ES8403140A1 - Un procedimiento para la preparacion de glicosidos de antraciclina. - Google Patents
Un procedimiento para la preparacion de glicosidos de antraciclina.Info
- Publication number
- ES8403140A1 ES8403140A1 ES519255A ES519255A ES8403140A1 ES 8403140 A1 ES8403140 A1 ES 8403140A1 ES 519255 A ES519255 A ES 519255A ES 519255 A ES519255 A ES 519255A ES 8403140 A1 ES8403140 A1 ES 8403140A1
- Authority
- ES
- Spain
- Prior art keywords
- glycosides
- desmetoxy
- tridesoxy
- dimethyl
- chloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930182470 glycoside Natural products 0.000 title abstract 2
- 150000002338 glycosides Chemical class 0.000 title abstract 2
- 229940045799 anthracyclines and related substance Drugs 0.000 title 1
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 2
- 201000009030 Carcinoma Diseases 0.000 abstract 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 abstract 1
- 238000005904 alkaline hydrolysis reaction Methods 0.000 abstract 1
- STQGQHZAVUOBTE-VGBVRHCVSA-N daunorubicin Chemical class O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(C)=O)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 STQGQHZAVUOBTE-VGBVRHCVSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002808 molecular sieve Substances 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 229910052709 silver Inorganic materials 0.000 abstract 1
- 239000004332 silver Substances 0.000 abstract 1
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8202080 | 1982-01-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES519255A0 ES519255A0 (es) | 1984-03-01 |
| ES8403140A1 true ES8403140A1 (es) | 1984-03-01 |
Family
ID=10527864
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES519255A Expired ES8403140A1 (es) | 1982-01-26 | 1983-01-25 | Un procedimiento para la preparacion de glicosidos de antraciclina. |
Country Status (28)
| Country | Link |
|---|---|
| JP (1) | JPS58128396A (OSRAM) |
| KR (1) | KR900006214B1 (OSRAM) |
| AT (1) | AT378776B (OSRAM) |
| AU (1) | AU551700B2 (OSRAM) |
| BE (1) | BE895687A (OSRAM) |
| CA (1) | CA1197237A (OSRAM) |
| CH (1) | CH657622A5 (OSRAM) |
| CS (1) | CS235979B2 (OSRAM) |
| DE (1) | DE3301489A1 (OSRAM) |
| DK (1) | DK157322C (OSRAM) |
| ES (1) | ES8403140A1 (OSRAM) |
| FI (1) | FI74977C (OSRAM) |
| FR (1) | FR2520365B1 (OSRAM) |
| GB (1) | GB2116169B (OSRAM) |
| GR (1) | GR77890B (OSRAM) |
| HU (1) | HU192784B (OSRAM) |
| IE (1) | IE53750B1 (OSRAM) |
| IL (1) | IL67709A (OSRAM) |
| IT (1) | IT1210482B (OSRAM) |
| NL (1) | NL8300150A (OSRAM) |
| NO (1) | NO153456C (OSRAM) |
| NZ (1) | NZ203047A (OSRAM) |
| PH (1) | PH19130A (OSRAM) |
| PT (1) | PT76113A (OSRAM) |
| SE (1) | SE461591B (OSRAM) |
| SU (1) | SU1187724A3 (OSRAM) |
| YU (1) | YU43536B (OSRAM) |
| ZA (1) | ZA83450B (OSRAM) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2182926B (en) * | 1985-11-19 | 1989-10-04 | Erba Farmitalia | Nitro anthracyclines, process for their preparation and use thereof |
| GB8708927D0 (en) * | 1987-04-14 | 1987-05-20 | Erba Farmitalia | Chiral synthesis of anthracyclines |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1509875A (en) * | 1976-06-14 | 1978-05-04 | Farmaceutici Italia | Optically active anthracyclinones and anthracycline glycosides |
| GB1573037A (en) * | 1977-05-05 | 1980-08-13 | Farmaceutici Italia | Anthracyclines |
| EP0022515B1 (en) * | 1979-07-04 | 1983-08-03 | FARMITALIA CARLO ERBA S.p.A. | Anthracycline glycosides, process for their preparation and therapeutical composition containing them |
| DE3100968A1 (de) * | 1980-01-16 | 1982-01-14 | Farmitalia Carlo Erba S.p.A., 20159 Milano | Anthracyclinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
-
1983
- 1983-01-14 NL NL8300150A patent/NL8300150A/nl not_active Application Discontinuation
- 1983-01-17 AU AU10525/83A patent/AU551700B2/en not_active Ceased
- 1983-01-17 YU YU89/83A patent/YU43536B/xx unknown
- 1983-01-17 FI FI830155A patent/FI74977C/fi not_active IP Right Cessation
- 1983-01-17 GB GB08301178A patent/GB2116169B/en not_active Expired
- 1983-01-18 NZ NZ203047A patent/NZ203047A/en unknown
- 1983-01-18 DE DE19833301489 patent/DE3301489A1/de active Granted
- 1983-01-18 IL IL67709A patent/IL67709A/xx unknown
- 1983-01-18 CA CA000419718A patent/CA1197237A/en not_active Expired
- 1983-01-18 AT AT0015683A patent/AT378776B/de not_active IP Right Cessation
- 1983-01-18 IT IT8319147A patent/IT1210482B/it active
- 1983-01-19 JP JP58005974A patent/JPS58128396A/ja active Granted
- 1983-01-19 PH PH28401A patent/PH19130A/en unknown
- 1983-01-19 PT PT76113A patent/PT76113A/pt unknown
- 1983-01-19 CS CS83374A patent/CS235979B2/cs unknown
- 1983-01-20 CH CH317/83A patent/CH657622A5/it not_active IP Right Cessation
- 1983-01-21 SE SE8300324A patent/SE461591B/sv not_active IP Right Cessation
- 1983-01-24 BE BE0/209955A patent/BE895687A/fr unknown
- 1983-01-24 ZA ZA83450A patent/ZA83450B/xx unknown
- 1983-01-24 GR GR70317A patent/GR77890B/el unknown
- 1983-01-24 SU SU833542550A patent/SU1187724A3/ru active
- 1983-01-25 DK DK027683A patent/DK157322C/da not_active IP Right Cessation
- 1983-01-25 KR KR1019830000279A patent/KR900006214B1/ko not_active Expired
- 1983-01-25 ES ES519255A patent/ES8403140A1/es not_active Expired
- 1983-01-25 FR FR8301078A patent/FR2520365B1/fr not_active Expired
- 1983-01-25 IE IE144/83A patent/IE53750B1/en unknown
- 1983-01-25 NO NO830234A patent/NO153456C/no unknown
- 1983-01-25 HU HU83240A patent/HU192784B/hu not_active IP Right Cessation
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