ES8407053A1 - Un procedimiento para la preparacion de nuevos derivados de penem-2-tiosustituidos. - Google Patents
Un procedimiento para la preparacion de nuevos derivados de penem-2-tiosustituidos.Info
- Publication number
- ES8407053A1 ES8407053A1 ES522389A ES522389A ES8407053A1 ES 8407053 A1 ES8407053 A1 ES 8407053A1 ES 522389 A ES522389 A ES 522389A ES 522389 A ES522389 A ES 522389A ES 8407053 A1 ES8407053 A1 ES 8407053A1
- Authority
- ES
- Spain
- Prior art keywords
- composition containing
- hydrogen atom
- penem derivatives
- group
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57081067A JPS58198486A (ja) | 1982-05-14 | 1982-05-14 | ペネムまたはカルバペネム−３−カルボン酸誘導体およびその製法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES522389A0 ES522389A0 (es) | 1984-08-16 |
| ES8407053A1 true ES8407053A1 (es) | 1984-08-16 |
Family
ID=13736043
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES522389A Expired ES8407053A1 (es) | 1982-05-14 | 1983-05-13 | Un procedimiento para la preparacion de nuevos derivados de penem-2-tiosustituidos. |
| ES528491A Expired ES8504815A1 (es) | 1982-05-14 | 1983-12-28 | Un procedimiento para la preparacion de nuevos derivados de penem 2-tiosustituidos |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES528491A Expired ES8504815A1 (es) | 1982-05-14 | 1983-12-28 | Un procedimiento para la preparacion de nuevos derivados de penem 2-tiosustituidos |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4613595A (enExample) |
| JP (1) | JPS58198486A (enExample) |
| CH (1) | CH659072A5 (enExample) |
| DE (1) | DE3317742A1 (enExample) |
| ES (2) | ES8407053A1 (enExample) |
| FR (1) | FR2526798B1 (enExample) |
| GB (1) | GB2121792B (enExample) |
| IT (1) | IT1164226B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5916892A (ja) * | 1982-07-19 | 1984-01-28 | Sankyo Co Ltd | カルバペネム−３−カルボン酸誘導体およびその製法 |
| US4772597A (en) * | 1983-10-14 | 1988-09-20 | Pfizer Inc. | 2-azacycloalkylthiopenem derivatives |
| CA1339860C (en) * | 1985-06-17 | 1998-05-12 | Tsunehiko Soga | Derivatives of penem |
| US4751297A (en) * | 1987-03-20 | 1988-06-14 | Pfizer Inc. | Method for preparation of azetidinone-1-oxoacetate by oxidation of the corresponding 2-hydroxyacetate |
| DE68919508T2 (de) * | 1988-04-01 | 1995-07-20 | Sankyo Co | 2-(Heterocyclylthio)carbapenemderivate, deren Herstellung und deren Verwendung als Antibiotika. |
| US5242914A (en) * | 1988-04-01 | 1993-09-07 | Sankyo Company, Limited | 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics |
| JP2783683B2 (ja) * | 1992-12-21 | 1998-08-06 | ジョン グン ダン コーポレーション | ２−（２−置換されたピロリジン−４−イル）チオ−カバペネム誘導体 |
| US20250282796A1 (en) * | 2022-06-01 | 2025-09-11 | The Johns Hopkins University | Penem antibacterials against mycobacterial pathogens and d,d- and l,d transpeptidases |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4168314A (en) * | 1977-11-17 | 1979-09-18 | Merck & Co., Inc. | 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid |
| EP0003960B1 (de) * | 1978-02-02 | 1983-06-29 | Ciba-Geigy Ag | 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate |
| DE2961882D1 (en) * | 1978-08-25 | 1982-03-04 | Beecham Group Plc | Beta-lactam anti-bacterials, compositions containing them and a process for their preparation |
| JPS55153789A (en) * | 1979-04-11 | 1980-11-29 | Sankyo Co Ltd | Penem-3-carboxylic acid derivative and its preparation |
| EP0082133A3 (en) * | 1979-04-19 | 1983-07-20 | Merck & Co. Inc. | A process for preparing intermediates useful for preparing 2-substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids |
| US4386030A (en) * | 1979-12-31 | 1983-05-31 | Merck & Co., Inc. | Process for preparing 6-(1'-hydroxyethyl)-2-substituted-pen-2-em-3-carboxylic acid |
| DE3176517D1 (en) * | 1980-04-24 | 1987-12-17 | Beecham Group Plc | Beta-lactam compounds, their preparation and use |
| GB2083462B (en) * | 1980-08-16 | 1984-05-02 | Beecham Group Ltd | 2-thiopenem derivatives |
| JPS57176988A (en) * | 1981-04-09 | 1982-10-30 | Sankyo Co Ltd | Penam-3-carboxylic acid derivative and its preparation |
| DE3277696D1 (en) * | 1981-07-15 | 1987-12-23 | Sumitomo Pharma | Carboxylic beta-lactam compounds and the preparation thereof |
| US4435412A (en) * | 1982-11-29 | 1984-03-06 | Schering Corporation | 5R,6S,8R-2-(1-Methyl-2-imidazolylmethylthio)-6-(1-hydroxyethyl)penem-3-carboxylic acid |
-
1982
- 1982-05-14 JP JP57081067A patent/JPS58198486A/ja active Granted
-
1983
- 1983-05-13 IT IT21084/83A patent/IT1164226B/it active
- 1983-05-13 CH CH2629/83A patent/CH659072A5/de not_active IP Right Cessation
- 1983-05-13 ES ES522389A patent/ES8407053A1/es not_active Expired
- 1983-05-13 US US06/494,570 patent/US4613595A/en not_active Expired - Fee Related
- 1983-05-16 GB GB08313399A patent/GB2121792B/en not_active Expired
- 1983-05-16 FR FR8308085A patent/FR2526798B1/fr not_active Expired
- 1983-05-16 DE DE19833317742 patent/DE3317742A1/de active Granted
- 1983-12-28 ES ES528491A patent/ES8504815A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US4613595A (en) | 1986-09-23 |
| GB2121792A (en) | 1984-01-04 |
| FR2526798B1 (fr) | 1985-10-04 |
| ES528491A0 (es) | 1985-05-01 |
| IT8321084A1 (it) | 1984-11-13 |
| FR2526798A1 (fr) | 1983-11-18 |
| ES522389A0 (es) | 1984-08-16 |
| DE3317742C2 (enExample) | 1991-08-29 |
| JPS58198486A (ja) | 1983-11-18 |
| IT8321084A0 (it) | 1983-05-13 |
| GB8313399D0 (en) | 1983-06-22 |
| DE3317742A1 (de) | 1983-11-17 |
| ES8504815A1 (es) | 1985-05-01 |
| CH659072A5 (de) | 1986-12-31 |
| JPH0318638B2 (enExample) | 1991-03-13 |
| IT1164226B (it) | 1987-04-08 |
| GB2121792B (en) | 1986-01-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19971001 |