr) 1986-04-15
NO161909B (no) 1989-07-03
AU6916187A (en) 1987-05-21
IE54561B1 (en) 1989-11-22
GR77934B (es) 1984-09-25
AU602329B2 (en) 1990-10-11

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303