ES8405640A1 - Un metodo para preparar microcpsulas de flujo libre - Google Patents
Un metodo para preparar microcpsulas de flujo libreInfo
- Publication number
- ES8405640A1 ES8405640A1 ES524175A ES524175A ES8405640A1 ES 8405640 A1 ES8405640 A1 ES 8405640A1 ES 524175 A ES524175 A ES 524175A ES 524175 A ES524175 A ES 524175A ES 8405640 A1 ES8405640 A1 ES 8405640A1
- Authority
- ES
- Spain
- Prior art keywords
- flowing
- preparing free
- ethylcellulose
- ethylcellulose microcapsules
- microcapsules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
- B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
- B01J13/12—Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
- Y10T428/2985—Solid-walled microcapsule from synthetic polymer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2989—Microcapsule with solid core [includes liposome]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
METODO PARA PREPARAR MICROCAPSULAS DE ETILCELULOSA DE FLUJO LIBRE.COMPRENDE VARIAS ETAPAS: A) DISPERSAR PARTICULAS DE UN MATERIAL NUCLEAR EN UNA SOLUCION DE CICLOEXANO QUE CONTIENE ETILCELULOSA Y UN COMPUESTO HIDROCARBONADO, SIENDO SOLUBLE DICHO COMPUESTO EN CICLOEXANO Y TENIENDO UN PESO MOLECULAR DE 150 A 3.000 Y UN PARAMETRO DE SOLUBILIDAD (8 A 25JC0 DE 7 A 10 (CAL/M)1/2; 2) ENFRIAR LA DISPERSION HASTA QUE SE SEPARE LA ETILCELULOSA DE LA DISPERSION PARA FORMAR LAS PAREDES DE REVESTIMIENTO SOBRE Y ALREDEDOR DE LAS PARTICULAS DEL MATERIALNUCLEAR; Y 3) RECUPERAR DEL MEDIO LAS PARTICULAS QUE SE HAN FORMADO. EL COMPUESTO HIDROCARBONADO ES UN MIEMBRO SELECCIONADO DEL GRUPO FORMADO POR PARAFINA LIQUIDA, VASELINA, CERESINA, PARAFINA, CERA MICROCRISTALINA, ESCUALANO, ESCUALENO, PRISTANO, POLIBUTADIENO (PESO MOLECULAR: 500 A 3.000), POLIBUTENO (PESO MOLECULAR: 200 A 3.000, POLIISOPRENO (PESO MOLECULAR: 1.000 A 3.000) Y COPOLIMERO DE BUTADIENO-ESTIRENO (PESO MOLECULAR: 1.500 A 3.000).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP57124829A JPS5916821A (ja) | 1982-07-16 | 1982-07-16 | 非凝集性マイクロカプセルの製法 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES524175A0 ES524175A0 (es) | 1984-06-16 |
ES8405640A1 true ES8405640A1 (es) | 1984-06-16 |
Family
ID=14895124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES524175A Expired ES8405640A1 (es) | 1982-07-16 | 1983-07-15 | Un metodo para preparar microcpsulas de flujo libre |
Country Status (11)
Country | Link |
---|---|
US (1) | US4542042A (es) |
EP (1) | EP0099109B1 (es) |
JP (1) | JPS5916821A (es) |
KR (1) | KR890000828B1 (es) |
AT (1) | ATE18863T1 (es) |
CA (1) | CA1212868A (es) |
DE (1) | DE3362784D1 (es) |
DK (1) | DK161744C (es) |
ES (1) | ES8405640A1 (es) |
HK (1) | HK16988A (es) |
SG (1) | SG81287G (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU591248B2 (en) * | 1986-03-27 | 1989-11-30 | Kinaform Technology, Inc. | Sustained-release pharaceutical preparation |
JPH0721444B2 (ja) * | 1986-08-19 | 1995-03-08 | 株式会社島津製作所 | 材料試験機の変位補正装置 |
US4784879A (en) * | 1987-07-20 | 1988-11-15 | Dow Corning Corporation | Method for preparing a microencapsulated compound of a platinum group metal |
USRE33749E (en) * | 1987-07-20 | 1991-11-19 | Dow Corning Corporation | Storage stable heat curable organosiloxane compositions containing microencapsulated platinum-containing catalysts |
FR2630647B1 (fr) * | 1988-04-27 | 1991-08-16 | Sanofi Sa | Microbilles de diltiazem, leur procede de fabrication et compositions pharmaceutiques a liberation prolongee les contenant |
US5344657A (en) * | 1988-04-27 | 1994-09-06 | Elf Sanofi | Microbeads of diltiazem, a process for their manufacture and a substained-release pharmaceutical composition containing them |
FR2640876B1 (es) * | 1988-12-28 | 1993-09-24 | Jouveinal Sa | |
HU201869B (en) * | 1988-12-30 | 1991-01-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing microcapsules of quick dissolving active component |
CH677188A5 (es) * | 1989-03-16 | 1991-04-30 | Mono Cosmetic S A | |
US4992277A (en) * | 1989-08-25 | 1991-02-12 | Schering Corporation | Immediate release diltiazem formulation |
US5000962A (en) * | 1989-08-25 | 1991-03-19 | Schering Corporation | Long acting diltiazem formulation |
US5252337A (en) * | 1991-06-25 | 1993-10-12 | Eurand America, Inc. | Controlled release calcium channel blocker microcapsules |
US6143211A (en) * | 1995-07-21 | 2000-11-07 | Brown University Foundation | Process for preparing microparticles through phase inversion phenomena |
US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
FR2752162B1 (fr) * | 1996-08-07 | 1998-11-06 | Jouveinal Lab | Comprime de maleate de trimebutine pellicule |
IL129242A0 (en) * | 1996-10-01 | 2000-02-17 | Cima Labs Inc | Taste-masked microcapsule compositions and methods of manufacture |
EP1423175B1 (en) * | 2001-08-08 | 2013-10-02 | Brown University Research Foundation | Methods for micronization of hydrophobic drugs |
US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
AU2002360549A1 (en) * | 2001-12-10 | 2003-06-23 | Spherics, Inc. | Methods and products useful in the formation and isolation of microparticles |
US8367111B2 (en) | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
US7632521B2 (en) * | 2003-07-15 | 2009-12-15 | Eurand, Inc. | Controlled release potassium chloride tablets |
US8545881B2 (en) * | 2004-04-19 | 2013-10-01 | Eurand Pharmaceuticals, Ltd. | Orally disintegrating tablets and methods of manufacture |
US8747895B2 (en) | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
NZ728442A (en) * | 2004-10-21 | 2018-05-25 | Adare Pharmaceuticals Inc | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
US20060105038A1 (en) * | 2004-11-12 | 2006-05-18 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions prepared by coacervation |
US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
MX2012006240A (es) | 2009-12-02 | 2012-10-03 | Aptalis Pharma Ltd | Microcapsulas de fexofenadina y composiciones que contienen las mismas. |
UY33173A (es) * | 2010-01-08 | 2011-07-29 | Eurand Inc | |
WO2018180966A1 (ja) * | 2017-03-28 | 2018-10-04 | 富士フイルム株式会社 | マイクロカプセル及びその製造方法 |
CN114480210A (zh) * | 2022-02-25 | 2022-05-13 | 万之源生物科技有限公司 | 一种治理盐碱化促棉花生长的复合菌微胶囊的制备方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT631615A (es) * | 1960-02-26 | |||
NL129081C (es) * | 1960-10-28 | |||
US3341416A (en) * | 1963-12-11 | 1967-09-12 | Ncr Co | Encapsulation of aspirin in ethylcellulose and its product |
US3626056A (en) * | 1967-11-02 | 1971-12-07 | Bristol Myers Co | Oral antibiotic product |
JPS528795B2 (es) * | 1971-12-30 | 1977-03-11 | ||
DE2418130A1 (de) * | 1973-04-18 | 1974-11-14 | Gen Electric | Verfahren zum kontinuierlichen herstellen von elektrischen heizeinheiten und vorrichtung zur durchfuehrung des verfahrens |
US4123382A (en) * | 1973-05-25 | 1978-10-31 | Merck & Co., Inc. | Method of microencapsulation |
JPS5432614A (en) * | 1977-08-11 | 1979-03-10 | Tanabe Seiyaku Co Ltd | Preparation of microcapsules containing pharmaceuticals |
JPS6045845B2 (ja) * | 1979-10-31 | 1985-10-12 | 田辺製薬株式会社 | 医薬物質含有マイクロカプセルの製法 |
JPS56152739A (en) * | 1980-04-25 | 1981-11-26 | Tanabe Seiyaku Co Ltd | Production of microcapsule |
-
1982
- 1982-07-16 JP JP57124829A patent/JPS5916821A/ja active Granted
-
1983
- 1983-07-01 US US06/510,202 patent/US4542042A/en not_active Expired - Fee Related
- 1983-07-07 CA CA000431964A patent/CA1212868A/en not_active Expired
- 1983-07-12 KR KR1019830003176A patent/KR890000828B1/ko not_active IP Right Cessation
- 1983-07-12 DE DE8383106827T patent/DE3362784D1/de not_active Expired
- 1983-07-12 EP EP83106827A patent/EP0099109B1/en not_active Expired
- 1983-07-12 AT AT83106827T patent/ATE18863T1/de not_active IP Right Cessation
- 1983-07-15 ES ES524175A patent/ES8405640A1/es not_active Expired
- 1983-07-15 DK DK327583A patent/DK161744C/da not_active IP Right Cessation
-
1987
- 1987-10-09 SG SG812/87A patent/SG81287G/en unknown
-
1988
- 1988-03-03 HK HK169/88A patent/HK16988A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
KR840005335A (ko) | 1984-11-12 |
JPS5916821A (ja) | 1984-01-28 |
DK327583D0 (da) | 1983-07-15 |
CA1212868A (en) | 1986-10-21 |
DK327583A (da) | 1984-01-17 |
EP0099109B1 (en) | 1986-04-02 |
US4542042A (en) | 1985-09-17 |
KR890000828B1 (ko) | 1989-04-10 |
DK161744B (da) | 1991-08-12 |
DE3362784D1 (en) | 1986-05-07 |
HK16988A (en) | 1988-03-11 |
ATE18863T1 (de) | 1986-04-15 |
DK161744C (da) | 1992-02-17 |
ES524175A0 (es) | 1984-06-16 |
EP0099109A1 (en) | 1984-01-25 |
JPS6259971B2 (es) | 1987-12-14 |
SG81287G (en) | 1988-04-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970519 |